Multiple cavitary pulmonary nodules in association with pyoderma gangrenosum: case report

• Autor(a) principal: Bittencourt,Maraya de Jesus Semblano
• Data de Publicação: 2012
• Outros Autores: Soares,Luciana Fontenele Brito, Lobato,Lilia Sampaio, Mançano,Alexandre Dias, Leandro,Helandro Stuart Castro, Fonseca,Diana Mendes da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Anais brasileiros de dermatologia (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962012000200018
• topic: Cavitation; Multiple pulmonary nodules; Pyoderma gangrenosum; Wegener granulomatosis

Pyoderma gangrenosum is a rare neutrophilic disease of unknown origin that is associated with systemic diseases in 50% of cases. It is characterized by erythematous-violaceous nodular lesions that quickly progress to painful ulcers, with undermined edges, necrotic-hemorrhagic, varying in size and depth, located mainly in the lower limbs. Extracutaneous locations of pyoderma gangrenosum are rare, usually involving the lungs; the main differential diagnosis in these cases is Wegener granulomatosis. We report a case of pyoderma gangrenosum, which showed multiple cavitary lung nodules, with good response to high doses of steroids. Once excluded the possibility of Wegener granulomatosis, the authors concluded that it was the manifestation of systemic pyoderma gangrenosum with pulmonary involvement.