Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives
Autor(a) principal: | |
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Data de Publicação: | 2000 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/1822/2187 |
Resumo: | Several b-substituted alanines are synthesised in high yields by a Michael addition of nucleophiles to N-acyl,N-tert-butyloxycarbonyl-dehydroalanine methyl ester, using mild reaction conditions and simple work-up procedures. The same method can be applied to dipeptides containing dehydroalanine. |
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Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivativesScience & TechnologySeveral b-substituted alanines are synthesised in high yields by a Michael addition of nucleophiles to N-acyl,N-tert-butyloxycarbonyl-dehydroalanine methyl ester, using mild reaction conditions and simple work-up procedures. The same method can be applied to dipeptides containing dehydroalanine.Royal Society of ChemistryUniversidade do MinhoFerreira, Paula M. T.Maia, Hernâni L. S.Monteiro, Luís S.Sacramento, JoanaSebastião, Joana20002000-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/2187eng“Journal of the chemical society. Perkin transactions”. 1 (2000) 3317-3324.1470-435810.1039/b003353ginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:55:08Zoai:repositorium.sdum.uminho.pt:1822/2187Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:44:39.903585Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives |
title |
Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives |
spellingShingle |
Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives Ferreira, Paula M. T. Science & Technology |
title_short |
Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives |
title_full |
Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives |
title_fullStr |
Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives |
title_full_unstemmed |
Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives |
title_sort |
Synthesis of b-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives |
author |
Ferreira, Paula M. T. |
author_facet |
Ferreira, Paula M. T. Maia, Hernâni L. S. Monteiro, Luís S. Sacramento, Joana Sebastião, Joana |
author_role |
author |
author2 |
Maia, Hernâni L. S. Monteiro, Luís S. Sacramento, Joana Sebastião, Joana |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Ferreira, Paula M. T. Maia, Hernâni L. S. Monteiro, Luís S. Sacramento, Joana Sebastião, Joana |
dc.subject.por.fl_str_mv |
Science & Technology |
topic |
Science & Technology |
description |
Several b-substituted alanines are synthesised in high yields by a Michael addition of nucleophiles to N-acyl,N-tert-butyloxycarbonyl-dehydroalanine methyl ester, using mild reaction conditions and simple work-up procedures. The same method can be applied to dipeptides containing dehydroalanine. |
publishDate |
2000 |
dc.date.none.fl_str_mv |
2000 2000-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1822/2187 |
url |
https://hdl.handle.net/1822/2187 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
“Journal of the chemical society. Perkin transactions”. 1 (2000) 3317-3324. 1470-4358 10.1039/b003353g |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Royal Society of Chemistry |
publisher.none.fl_str_mv |
Royal Society of Chemistry |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799132196394500096 |