Moderate to severe psoriasis treatment challenges through the era of biological drugs

Detalhes bibliográficos
Autor(a) principal: Vide,Júlia
Data de Publicação: 2017
Outros Autores: Magina,Sofia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500668
Resumo: Abstract: Biological therapy has revolutionized moderate to severe psoriasis treatment. However, despite being more effective than conventional systemic treatments, some patients do not respond or lose response to biotechnological treatments or develop drug-antibodies, interfering with its safety and efficacy. There are also clinical forms of the disease and patient profiles for which is pending further scientific evidence for more sustained therapeutic interventions. The continuous and more detailed knowledge of psoriasis pathophysiology has allowed identifying new therapeutic targets, which is expected to help overcome the challenges of individualized psoriasis treatment.
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spelling Moderate to severe psoriasis treatment challenges through the era of biological drugsBiological factorsBiological therapyBiological treatmentClinical trials as topicPsoriasisTherapies, investigationalAbstract: Biological therapy has revolutionized moderate to severe psoriasis treatment. However, despite being more effective than conventional systemic treatments, some patients do not respond or lose response to biotechnological treatments or develop drug-antibodies, interfering with its safety and efficacy. There are also clinical forms of the disease and patient profiles for which is pending further scientific evidence for more sustained therapeutic interventions. The continuous and more detailed knowledge of psoriasis pathophysiology has allowed identifying new therapeutic targets, which is expected to help overcome the challenges of individualized psoriasis treatment.Sociedade Brasileira de Dermatologia2017-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500668Anais Brasileiros de Dermatologia v.92 n.5 2017reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20175603info:eu-repo/semantics/openAccessVide,JúliaMagina,Sofiaeng2017-11-14T00:00:00Zoai:scielo:S0365-05962017000500668Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2017-11-14T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Moderate to severe psoriasis treatment challenges through the era of biological drugs
title Moderate to severe psoriasis treatment challenges through the era of biological drugs
spellingShingle Moderate to severe psoriasis treatment challenges through the era of biological drugs
Vide,Júlia
Biological factors
Biological therapy
Biological treatment
Clinical trials as topic
Psoriasis
Therapies, investigational
title_short Moderate to severe psoriasis treatment challenges through the era of biological drugs
title_full Moderate to severe psoriasis treatment challenges through the era of biological drugs
title_fullStr Moderate to severe psoriasis treatment challenges through the era of biological drugs
title_full_unstemmed Moderate to severe psoriasis treatment challenges through the era of biological drugs
title_sort Moderate to severe psoriasis treatment challenges through the era of biological drugs
author Vide,Júlia
author_facet Vide,Júlia
Magina,Sofia
author_role author
author2 Magina,Sofia
author2_role author
dc.contributor.author.fl_str_mv Vide,Júlia
Magina,Sofia
dc.subject.por.fl_str_mv Biological factors
Biological therapy
Biological treatment
Clinical trials as topic
Psoriasis
Therapies, investigational
topic Biological factors
Biological therapy
Biological treatment
Clinical trials as topic
Psoriasis
Therapies, investigational
description Abstract: Biological therapy has revolutionized moderate to severe psoriasis treatment. However, despite being more effective than conventional systemic treatments, some patients do not respond or lose response to biotechnological treatments or develop drug-antibodies, interfering with its safety and efficacy. There are also clinical forms of the disease and patient profiles for which is pending further scientific evidence for more sustained therapeutic interventions. The continuous and more detailed knowledge of psoriasis pathophysiology has allowed identifying new therapeutic targets, which is expected to help overcome the challenges of individualized psoriasis treatment.
publishDate 2017
dc.date.none.fl_str_mv 2017-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500668
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962017000500668
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/abd1806-4841.20175603
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.92 n.5 2017
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
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institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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