Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs

Detalhes bibliográficos
Autor(a) principal: Travassos,Ana Rita
Data de Publicação: 2012
Outros Autores: Borges-Costa,João, Raposo,João, Almeida,Luís Soares, Filipe,Paulo
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000500018
Resumo: The presence of granulomas in the skin of T-cell lymphoma patients is a rare but well-known phenomenon. The authors present the case of a 44-year-old Caucasian male, with a previously treated peripheral T-cell lymphoma, with cutaneous infiltration and extensive dyschromia on his lower limbs. Skin biopsies revealed the presence of sarcoid granulomas associated with the recurrence of the lymphoma, confirmed by immunostaining and molecular analysis. Although a new scheme of chemotherapy was started, he died 18 months later. There are two different patterns of skin granulomas associated with lymphoma: granulomatous infiltrates admixed with neoplastic cells and cutaneous granulomas constituting a nonspecific manifestation of the underlying lymphoma, but presently there is no evidence supporting their relationship with lymphoma prognosis.
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spelling Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbsGranulomaLymphoma, T-Cell, peripheralRecurrenceThe presence of granulomas in the skin of T-cell lymphoma patients is a rare but well-known phenomenon. The authors present the case of a 44-year-old Caucasian male, with a previously treated peripheral T-cell lymphoma, with cutaneous infiltration and extensive dyschromia on his lower limbs. Skin biopsies revealed the presence of sarcoid granulomas associated with the recurrence of the lymphoma, confirmed by immunostaining and molecular analysis. Although a new scheme of chemotherapy was started, he died 18 months later. There are two different patterns of skin granulomas associated with lymphoma: granulomatous infiltrates admixed with neoplastic cells and cutaneous granulomas constituting a nonspecific manifestation of the underlying lymphoma, but presently there is no evidence supporting their relationship with lymphoma prognosis.Sociedade Brasileira de Dermatologia2012-10-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000500018Anais Brasileiros de Dermatologia v.87 n.5 2012reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1590/S0365-05962012000500018info:eu-repo/semantics/openAccessTravassos,Ana RitaBorges-Costa,JoãoRaposo,JoãoAlmeida,Luís SoaresFilipe,Pauloeng2012-10-01T00:00:00Zoai:scielo:S0365-05962012000500018Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2012-10-01T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs
title Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs
spellingShingle Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs
Travassos,Ana Rita
Granuloma
Lymphoma, T-Cell, peripheral
Recurrence
title_short Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs
title_full Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs
title_fullStr Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs
title_full_unstemmed Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs
title_sort Recurrence of peripheral T-cell lymphoma as granulomas in the lower limbs
author Travassos,Ana Rita
author_facet Travassos,Ana Rita
Borges-Costa,João
Raposo,João
Almeida,Luís Soares
Filipe,Paulo
author_role author
author2 Borges-Costa,João
Raposo,João
Almeida,Luís Soares
Filipe,Paulo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Travassos,Ana Rita
Borges-Costa,João
Raposo,João
Almeida,Luís Soares
Filipe,Paulo
dc.subject.por.fl_str_mv Granuloma
Lymphoma, T-Cell, peripheral
Recurrence
topic Granuloma
Lymphoma, T-Cell, peripheral
Recurrence
description The presence of granulomas in the skin of T-cell lymphoma patients is a rare but well-known phenomenon. The authors present the case of a 44-year-old Caucasian male, with a previously treated peripheral T-cell lymphoma, with cutaneous infiltration and extensive dyschromia on his lower limbs. Skin biopsies revealed the presence of sarcoid granulomas associated with the recurrence of the lymphoma, confirmed by immunostaining and molecular analysis. Although a new scheme of chemotherapy was started, he died 18 months later. There are two different patterns of skin granulomas associated with lymphoma: granulomatous infiltrates admixed with neoplastic cells and cutaneous granulomas constituting a nonspecific manifestation of the underlying lymphoma, but presently there is no evidence supporting their relationship with lymphoma prognosis.
publishDate 2012
dc.date.none.fl_str_mv 2012-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000500018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000500018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0365-05962012000500018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.87 n.5 2012
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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