Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models

Detalhes bibliográficos
Autor(a) principal: Mó, Inês
Data de Publicação: 2020
Outros Autores: Alves, Cátia, Diogo, Duarte de Melo, Sousa, Rita Lima, Correia, I.J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.6/10486
Resumo: Combinatorial cancer therapies mediated by nanomaterials can potentially overcome the limitations of conventional treatments. These therapies are generally investigated using 2D in vitro cancer models, leading to an inaccurate screening. Recently, 3D in vitro spheroids have emerged in the pre-clinical testing stage of nanomedicines due to their ability to mimic key features of the in vivo solid tumors.
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spelling Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer ModelsCancerChemotherapyNanoparticlesPhotothermal therapySpheroidsCombinatorial cancer therapies mediated by nanomaterials can potentially overcome the limitations of conventional treatments. These therapies are generally investigated using 2D in vitro cancer models, leading to an inaccurate screening. Recently, 3D in vitro spheroids have emerged in the pre-clinical testing stage of nanomedicines due to their ability to mimic key features of the in vivo solid tumors.CENTRO-01-0145-FEDER-028989; POCI-01- 0145-FEDER-031462; POCI-01-0145-FEDER-007491WileyuBibliorumMó, InêsAlves, CátiaDiogo, Duarte de MeloSousa, Rita LimaCorreia, I.J.2022-10-15T00:30:22Z2020-10-152020-10-15T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/10486eng10.1002/biot.202000219info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-15T09:52:22Zoai:ubibliorum.ubi.pt:10400.6/10486Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:50:25.862708Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models
title Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models
spellingShingle Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models
Mó, Inês
Cancer
Chemotherapy
Nanoparticles
Photothermal therapy
Spheroids
title_short Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models
title_full Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models
title_fullStr Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models
title_full_unstemmed Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models
title_sort Assessing the Combinatorial Chemo‐Photothermal Therapy Mediated by Sulfobetaine Methacrylate‐Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models
author Mó, Inês
author_facet Mó, Inês
Alves, Cátia
Diogo, Duarte de Melo
Sousa, Rita Lima
Correia, I.J.
author_role author
author2 Alves, Cátia
Diogo, Duarte de Melo
Sousa, Rita Lima
Correia, I.J.
author2_role author
author
author
author
dc.contributor.none.fl_str_mv uBibliorum
dc.contributor.author.fl_str_mv Mó, Inês
Alves, Cátia
Diogo, Duarte de Melo
Sousa, Rita Lima
Correia, I.J.
dc.subject.por.fl_str_mv Cancer
Chemotherapy
Nanoparticles
Photothermal therapy
Spheroids
topic Cancer
Chemotherapy
Nanoparticles
Photothermal therapy
Spheroids
description Combinatorial cancer therapies mediated by nanomaterials can potentially overcome the limitations of conventional treatments. These therapies are generally investigated using 2D in vitro cancer models, leading to an inaccurate screening. Recently, 3D in vitro spheroids have emerged in the pre-clinical testing stage of nanomedicines due to their ability to mimic key features of the in vivo solid tumors.
publishDate 2020
dc.date.none.fl_str_mv 2020-10-15
2020-10-15T00:00:00Z
2022-10-15T00:30:22Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.6/10486
url http://hdl.handle.net/10400.6/10486
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1002/biot.202000219
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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