Scaffold fabrication technologies and structure/function properties in bone tissue engineering

Detalhes bibliográficos
Autor(a) principal: Collins, Maurice N.
Data de Publicação: 2021
Outros Autores: Ren, Guang, Young, Kieran, Pina, Sandra Cristina Almeida, Reis, R. L., Oliveira, J. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/70679
Resumo: Bone tissue engineering (BTE) is a rapidly growing field aiming to create a biofunctional tissue that can integrate and degrade in vivo to treat diseased or damaged tissue. It has become evident that scaffold fabrication techniques are very important in dictating the final structural, mechanical properties, and biological response of the implanted biomaterials. A comprehensive review of the current accomplishments on scaffold fabrication techniques, their structure, and function properties for BTE is provided herein. Different types of biomaterials ranging from inorganic biomaterials to natural and synthetic polymers and related composites for scaffold processing are presented. Emergent scaffolding techniques such as electrospinning, freezeâ drying, bioprinting, and decellularization are also discussed. Strategies to improve vascularization potential and immunomodulation, which is considered a grand challenge in BTE scaffolding, are also presented.
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spelling Scaffold fabrication technologies and structure/function properties in bone tissue engineeringBioprintingBoneElectrospinningImmunomodulationScaffoldsTissue engineeringVascularizationbonesScience & TechnologyBone tissue engineering (BTE) is a rapidly growing field aiming to create a biofunctional tissue that can integrate and degrade in vivo to treat diseased or damaged tissue. It has become evident that scaffold fabrication techniques are very important in dictating the final structural, mechanical properties, and biological response of the implanted biomaterials. A comprehensive review of the current accomplishments on scaffold fabrication techniques, their structure, and function properties for BTE is provided herein. Different types of biomaterials ranging from inorganic biomaterials to natural and synthetic polymers and related composites for scaffold processing are presented. Emergent scaffolding techniques such as electrospinning, freezeâ drying, bioprinting, and decellularization are also discussed. Strategies to improve vascularization potential and immunomodulation, which is considered a grand challenge in BTE scaffolding, are also presented.M.N.C. and G.R. contributed equally to this work. The authors thank the financial support from the Portuguese Foundation for Science and Technology for the funds provided under the distinctions attributed to J.M.O. (IF/01285/2015) and S.P. (CEECIND/03673/2017), and for the project 3BIOMED (ref. JICAM/0001/2017).WileyUniversidade do MinhoCollins, Maurice N.Ren, GuangYoung, KieranPina, Sandra Cristina AlmeidaReis, R. L.Oliveira, J. M.2021-032021-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/70679engCollins M. N., Ren G., Young K., Pina S., Reis R. L., Oliveira J. M. Scaffold Fabrication Technologies and Structure/Function Properties in Bone Tissue Engineering, Advanced Functional Materials, doi:10.1002/adfm.202010609, 20211616-302810.1002/adfm.202010609https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202010609info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:05:35Zoai:repositorium.sdum.uminho.pt:1822/70679Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:56:03.465617Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Scaffold fabrication technologies and structure/function properties in bone tissue engineering
title Scaffold fabrication technologies and structure/function properties in bone tissue engineering
spellingShingle Scaffold fabrication technologies and structure/function properties in bone tissue engineering
Collins, Maurice N.
Bioprinting
Bone
Electrospinning
Immunomodulation
Scaffolds
Tissue engineering
Vascularization
bones
Science & Technology
title_short Scaffold fabrication technologies and structure/function properties in bone tissue engineering
title_full Scaffold fabrication technologies and structure/function properties in bone tissue engineering
title_fullStr Scaffold fabrication technologies and structure/function properties in bone tissue engineering
title_full_unstemmed Scaffold fabrication technologies and structure/function properties in bone tissue engineering
title_sort Scaffold fabrication technologies and structure/function properties in bone tissue engineering
author Collins, Maurice N.
author_facet Collins, Maurice N.
Ren, Guang
Young, Kieran
Pina, Sandra Cristina Almeida
Reis, R. L.
Oliveira, J. M.
author_role author
author2 Ren, Guang
Young, Kieran
Pina, Sandra Cristina Almeida
Reis, R. L.
Oliveira, J. M.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Collins, Maurice N.
Ren, Guang
Young, Kieran
Pina, Sandra Cristina Almeida
Reis, R. L.
Oliveira, J. M.
dc.subject.por.fl_str_mv Bioprinting
Bone
Electrospinning
Immunomodulation
Scaffolds
Tissue engineering
Vascularization
bones
Science & Technology
topic Bioprinting
Bone
Electrospinning
Immunomodulation
Scaffolds
Tissue engineering
Vascularization
bones
Science & Technology
description Bone tissue engineering (BTE) is a rapidly growing field aiming to create a biofunctional tissue that can integrate and degrade in vivo to treat diseased or damaged tissue. It has become evident that scaffold fabrication techniques are very important in dictating the final structural, mechanical properties, and biological response of the implanted biomaterials. A comprehensive review of the current accomplishments on scaffold fabrication techniques, their structure, and function properties for BTE is provided herein. Different types of biomaterials ranging from inorganic biomaterials to natural and synthetic polymers and related composites for scaffold processing are presented. Emergent scaffolding techniques such as electrospinning, freezeâ drying, bioprinting, and decellularization are also discussed. Strategies to improve vascularization potential and immunomodulation, which is considered a grand challenge in BTE scaffolding, are also presented.
publishDate 2021
dc.date.none.fl_str_mv 2021-03
2021-03-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/70679
url http://hdl.handle.net/1822/70679
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Collins M. N., Ren G., Young K., Pina S., Reis R. L., Oliveira J. M. Scaffold Fabrication Technologies and Structure/Function Properties in Bone Tissue Engineering, Advanced Functional Materials, doi:10.1002/adfm.202010609, 2021
1616-3028
10.1002/adfm.202010609
https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.202010609
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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