Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks

Detalhes bibliográficos
Autor(a) principal: Patarra, João
Data de Publicação: 2009
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.1/336
Resumo: Dissertação mest., Engenharia Biológica, Universidade do Algarve, 2009
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spelling Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaksTesesAntioxidantesSobreiroAlfarrobeiraAplicações na medicinaSaúdeDieta mediterrânicaDissertação mest., Engenharia Biológica, Universidade do Algarve, 2009In this work it was determined the antioxidant, neuroprotective and anti-hyperglycemic activity of methanol (MeOH), hexane and water extracts made from two species of Mediterranean oaks, Quercus suber L. (cork oak) and Quercus ilex L. (holm oak), and Ceratonia siliqua L. (carob tree). Additionally, a phytochemical evaluation was made. The extracts were made from different organs or products namely leaves, fruits, pulps, germ flour, gum and stem bark from carob tree and leaves and acorns from Quercus species. Samples were collected from mature trees growing in the Algarve. Acorns from cork oak were also sampled in Alentejo, to check for the influence of geographic origin on the biological activities of the extracts. Moreover, a thermal treatment (‘dry roasting’) at 200 ºC was applied to a part of the acorn samples, and compared to the results obtained in samples dried at 50 ºC. The chemical profile varied in all the parameters, the MeOH extracts were richer in phenolic compounds, which were present in higher amounts in leaves (Quercus species), and in leaves and stem bark (carob tree). Acorns had a considerable amount of phenolics and lipids. There was a great variation in the major compound between samples. Methanol extracts from leaves, acorns and stem bark exhibited an interesting antioxidant activity. The leaf extracts from the two species had a high inhibitory activity against acetylcholinesterase and butyrylcholinesterase. The extracts had no relevant activity against α-amylase, but a potent inhibitory activity on α-glucosidase from baker’s yeast. Altogether, these results indicate that leaves and stem bark from carob tree, and acorns from cork oak and holm oak have bioactive compounds useful in the prevention/treatment of the above mentioned disorders. Further research is needed in order to identify the bioactive compounds, trough a bio-guided fractioning of the extracts.Romano, AnabelaCustódio, Luísa Margarida BatistaSapientiaPatarra, João2011-09-07T16:04:28Z20092009-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfapplication/pdfhttp://hdl.handle.net/10400.1/336eng579 PAT*Eva Caveinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:11:05Zoai:sapientia.ualg.pt:10400.1/336Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:54:42.290904Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks
title Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks
spellingShingle Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks
Patarra, João
Teses
Antioxidantes
Sobreiro
Alfarrobeira
Aplicações na medicina
Saúde
Dieta mediterrânica
title_short Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks
title_full Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks
title_fullStr Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks
title_full_unstemmed Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks
title_sort Evaluation of the in vitro biological activities of extracts from carob tree and mediterranean oaks
author Patarra, João
author_facet Patarra, João
author_role author
dc.contributor.none.fl_str_mv Romano, Anabela
Custódio, Luísa Margarida Batista
Sapientia
dc.contributor.author.fl_str_mv Patarra, João
dc.subject.por.fl_str_mv Teses
Antioxidantes
Sobreiro
Alfarrobeira
Aplicações na medicina
Saúde
Dieta mediterrânica
topic Teses
Antioxidantes
Sobreiro
Alfarrobeira
Aplicações na medicina
Saúde
Dieta mediterrânica
description Dissertação mest., Engenharia Biológica, Universidade do Algarve, 2009
publishDate 2009
dc.date.none.fl_str_mv 2009
2009-01-01T00:00:00Z
2011-09-07T16:04:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.1/336
url http://hdl.handle.net/10400.1/336
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 579 PAT*Eva Cave
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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