Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions
Autor(a) principal: | |
---|---|
Data de Publicação: | 2003 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Physics |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-97332003000300018 |
Resumo: | We review some results concerning the energetic and dynamical consequences of taking a generic hydrophobic model of a random polypeptide chain, where the effective hydrophobic interactions are represented by Hookean springs. Then we present a set of calculations on a microscopic model of hydrophobic interactions, investigating the behaviour of a hydrophobic chain in the vicinity of a hydrophobic boundary. We conclude with some speculations as to the thermodynamics of pre-biotic functions proteins may have discharged very early on in the evolutionary past. |
id |
SBF-2_ae433c31f5d203bd9ee5ed487a087114 |
---|---|
oai_identifier_str |
oai:scielo:S0103-97332003000300018 |
network_acronym_str |
SBF-2 |
network_name_str |
Brazilian Journal of Physics |
repository_id_str |
|
spelling |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactionsWe review some results concerning the energetic and dynamical consequences of taking a generic hydrophobic model of a random polypeptide chain, where the effective hydrophobic interactions are represented by Hookean springs. Then we present a set of calculations on a microscopic model of hydrophobic interactions, investigating the behaviour of a hydrophobic chain in the vicinity of a hydrophobic boundary. We conclude with some speculations as to the thermodynamics of pre-biotic functions proteins may have discharged very early on in the evolutionary past.Sociedade Brasileira de Física2003-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-97332003000300018Brazilian Journal of Physics v.33 n.3 2003reponame:Brazilian Journal of Physicsinstname:Sociedade Brasileira de Física (SBF)instacron:SBF10.1590/S0103-97332003000300018info:eu-repo/semantics/openAccessErzan,AyseTüzel,Erkaneng2003-11-14T00:00:00Zoai:scielo:S0103-97332003000300018Revistahttp://www.sbfisica.org.br/v1/home/index.php/pt/ONGhttps://old.scielo.br/oai/scielo-oai.phpsbfisica@sbfisica.org.br||sbfisica@sbfisica.org.br1678-44480103-9733opendoar:2003-11-14T00:00Brazilian Journal of Physics - Sociedade Brasileira de Física (SBF)false |
dc.title.none.fl_str_mv |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions |
title |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions |
spellingShingle |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions Erzan,Ayse |
title_short |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions |
title_full |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions |
title_fullStr |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions |
title_full_unstemmed |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions |
title_sort |
Hydrophobic models of protein folding and the thermodynamics of chain-boundary interactions |
author |
Erzan,Ayse |
author_facet |
Erzan,Ayse Tüzel,Erkan |
author_role |
author |
author2 |
Tüzel,Erkan |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Erzan,Ayse Tüzel,Erkan |
description |
We review some results concerning the energetic and dynamical consequences of taking a generic hydrophobic model of a random polypeptide chain, where the effective hydrophobic interactions are represented by Hookean springs. Then we present a set of calculations on a microscopic model of hydrophobic interactions, investigating the behaviour of a hydrophobic chain in the vicinity of a hydrophobic boundary. We conclude with some speculations as to the thermodynamics of pre-biotic functions proteins may have discharged very early on in the evolutionary past. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-97332003000300018 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-97332003000300018 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-97332003000300018 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Física |
publisher.none.fl_str_mv |
Sociedade Brasileira de Física |
dc.source.none.fl_str_mv |
Brazilian Journal of Physics v.33 n.3 2003 reponame:Brazilian Journal of Physics instname:Sociedade Brasileira de Física (SBF) instacron:SBF |
instname_str |
Sociedade Brasileira de Física (SBF) |
instacron_str |
SBF |
institution |
SBF |
reponame_str |
Brazilian Journal of Physics |
collection |
Brazilian Journal of Physics |
repository.name.fl_str_mv |
Brazilian Journal of Physics - Sociedade Brasileira de Física (SBF) |
repository.mail.fl_str_mv |
sbfisica@sbfisica.org.br||sbfisica@sbfisica.org.br |
_version_ |
1754734860422873088 |