Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers

Detalhes bibliográficos
Autor(a) principal: Figueiredo, Lígia
Data de Publicação: 2015
Outros Autores: Moura, Carla, Pinto, Luís F. V., Ferreira, Frederico Castelo, Rodrigues, Alexandra
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.21/6091
Resumo: In this work, plasticizer agents were incorporated in a chitosan based formulation, as a strategy to improve the fragile structure of chitosan based-materials. Three different plasticizers: ethylene glycol, glycerol and sorbitol, were blended with chitosan to prepare 3D dense chitosan specimens. The properties of the obtained structures were assessed for mechanical, microstructural, physical and biocompatibility behavior. The results obtained revealed that from the different specimens prepared, the blend of chitosan with glycerol has superior mechanical properties and good biological behavior, making this chitosan based formulation a good candidate to improve robust chitosan structures for the construction of bioabsorbable orthopedic implants.
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spelling Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizersChitosanBioabsorbable implantsPlasticizersMechanical propertiesCitotocicityIn this work, plasticizer agents were incorporated in a chitosan based formulation, as a strategy to improve the fragile structure of chitosan based-materials. Three different plasticizers: ethylene glycol, glycerol and sorbitol, were blended with chitosan to prepare 3D dense chitosan specimens. The properties of the obtained structures were assessed for mechanical, microstructural, physical and biocompatibility behavior. The results obtained revealed that from the different specimens prepared, the blend of chitosan with glycerol has superior mechanical properties and good biological behavior, making this chitosan based formulation a good candidate to improve robust chitosan structures for the construction of bioabsorbable orthopedic implants.Elsevier Science BVRCIPLFigueiredo, LígiaMoura, CarlaPinto, Luís F. V.Ferreira, Frederico CasteloRodrigues, Alexandra2016-04-26T16:01:59Z2015-07-192015-07-19T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.21/6091engFIGUEIREDO, Lígia; [et al] - Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers. Procedia Engineering. ISSN 1877-7058. Vol. 110 (2015), pp. 175-1821877-705810.1016/j.proeng.2015.06.182info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T09:50:27Zoai:repositorio.ipl.pt:10400.21/6091Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:15:17.705176Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers
title Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers
spellingShingle Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers
Figueiredo, Lígia
Chitosan
Bioabsorbable implants
Plasticizers
Mechanical properties
Citotocicity
title_short Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers
title_full Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers
title_fullStr Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers
title_full_unstemmed Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers
title_sort Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers
author Figueiredo, Lígia
author_facet Figueiredo, Lígia
Moura, Carla
Pinto, Luís F. V.
Ferreira, Frederico Castelo
Rodrigues, Alexandra
author_role author
author2 Moura, Carla
Pinto, Luís F. V.
Ferreira, Frederico Castelo
Rodrigues, Alexandra
author2_role author
author
author
author
dc.contributor.none.fl_str_mv RCIPL
dc.contributor.author.fl_str_mv Figueiredo, Lígia
Moura, Carla
Pinto, Luís F. V.
Ferreira, Frederico Castelo
Rodrigues, Alexandra
dc.subject.por.fl_str_mv Chitosan
Bioabsorbable implants
Plasticizers
Mechanical properties
Citotocicity
topic Chitosan
Bioabsorbable implants
Plasticizers
Mechanical properties
Citotocicity
description In this work, plasticizer agents were incorporated in a chitosan based formulation, as a strategy to improve the fragile structure of chitosan based-materials. Three different plasticizers: ethylene glycol, glycerol and sorbitol, were blended with chitosan to prepare 3D dense chitosan specimens. The properties of the obtained structures were assessed for mechanical, microstructural, physical and biocompatibility behavior. The results obtained revealed that from the different specimens prepared, the blend of chitosan with glycerol has superior mechanical properties and good biological behavior, making this chitosan based formulation a good candidate to improve robust chitosan structures for the construction of bioabsorbable orthopedic implants.
publishDate 2015
dc.date.none.fl_str_mv 2015-07-19
2015-07-19T00:00:00Z
2016-04-26T16:01:59Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/6091
url http://hdl.handle.net/10400.21/6091
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv FIGUEIREDO, Lígia; [et al] - Processing and characterization of 3D dense chitosan pieces, for orthopedic applications, by adding plasticizers. Procedia Engineering. ISSN 1877-7058. Vol. 110 (2015), pp. 175-182
1877-7058
10.1016/j.proeng.2015.06.182
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier Science BV
publisher.none.fl_str_mv Elsevier Science BV
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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