Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,

Detalhes bibliográficos
Autor(a) principal: Garcia,Lucas Campos
Data de Publicação: 2021
Outros Autores: Vale,Everton Carlos Siviero do, Ferrari,Maria de Lourdes, Faria,Lauro Damasceno de Carvalho
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000200228
Resumo: Abstract As the treatment of infectious and parasitic diseases improved, the prevalence of these conditions declined. However, with the expansion of the use of immunobiologicals, opportunistic infections have emerged, especially under atypical presentations. The present study reports the case of a patient treated with infliximab for Crohn's disease, who presented diarrhea, weight loss, abdominal pain, fever, and subcutaneous erythematous nodules that evolved with spontaneous fluctuation and ulceration. With the finding of alcohol-resistant bacilli and Mycobacterium tuberculosis DNA in a cutaneous fragment, through polymerase chain reaction, the diagnosis of gummatous tuberculosis was confirmed, probably secondary to hematogenous dissemination from an intestinal focus.
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spelling Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,Crohn's diseaseTumor Necrosis Factor Receptor-Associated Peptides and ProteinsMolecular target therapySkin tuberculosisAbstract As the treatment of infectious and parasitic diseases improved, the prevalence of these conditions declined. However, with the expansion of the use of immunobiologicals, opportunistic infections have emerged, especially under atypical presentations. The present study reports the case of a patient treated with infliximab for Crohn's disease, who presented diarrhea, weight loss, abdominal pain, fever, and subcutaneous erythematous nodules that evolved with spontaneous fluctuation and ulceration. With the finding of alcohol-resistant bacilli and Mycobacterium tuberculosis DNA in a cutaneous fragment, through polymerase chain reaction, the diagnosis of gummatous tuberculosis was confirmed, probably secondary to hematogenous dissemination from an intestinal focus.Sociedade Brasileira de Dermatologia2021-03-01info:eu-repo/semantics/reportinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000200228Anais Brasileiros de Dermatologia v.96 n.2 2021reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1016/j.abd.2020.07.008info:eu-repo/semantics/openAccessGarcia,Lucas CamposVale,Everton Carlos Siviero doFerrari,Maria de LourdesFaria,Lauro Damasceno de Carvalhoeng2021-05-04T00:00:00Zoai:scielo:S0365-05962021000200228Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2021-05-04T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
title Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
spellingShingle Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
Garcia,Lucas Campos
Crohn's disease
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Molecular target therapy
Skin tuberculosis
title_short Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
title_full Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
title_fullStr Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
title_full_unstemmed Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
title_sort Gummatous cutaneous tuberculosis associated with the use of infliximab for Crohn's disease,
author Garcia,Lucas Campos
author_facet Garcia,Lucas Campos
Vale,Everton Carlos Siviero do
Ferrari,Maria de Lourdes
Faria,Lauro Damasceno de Carvalho
author_role author
author2 Vale,Everton Carlos Siviero do
Ferrari,Maria de Lourdes
Faria,Lauro Damasceno de Carvalho
author2_role author
author
author
dc.contributor.author.fl_str_mv Garcia,Lucas Campos
Vale,Everton Carlos Siviero do
Ferrari,Maria de Lourdes
Faria,Lauro Damasceno de Carvalho
dc.subject.por.fl_str_mv Crohn's disease
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Molecular target therapy
Skin tuberculosis
topic Crohn's disease
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Molecular target therapy
Skin tuberculosis
description Abstract As the treatment of infectious and parasitic diseases improved, the prevalence of these conditions declined. However, with the expansion of the use of immunobiologicals, opportunistic infections have emerged, especially under atypical presentations. The present study reports the case of a patient treated with infliximab for Crohn's disease, who presented diarrhea, weight loss, abdominal pain, fever, and subcutaneous erythematous nodules that evolved with spontaneous fluctuation and ulceration. With the finding of alcohol-resistant bacilli and Mycobacterium tuberculosis DNA in a cutaneous fragment, through polymerase chain reaction, the diagnosis of gummatous tuberculosis was confirmed, probably secondary to hematogenous dissemination from an intestinal focus.
publishDate 2021
dc.date.none.fl_str_mv 2021-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000200228
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962021000200228
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.abd.2020.07.008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.96 n.2 2021
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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