Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam

Detalhes bibliográficos
Autor(a) principal: Botelho,Nara Macedo
Data de Publicação: 2013
Outros Autores: Corrêa,Suelen Costa, Lobato,Rodolfo Costa, Teixeira,Renan Kleber Costa, Quaresma,Juarez Antônio Simões
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300005
Resumo: PURPOSE: To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). METHODS: The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells. RESULTS: It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage). CONCLUSION: Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor.
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spelling Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsamCarcinoma 256, WalkerImmunohistochemistryCervix UteriRatsPURPOSE: To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). METHODS: The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells. RESULTS: It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage). CONCLUSION: Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor.Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2013-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300005Acta Cirúrgica Brasileira v.28 n.3 2013reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502013000300005info:eu-repo/semantics/openAccessBotelho,Nara MacedoCorrêa,Suelen CostaLobato,Rodolfo CostaTeixeira,Renan Kleber CostaQuaresma,Juarez Antônio Simõeseng2013-03-06T00:00:00Zoai:scielo:S0102-86502013000300005Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2013-03-06T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
title Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
spellingShingle Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
Botelho,Nara Macedo
Carcinoma 256, Walker
Immunohistochemistry
Cervix Uteri
Rats
title_short Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
title_full Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
title_fullStr Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
title_full_unstemmed Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
title_sort Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
author Botelho,Nara Macedo
author_facet Botelho,Nara Macedo
Corrêa,Suelen Costa
Lobato,Rodolfo Costa
Teixeira,Renan Kleber Costa
Quaresma,Juarez Antônio Simões
author_role author
author2 Corrêa,Suelen Costa
Lobato,Rodolfo Costa
Teixeira,Renan Kleber Costa
Quaresma,Juarez Antônio Simões
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Botelho,Nara Macedo
Corrêa,Suelen Costa
Lobato,Rodolfo Costa
Teixeira,Renan Kleber Costa
Quaresma,Juarez Antônio Simões
dc.subject.por.fl_str_mv Carcinoma 256, Walker
Immunohistochemistry
Cervix Uteri
Rats
topic Carcinoma 256, Walker
Immunohistochemistry
Cervix Uteri
Rats
description PURPOSE: To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). METHODS: The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells. RESULTS: It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage). CONCLUSION: Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor.
publishDate 2013
dc.date.none.fl_str_mv 2013-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502013000300005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502013000300005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.28 n.3 2013
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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