Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia

Detalhes bibliográficos
Autor(a) principal: do Sambo, Maria Rosário
Data de Publicação: 2015
Outros Autores: Penha-Gonçalves, Carlos, Trovoada, Maria Jesus, Costa, João, Lardoeyt, Roberto, Coutinho, António
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.7/498
Resumo: This deposit is composed by the main article, and it hasn't any supplementary materials associated.
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spelling Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemiaMalariaSickle cellHyperparasitaemiaSevere malariaHbSAngolaThis deposit is composed by the main article, and it hasn't any supplementary materials associated.Haemoglobin S (HbS) is the gene known to confer the strongest advantage against malaria morbidity and mortality. Multiple HbS effects have been described resulting in protection against parasitaemia and reduction of severe malaria risk. This study aimed to explore HbS protection against severe malaria and Plasmodium falciparum parasitaemia in Angolan children exhibiting different severe malaria syndromes.Instituto Gulbenkian de Ciência.BioMed CentralARCAdo Sambo, Maria RosárioPenha-Gonçalves, CarlosTrovoada, Maria JesusCosta, JoãoLardoeyt, RobertoCoutinho, António2015-11-17T15:54:52Z2015-10-072015-10-07T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.7/498eng10.1186/s12936-015-0920-zinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-11-29T14:34:52Zoai:arca.igc.gulbenkian.pt:10400.7/498Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:46.213369Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
title Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
spellingShingle Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
do Sambo, Maria Rosário
Malaria
Sickle cell
Hyperparasitaemia
Severe malaria
HbS
Angola
title_short Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
title_full Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
title_fullStr Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
title_full_unstemmed Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
title_sort Quantitative trait locus analysis of parasite density reveals that HbS gene carriage protects severe malaria patients against Plasmodium falciparum hyperparasitaemia
author do Sambo, Maria Rosário
author_facet do Sambo, Maria Rosário
Penha-Gonçalves, Carlos
Trovoada, Maria Jesus
Costa, João
Lardoeyt, Roberto
Coutinho, António
author_role author
author2 Penha-Gonçalves, Carlos
Trovoada, Maria Jesus
Costa, João
Lardoeyt, Roberto
Coutinho, António
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv ARCA
dc.contributor.author.fl_str_mv do Sambo, Maria Rosário
Penha-Gonçalves, Carlos
Trovoada, Maria Jesus
Costa, João
Lardoeyt, Roberto
Coutinho, António
dc.subject.por.fl_str_mv Malaria
Sickle cell
Hyperparasitaemia
Severe malaria
HbS
Angola
topic Malaria
Sickle cell
Hyperparasitaemia
Severe malaria
HbS
Angola
description This deposit is composed by the main article, and it hasn't any supplementary materials associated.
publishDate 2015
dc.date.none.fl_str_mv 2015-11-17T15:54:52Z
2015-10-07
2015-10-07T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.7/498
url http://hdl.handle.net/10400.7/498
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1186/s12936-015-0920-z
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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