Anemia in Chronic Kidney Disease: The State of the Art

Detalhes bibliográficos
Autor(a) principal: Farinha, Ana
Data de Publicação: 2022
Outros Autores: Robalo Nunes, António, Mairos, João, Fonseca, Cândida
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17284
Resumo: The aging of the population has led to an increased prevalence of chronic diseases such as chronic kidney disease. Anemia is one of the most frequent complications of chronic kidney disease, with an impact not only on the quality of life but also on the patient’s prognosis and associated costs. Knowledge in this therapeutic area has increased significantly: from the appearance of recombinant erythropoietin in 1989, through the use of increasing doses of parenteral iron and, more recently, to new molecules such as hypoxia-inducible factor inhibitors. The aim of this article is to present a pragmatic review of the state of the art in the epidemiology, pathophysiology, diagnosis and treatment of anemia associated with chronic kidney disease.
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spelling Anemia in Chronic Kidney Disease: The State of the ArtAnemia da Doença Renal Crónica: O Estado da ArteAnemia/diagnosisAnemia/drug therapyAnemiaIron-DeficiencyProlyl-Hydroxylase Inhibitors/therapeutic useRenal InsufficiencyChronic/complicationsAnemia/diagnósticoAnemia/tratamento farmacológicoAnemia FerropénicaDoença Renal Crónica/complicaçõesInibidores de Prolil-Hidrolase/uso terapêuticoThe aging of the population has led to an increased prevalence of chronic diseases such as chronic kidney disease. Anemia is one of the most frequent complications of chronic kidney disease, with an impact not only on the quality of life but also on the patient’s prognosis and associated costs. Knowledge in this therapeutic area has increased significantly: from the appearance of recombinant erythropoietin in 1989, through the use of increasing doses of parenteral iron and, more recently, to new molecules such as hypoxia-inducible factor inhibitors. The aim of this article is to present a pragmatic review of the state of the art in the epidemiology, pathophysiology, diagnosis and treatment of anemia associated with chronic kidney disease.O envelhecimento populacional tem-se traduzido no aumento de prevalência de doenças crónicas como a doença renal crónica. A anemia é uma das complicações mais frequentes da doença renal crónica, com impacto não só na qualidade de vida como no prognóstico do doente e nos custos associados. O conhecimento nesta área terapêutica tem aumentado de forma significativa: desde o aparecimento da eritropoietina recombinante em 1989, passando pelo uso de doses crescentes de ferro parentérico e, mais recentemente, a novas moléculas como os inibidores do hypoxia-inducible factor. Os autores pretendem rever, de uma forma pragmática, o estado da arte da anemia associada à doença renal crónica, desde a epidemiologia, à fisiopatologia, ao diagnóstico e ao tratamento.Ordem dos Médicos2022-07-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17284oai:ojs.www.actamedicaportuguesa.com:article/17284Acta Médica Portuguesa; Vol. 35 No. 10 (2022): October; 758-764Acta Médica Portuguesa; Vol. 35 N.º 10 (2022): Outubro; 758-7641646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17284https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17284/6697Direitos de Autor (c) 2022 Acta Médica Portuguesahttp://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessFarinha, AnaRobalo Nunes, AntónioMairos, JoãoFonseca, Cândida2022-12-20T11:08:00Zoai:ojs.www.actamedicaportuguesa.com:article/17284Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:55.182791Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Anemia in Chronic Kidney Disease: The State of the Art
Anemia da Doença Renal Crónica: O Estado da Arte
title Anemia in Chronic Kidney Disease: The State of the Art
spellingShingle Anemia in Chronic Kidney Disease: The State of the Art
Farinha, Ana
Anemia/diagnosis
Anemia/drug therapy
Anemia
Iron-Deficiency
Prolyl-Hydroxylase Inhibitors/therapeutic use
Renal Insufficiency
Chronic/complications
Anemia/diagnóstico
Anemia/tratamento farmacológico
Anemia Ferropénica
Doença Renal Crónica/complicações
Inibidores de Prolil-Hidrolase/uso terapêutico
title_short Anemia in Chronic Kidney Disease: The State of the Art
title_full Anemia in Chronic Kidney Disease: The State of the Art
title_fullStr Anemia in Chronic Kidney Disease: The State of the Art
title_full_unstemmed Anemia in Chronic Kidney Disease: The State of the Art
title_sort Anemia in Chronic Kidney Disease: The State of the Art
author Farinha, Ana
author_facet Farinha, Ana
Robalo Nunes, António
Mairos, João
Fonseca, Cândida
author_role author
author2 Robalo Nunes, António
Mairos, João
Fonseca, Cândida
author2_role author
author
author
dc.contributor.author.fl_str_mv Farinha, Ana
Robalo Nunes, António
Mairos, João
Fonseca, Cândida
dc.subject.por.fl_str_mv Anemia/diagnosis
Anemia/drug therapy
Anemia
Iron-Deficiency
Prolyl-Hydroxylase Inhibitors/therapeutic use
Renal Insufficiency
Chronic/complications
Anemia/diagnóstico
Anemia/tratamento farmacológico
Anemia Ferropénica
Doença Renal Crónica/complicações
Inibidores de Prolil-Hidrolase/uso terapêutico
topic Anemia/diagnosis
Anemia/drug therapy
Anemia
Iron-Deficiency
Prolyl-Hydroxylase Inhibitors/therapeutic use
Renal Insufficiency
Chronic/complications
Anemia/diagnóstico
Anemia/tratamento farmacológico
Anemia Ferropénica
Doença Renal Crónica/complicações
Inibidores de Prolil-Hidrolase/uso terapêutico
description The aging of the population has led to an increased prevalence of chronic diseases such as chronic kidney disease. Anemia is one of the most frequent complications of chronic kidney disease, with an impact not only on the quality of life but also on the patient’s prognosis and associated costs. Knowledge in this therapeutic area has increased significantly: from the appearance of recombinant erythropoietin in 1989, through the use of increasing doses of parenteral iron and, more recently, to new molecules such as hypoxia-inducible factor inhibitors. The aim of this article is to present a pragmatic review of the state of the art in the epidemiology, pathophysiology, diagnosis and treatment of anemia associated with chronic kidney disease.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-15
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17284
oai:ojs.www.actamedicaportuguesa.com:article/17284
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17284
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/17284
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17284
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17284/6697
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2022 Acta Médica Portuguesa
http://creativecommons.org/licenses/by-nc/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2022 Acta Médica Portuguesa
http://creativecommons.org/licenses/by-nc/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 35 No. 10 (2022): October; 758-764
Acta Médica Portuguesa; Vol. 35 N.º 10 (2022): Outubro; 758-764
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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