Case for diagnosis. Radiotherapy-induced pemphigus vegetans

Detalhes bibliográficos
Autor(a) principal: Almeida Jr,Hiram Larangeira de
Data de Publicação: 2022
Outros Autores: Almeida,Antônia Larangeira de, Martinez,Pedro Henrique Evangelista, Boff,Ana Letícia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais brasileiros de dermatologia (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962022000300376
Resumo: Abstract A 73-year-old male patient developed a poorly differentiated squamous cell carcinoma in the anal canal nine months ago. He was treated with two cycles of 5-fluorouracil and cisplatin and concomitant radiotherapy (6 MeV linear photon accelerator, total dose of 54 Gy), with complete remission. Since forty-five days he presentes a painful perianal and intergluteal erosion with circinate pustular borders. Light microscopy showed pseudoepitheliomatous hyperplasia of the epidermis with microabscesses of inflammatory cells (neutrophils and eosinophils) and acantholytic keratinocytes . Indirect immunofluorescence was positive for IgG, with an intercellular pattern, 1:80 titer. The diagnosis of radiotherapy-induced pemphigus vegetans was established and there was significant regression with oral prednisone (40 mg) and topical betamethasone.
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spelling Case for diagnosis. Radiotherapy-induced pemphigus vegetansRadiotherapyPemphigus vegetansAbstract A 73-year-old male patient developed a poorly differentiated squamous cell carcinoma in the anal canal nine months ago. He was treated with two cycles of 5-fluorouracil and cisplatin and concomitant radiotherapy (6 MeV linear photon accelerator, total dose of 54 Gy), with complete remission. Since forty-five days he presentes a painful perianal and intergluteal erosion with circinate pustular borders. Light microscopy showed pseudoepitheliomatous hyperplasia of the epidermis with microabscesses of inflammatory cells (neutrophils and eosinophils) and acantholytic keratinocytes . Indirect immunofluorescence was positive for IgG, with an intercellular pattern, 1:80 titer. The diagnosis of radiotherapy-induced pemphigus vegetans was established and there was significant regression with oral prednisone (40 mg) and topical betamethasone.Sociedade Brasileira de Dermatologia2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962022000300376Anais Brasileiros de Dermatologia v.97 n.3 2022reponame:Anais brasileiros de dermatologia (Online)instname:Sociedade Brasileira de Dermatologia (SBD)instacron:SBD10.1016/j.abd.2021.09.005info:eu-repo/semantics/openAccessAlmeida Jr,Hiram Larangeira deAlmeida,Antônia Larangeira deMartinez,Pedro Henrique EvangelistaBoff,Ana Letíciaeng2022-06-10T00:00:00Zoai:scielo:S0365-05962022000300376Revistahttp://www.anaisdedermatologia.org.br/https://old.scielo.br/oai/scielo-oai.phpabd@sbd.org.br||revista@sbd.org.br1806-48410365-0596opendoar:2022-06-10T00:00Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)false
dc.title.none.fl_str_mv Case for diagnosis. Radiotherapy-induced pemphigus vegetans
title Case for diagnosis. Radiotherapy-induced pemphigus vegetans
spellingShingle Case for diagnosis. Radiotherapy-induced pemphigus vegetans
Almeida Jr,Hiram Larangeira de
Radiotherapy
Pemphigus vegetans
title_short Case for diagnosis. Radiotherapy-induced pemphigus vegetans
title_full Case for diagnosis. Radiotherapy-induced pemphigus vegetans
title_fullStr Case for diagnosis. Radiotherapy-induced pemphigus vegetans
title_full_unstemmed Case for diagnosis. Radiotherapy-induced pemphigus vegetans
title_sort Case for diagnosis. Radiotherapy-induced pemphigus vegetans
author Almeida Jr,Hiram Larangeira de
author_facet Almeida Jr,Hiram Larangeira de
Almeida,Antônia Larangeira de
Martinez,Pedro Henrique Evangelista
Boff,Ana Letícia
author_role author
author2 Almeida,Antônia Larangeira de
Martinez,Pedro Henrique Evangelista
Boff,Ana Letícia
author2_role author
author
author
dc.contributor.author.fl_str_mv Almeida Jr,Hiram Larangeira de
Almeida,Antônia Larangeira de
Martinez,Pedro Henrique Evangelista
Boff,Ana Letícia
dc.subject.por.fl_str_mv Radiotherapy
Pemphigus vegetans
topic Radiotherapy
Pemphigus vegetans
description Abstract A 73-year-old male patient developed a poorly differentiated squamous cell carcinoma in the anal canal nine months ago. He was treated with two cycles of 5-fluorouracil and cisplatin and concomitant radiotherapy (6 MeV linear photon accelerator, total dose of 54 Gy), with complete remission. Since forty-five days he presentes a painful perianal and intergluteal erosion with circinate pustular borders. Light microscopy showed pseudoepitheliomatous hyperplasia of the epidermis with microabscesses of inflammatory cells (neutrophils and eosinophils) and acantholytic keratinocytes . Indirect immunofluorescence was positive for IgG, with an intercellular pattern, 1:80 titer. The diagnosis of radiotherapy-induced pemphigus vegetans was established and there was significant regression with oral prednisone (40 mg) and topical betamethasone.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962022000300376
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962022000300376
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.abd.2021.09.005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv Anais Brasileiros de Dermatologia v.97 n.3 2022
reponame:Anais brasileiros de dermatologia (Online)
instname:Sociedade Brasileira de Dermatologia (SBD)
instacron:SBD
instname_str Sociedade Brasileira de Dermatologia (SBD)
instacron_str SBD
institution SBD
reponame_str Anais brasileiros de dermatologia (Online)
collection Anais brasileiros de dermatologia (Online)
repository.name.fl_str_mv Anais brasileiros de dermatologia (Online) - Sociedade Brasileira de Dermatologia (SBD)
repository.mail.fl_str_mv abd@sbd.org.br||revista@sbd.org.br
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