An artificial CO-releasing metalloprotein built by histidine-selective metallation

Detalhes bibliográficos
Autor(a) principal: Albuquerque, Inês S.
Data de Publicação: 2015
Outros Autores: Jeremias, Hélia F., Chaves-Ferreira, Miguel, Matak-Vinkovic, Dijana, Boutureira, Omar, Romão, Carlos C., Bernardes, Gonçalo J. L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/53200
Resumo: This journal is © The Royal Society of Chemistry 2015. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.
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spelling An artificial CO-releasing metalloprotein built by histidine-selective metallationThis journal is © The Royal Society of Chemistry 2015. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.We report the design and synthesis of an aquacarbonyl Ru(II) dication cis-[Ru(CO)2(H2O)4](2+) reagent for histidine (His)-selective metallation of interleukin (IL)-8 at site 33. The artificial, non-toxic interleukin (IL)-8-Ru(II)(CO)2 metalloprotein retained IL-8-dependent neutrophil chemotactic activity and was shown to spontaneously release CO in live cells.Royal Society of ChemistryRepositório da Universidade de LisboaAlbuquerque, Inês S.Jeremias, Hélia F.Chaves-Ferreira, MiguelMatak-Vinkovic, DijanaBoutureira, OmarRomão, Carlos C.Bernardes, Gonçalo J. L.2022-05-26T16:55:19Z20152015-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/53200engChem Commun (Camb). 2015 Mar 7;51(19):3993-39961359-734510.1039/C4CC10204E1364-548Xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:58:52Zoai:repositorio.ul.pt:10451/53200Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:04:09.799346Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv An artificial CO-releasing metalloprotein built by histidine-selective metallation
title An artificial CO-releasing metalloprotein built by histidine-selective metallation
spellingShingle An artificial CO-releasing metalloprotein built by histidine-selective metallation
Albuquerque, Inês S.
title_short An artificial CO-releasing metalloprotein built by histidine-selective metallation
title_full An artificial CO-releasing metalloprotein built by histidine-selective metallation
title_fullStr An artificial CO-releasing metalloprotein built by histidine-selective metallation
title_full_unstemmed An artificial CO-releasing metalloprotein built by histidine-selective metallation
title_sort An artificial CO-releasing metalloprotein built by histidine-selective metallation
author Albuquerque, Inês S.
author_facet Albuquerque, Inês S.
Jeremias, Hélia F.
Chaves-Ferreira, Miguel
Matak-Vinkovic, Dijana
Boutureira, Omar
Romão, Carlos C.
Bernardes, Gonçalo J. L.
author_role author
author2 Jeremias, Hélia F.
Chaves-Ferreira, Miguel
Matak-Vinkovic, Dijana
Boutureira, Omar
Romão, Carlos C.
Bernardes, Gonçalo J. L.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Albuquerque, Inês S.
Jeremias, Hélia F.
Chaves-Ferreira, Miguel
Matak-Vinkovic, Dijana
Boutureira, Omar
Romão, Carlos C.
Bernardes, Gonçalo J. L.
description This journal is © The Royal Society of Chemistry 2015. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.
publishDate 2015
dc.date.none.fl_str_mv 2015
2015-01-01T00:00:00Z
2022-05-26T16:55:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/53200
url http://hdl.handle.net/10451/53200
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Chem Commun (Camb). 2015 Mar 7;51(19):3993-3996
1359-7345
10.1039/C4CC10204E
1364-548X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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