Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Anais brasileiros de dermatologia (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104 |
Resumo: | Around 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identification and culture on Agar and Lowenstein-Jensen medium base. A 41-year-old female with MCTD (LES predominance) is reported, presenting painless nodules in the right forearm. She denied local trauma. Immunosuppressed with prednisone and cyclophosphamide for 24 months. Lesion biopsy has demonstrated positive bacilloscopy (Ziehl-Neelsen stain) and M.chelonae in culture (Lowenstein-Jensen medium base), therefore clarithromycin treatment has been started (best therapy choice in the literature). |
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Anais brasileiros de dermatologia (Online) |
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Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue diseaseClarithromycinImmunosuppressionMixed connective tissue diseaseMycobacterium chelonaeMycobacterium fortuitumNontuberculous mycobacteriaPrednisoneSkinVirulenceAround 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identification and culture on Agar and Lowenstein-Jensen medium base. A 41-year-old female with MCTD (LES predominance) is reported, presenting painless nodules in the right forearm. She denied local trauma. Immunosuppressed with prednisone and cyclophosphamide for 24 months. Lesion biopsy has demonstrated positive bacilloscopy (Ziehl-Neelsen stain) and M.chelonae in culture (Lowenstein-Jensen medium base), therefore clarithromycin treatment has been started (best therapy choice in the literature).Sociedade Brasileira de Dermatologia2015-02-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104Anais Brasileiros de Dermatologia v.90 n.1 2015reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/abd1806-4841.20152276info:eu-repo/semantics/openAccessLage,RenanBiccigo,Danilo Guerreiro ZeoloSantos,Felipe Borba CalixtoChimara,EricaPereira,Elisangela Samartin PegasCosta,Adilson daeng2015-02-03T00:00:00Zoai:scielo:S0365-05962015000100104Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2015-02-03T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false |
dc.title.none.fl_str_mv |
Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
title |
Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
spellingShingle |
Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease Lage,Renan Clarithromycin Immunosuppression Mixed connective tissue disease Mycobacterium chelonae Mycobacterium fortuitum Nontuberculous mycobacteria Prednisone Skin Virulence |
title_short |
Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
title_full |
Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
title_fullStr |
Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
title_full_unstemmed |
Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
title_sort |
Mycobacterium chelonae cutaneous infection in a patient with mixed connective tissue disease |
author |
Lage,Renan |
author_facet |
Lage,Renan Biccigo,Danilo Guerreiro Zeolo Santos,Felipe Borba Calixto Chimara,Erica Pereira,Elisangela Samartin Pegas Costa,Adilson da |
author_role |
author |
author2 |
Biccigo,Danilo Guerreiro Zeolo Santos,Felipe Borba Calixto Chimara,Erica Pereira,Elisangela Samartin Pegas Costa,Adilson da |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Lage,Renan Biccigo,Danilo Guerreiro Zeolo Santos,Felipe Borba Calixto Chimara,Erica Pereira,Elisangela Samartin Pegas Costa,Adilson da |
dc.subject.por.fl_str_mv |
Clarithromycin Immunosuppression Mixed connective tissue disease Mycobacterium chelonae Mycobacterium fortuitum Nontuberculous mycobacteria Prednisone Skin Virulence |
topic |
Clarithromycin Immunosuppression Mixed connective tissue disease Mycobacterium chelonae Mycobacterium fortuitum Nontuberculous mycobacteria Prednisone Skin Virulence |
description |
Around 50 mycobacteria species cause human disease. Immunosuppressive states predispose to non-tuberculous mycobaterium infection, such as Mycobacterium chelonae: AFB, non-tuberculous, fast growth of low virulence and uncommon as a human pathogen. It may compromise the skin and soft tissues, lungs, lymph nodes and there is also a disseminated presentation. The diagnosis involves AFB identification and culture on Agar and Lowenstein-Jensen medium base. A 41-year-old female with MCTD (LES predominance) is reported, presenting painless nodules in the right forearm. She denied local trauma. Immunosuppressed with prednisone and cyclophosphamide for 24 months. Lesion biopsy has demonstrated positive bacilloscopy (Ziehl-Neelsen stain) and M.chelonae in culture (Lowenstein-Jensen medium base), therefore clarithromycin treatment has been started (best therapy choice in the literature). |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000100104 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/abd1806-4841.20152276 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Dermatologia |
dc.source.none.fl_str_mv |
Anais Brasileiros de Dermatologia v.90 n.1 2015 reponame:Anais brasileiros de dermatologia (Online) instname:Sociedade Brasileira de Dermatologia (SBD) instacron:SBD |
instname_str |
Sociedade Brasileira de Dermatologia (SBD) |
instacron_str |
SBD |
institution |
SBD |
reponame_str |
Anais brasileiros de dermatologia (Online) |
collection |
Anais brasileiros de dermatologia (Online) |
repository.name.fl_str_mv |
Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD) |
repository.mail.fl_str_mv |
abd@sbd.org.br||revista@sbd.org.br |
_version_ |
1752126420199407616 |