One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/71582 |
Resumo: | Neat and hybrid poly(2-pyrrolidone), i.e. polyamide 4 (PA4) microparticles containing magnetic or conductive metal, metal oxide, or carbon nanotube fillers were prepared via environmentally-friendly solventless activated ring-opening polymerization of 2-pyrrolidone at 40 C. The method produces high porosity microparticles with diameters of 5e12mm and conversion to PA4 of 56e65%. Their structure and properties were characterized by light- and electron microscopy, thermal, spectral and X-ray diffraction techniques. Two crystalline polymorphs, namelya andb PА4, were found to coexist at room temperature by X-ray diffraction. The assessment of the adsorption capacity of the PA4 hybrid microparticles toward model protein showed up to 60% efficiency only after 1 h of incubation without any preliminary activation or functionalization. |
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One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilizationPolyamide 42-PyrrolidoneAnionic ring-opening polymerizationMagnetic microparticlesProtein carriersScience & TechnologyNeat and hybrid poly(2-pyrrolidone), i.e. polyamide 4 (PA4) microparticles containing magnetic or conductive metal, metal oxide, or carbon nanotube fillers were prepared via environmentally-friendly solventless activated ring-opening polymerization of 2-pyrrolidone at 40 C. The method produces high porosity microparticles with diameters of 5e12mm and conversion to PA4 of 56e65%. Their structure and properties were characterized by light- and electron microscopy, thermal, spectral and X-ray diffraction techniques. Two crystalline polymorphs, namelya andb PА4, were found to coexist at room temperature by X-ray diffraction. The assessment of the adsorption capacity of the PA4 hybrid microparticles toward model protein showed up to 60% efficiency only after 1 h of incubation without any preliminary activation or functionalization.The authors gratefully acknowledge the financial support of the project TSSiPRO NORTE-01-0145-FEDER-000015, supported by the regional operation program NORTE2020, under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund, as well as funding from FCT – Portuguese Foundation for Science and Technology within the strategic projects UID/CTM/50025/2013 and LA25/2013–2014. ZZD is thankful to FCT for the SFRH/BSAB/130271/2017 personal research grant.ElsevierUniversidade do MinhoDencheva, Nadya VasilevaBraz, Joana Filipa BarrosNunes, Teresa G.Oliveira, Filipa D.Denchev, Z.20182018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/71582eng0272-83971548-056910.1016/j.polymer.2018.04.080https://www.sciencedirect.com/science/article/pii/S0032386118303835info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:16:46Zoai:repositorium.sdum.uminho.pt:1822/71582Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:09:23.326589Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization |
title |
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization |
spellingShingle |
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization Dencheva, Nadya Vasileva Polyamide 4 2-Pyrrolidone Anionic ring-opening polymerization Magnetic microparticles Protein carriers Science & Technology |
title_short |
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization |
title_full |
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization |
title_fullStr |
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization |
title_full_unstemmed |
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization |
title_sort |
One-pot low temperature synthesis and characterization of hybrid poly(2-pyrrolidone) microparticles suitable for protein immobilization |
author |
Dencheva, Nadya Vasileva |
author_facet |
Dencheva, Nadya Vasileva Braz, Joana Filipa Barros Nunes, Teresa G. Oliveira, Filipa D. Denchev, Z. |
author_role |
author |
author2 |
Braz, Joana Filipa Barros Nunes, Teresa G. Oliveira, Filipa D. Denchev, Z. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Dencheva, Nadya Vasileva Braz, Joana Filipa Barros Nunes, Teresa G. Oliveira, Filipa D. Denchev, Z. |
dc.subject.por.fl_str_mv |
Polyamide 4 2-Pyrrolidone Anionic ring-opening polymerization Magnetic microparticles Protein carriers Science & Technology |
topic |
Polyamide 4 2-Pyrrolidone Anionic ring-opening polymerization Magnetic microparticles Protein carriers Science & Technology |
description |
Neat and hybrid poly(2-pyrrolidone), i.e. polyamide 4 (PA4) microparticles containing magnetic or conductive metal, metal oxide, or carbon nanotube fillers were prepared via environmentally-friendly solventless activated ring-opening polymerization of 2-pyrrolidone at 40 C. The method produces high porosity microparticles with diameters of 5e12mm and conversion to PA4 of 56e65%. Their structure and properties were characterized by light- and electron microscopy, thermal, spectral and X-ray diffraction techniques. Two crystalline polymorphs, namelya andb PА4, were found to coexist at room temperature by X-ray diffraction. The assessment of the adsorption capacity of the PA4 hybrid microparticles toward model protein showed up to 60% efficiency only after 1 h of incubation without any preliminary activation or functionalization. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018 2018-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/71582 |
url |
http://hdl.handle.net/1822/71582 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0272-8397 1548-0569 10.1016/j.polymer.2018.04.080 https://www.sciencedirect.com/science/article/pii/S0032386118303835 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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