The aplication of cyanoacrilate surgical glue on skin suture in rats
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Cirúrgica Brasileira (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000100056 |
Resumo: | Abstract Purpose: To compare the use of a new cyanoacrylate-based surgical glue and suture with sepa-rate points in skin wounds closure. Methods: Thirty-six rats were subjected to a 4cm dorsal longitudinal incision. Twelve were sub-jected to simple suture with polyamide 6-0, 12 rats underwent wall synthesis using Dermabond(r) and 12 was performed cutaneous synthesis with N-2-Butyl-Cyanoacrylate. Twelve of each group was euthanized on the seventh postoperative day, their blood was taken to biochemical tests and a layer of skin and subcutaneous tissue surrounding the surgical scar was randomly divided in two segments, to the submission of tension tests and to histological study. Results: There were no significant difference between groups (p>0.05). In the soft dermis there was more type I collagen production in group I (p<0.05), group II and III was similar re-sults (p>0.05). In the compact dermis, all 3 groups showed similar results (p>0.05). The biomechanical study was similarity between the glue groups (p>0.05) but the group III proved to be different from the others having a higher resistance (p>0.05) . Conclusion: This glue does not cause any inflammation or kidney and hepatic toxicity. Polyamide sutures are more resistant and the glue should be used alone only in less tension are-as. |
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Acta Cirúrgica Brasileira (Online) |
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The aplication of cyanoacrilate surgical glue on skin suture in ratsCollagenWound HealingCyanoacrylatesRatsAbstract Purpose: To compare the use of a new cyanoacrylate-based surgical glue and suture with sepa-rate points in skin wounds closure. Methods: Thirty-six rats were subjected to a 4cm dorsal longitudinal incision. Twelve were sub-jected to simple suture with polyamide 6-0, 12 rats underwent wall synthesis using Dermabond(r) and 12 was performed cutaneous synthesis with N-2-Butyl-Cyanoacrylate. Twelve of each group was euthanized on the seventh postoperative day, their blood was taken to biochemical tests and a layer of skin and subcutaneous tissue surrounding the surgical scar was randomly divided in two segments, to the submission of tension tests and to histological study. Results: There were no significant difference between groups (p>0.05). In the soft dermis there was more type I collagen production in group I (p<0.05), group II and III was similar re-sults (p>0.05). In the compact dermis, all 3 groups showed similar results (p>0.05). The biomechanical study was similarity between the glue groups (p>0.05) but the group III proved to be different from the others having a higher resistance (p>0.05) . Conclusion: This glue does not cause any inflammation or kidney and hepatic toxicity. Polyamide sutures are more resistant and the glue should be used alone only in less tension are-as.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2017-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000100056Acta Cirúrgica Brasileira v.32 n.1 2017reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/s0102-865020170107info:eu-repo/semantics/openAccessIlgenfritz Neto,JoãoAydos,Ricardo DutraSilva,Iandara SchettertRamalho,Rondon TostaIlgenfritz Júnior,JoãoCampos,Gerson Gattats Orro deNakamura,Ricardo KenithiGuerisoli,Danilo M. ZanelloCantero,Wilson de Barroseng2017-02-14T00:00:00Zoai:scielo:S0102-86502017000100056Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2017-02-14T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false |
dc.title.none.fl_str_mv |
The aplication of cyanoacrilate surgical glue on skin suture in rats |
title |
The aplication of cyanoacrilate surgical glue on skin suture in rats |
spellingShingle |
The aplication of cyanoacrilate surgical glue on skin suture in rats Ilgenfritz Neto,João Collagen Wound Healing Cyanoacrylates Rats |
title_short |
The aplication of cyanoacrilate surgical glue on skin suture in rats |
title_full |
The aplication of cyanoacrilate surgical glue on skin suture in rats |
title_fullStr |
The aplication of cyanoacrilate surgical glue on skin suture in rats |
title_full_unstemmed |
The aplication of cyanoacrilate surgical glue on skin suture in rats |
title_sort |
The aplication of cyanoacrilate surgical glue on skin suture in rats |
author |
Ilgenfritz Neto,João |
author_facet |
Ilgenfritz Neto,João Aydos,Ricardo Dutra Silva,Iandara Schettert Ramalho,Rondon Tosta Ilgenfritz Júnior,João Campos,Gerson Gattats Orro de Nakamura,Ricardo Kenithi Guerisoli,Danilo M. Zanello Cantero,Wilson de Barros |
author_role |
author |
author2 |
Aydos,Ricardo Dutra Silva,Iandara Schettert Ramalho,Rondon Tosta Ilgenfritz Júnior,João Campos,Gerson Gattats Orro de Nakamura,Ricardo Kenithi Guerisoli,Danilo M. Zanello Cantero,Wilson de Barros |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Ilgenfritz Neto,João Aydos,Ricardo Dutra Silva,Iandara Schettert Ramalho,Rondon Tosta Ilgenfritz Júnior,João Campos,Gerson Gattats Orro de Nakamura,Ricardo Kenithi Guerisoli,Danilo M. Zanello Cantero,Wilson de Barros |
dc.subject.por.fl_str_mv |
Collagen Wound Healing Cyanoacrylates Rats |
topic |
Collagen Wound Healing Cyanoacrylates Rats |
description |
Abstract Purpose: To compare the use of a new cyanoacrylate-based surgical glue and suture with sepa-rate points in skin wounds closure. Methods: Thirty-six rats were subjected to a 4cm dorsal longitudinal incision. Twelve were sub-jected to simple suture with polyamide 6-0, 12 rats underwent wall synthesis using Dermabond(r) and 12 was performed cutaneous synthesis with N-2-Butyl-Cyanoacrylate. Twelve of each group was euthanized on the seventh postoperative day, their blood was taken to biochemical tests and a layer of skin and subcutaneous tissue surrounding the surgical scar was randomly divided in two segments, to the submission of tension tests and to histological study. Results: There were no significant difference between groups (p>0.05). In the soft dermis there was more type I collagen production in group I (p<0.05), group II and III was similar re-sults (p>0.05). In the compact dermis, all 3 groups showed similar results (p>0.05). The biomechanical study was similarity between the glue groups (p>0.05) but the group III proved to be different from the others having a higher resistance (p>0.05) . Conclusion: This glue does not cause any inflammation or kidney and hepatic toxicity. Polyamide sutures are more resistant and the glue should be used alone only in less tension are-as. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000100056 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502017000100056 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/s0102-865020170107 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
Acta Cirúrgica Brasileira v.32 n.1 2017 reponame:Acta Cirúrgica Brasileira (Online) instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC |
instname_str |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
instacron_str |
SBDPC |
institution |
SBDPC |
reponame_str |
Acta Cirúrgica Brasileira (Online) |
collection |
Acta Cirúrgica Brasileira (Online) |
repository.name.fl_str_mv |
Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) |
repository.mail.fl_str_mv |
||sgolden@terra.com.br |
_version_ |
1752126444105891840 |