Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure

Detalhes bibliográficos
Autor(a) principal: Gomes,Paulo C. F. de Lima
Data de Publicação: 2010
Outros Autores: D'Andrea,Éverton D., Mendes,Camila B., Siqueira,Maria Elisa P. B. de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000100018
Resumo: Analysis of unchanged toluene, benzene and n-hexane in human blood and urine can be useful to evaluate occupational exposure to these solvents. A simple method was developed using headspace-solid phase microextraction (HS-SPME) for simultaneous gas-chromatography analysis of toluene, benzene and n-hexane in urine and blood; with purpose of biological monitoring of occupational exposure. Carboxen/polidimethylsiloxane fiber (CAR-PDMS) and PDMS fiber coating were employed in this analysis. Blood and urine samples were collected from handling glue workers. The toluene was detected in all blood samples collected from workers handling glue in shoe repair shops, when using CAR-PDMS fibers (16.0-55.2 μg L-1, n=7). n-Hexane was only detected in two blood samples (33.0 and 41.3 μg L-1) and benzene was not detected in anyone. No solvent could be quantified in urine samples.
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spelling Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposureSPMEn-hexanetoluenebenzeneurinebloodAnalysis of unchanged toluene, benzene and n-hexane in human blood and urine can be useful to evaluate occupational exposure to these solvents. A simple method was developed using headspace-solid phase microextraction (HS-SPME) for simultaneous gas-chromatography analysis of toluene, benzene and n-hexane in urine and blood; with purpose of biological monitoring of occupational exposure. Carboxen/polidimethylsiloxane fiber (CAR-PDMS) and PDMS fiber coating were employed in this analysis. Blood and urine samples were collected from handling glue workers. The toluene was detected in all blood samples collected from workers handling glue in shoe repair shops, when using CAR-PDMS fibers (16.0-55.2 μg L-1, n=7). n-Hexane was only detected in two blood samples (33.0 and 41.3 μg L-1) and benzene was not detected in anyone. No solvent could be quantified in urine samples.Sociedade Brasileira de Química2010-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000100018Journal of the Brazilian Chemical Society v.21 n.1 2010reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532010000100018info:eu-repo/semantics/openAccessGomes,Paulo C. F. de LimaD'Andrea,Éverton D.Mendes,Camila B.Siqueira,Maria Elisa P. B. deeng2010-02-18T00:00:00Zoai:scielo:S0103-50532010000100018Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2010-02-18T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure
title Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure
spellingShingle Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure
Gomes,Paulo C. F. de Lima
SPME
n-hexane
toluene
benzene
urine
blood
title_short Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure
title_full Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure
title_fullStr Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure
title_full_unstemmed Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure
title_sort Determination of benzene, toluene and N-hexane in urine and blood by headspace solid-phase microextration/gas-chromatography for the biomonitoring of occupational exposure
author Gomes,Paulo C. F. de Lima
author_facet Gomes,Paulo C. F. de Lima
D'Andrea,Éverton D.
Mendes,Camila B.
Siqueira,Maria Elisa P. B. de
author_role author
author2 D'Andrea,Éverton D.
Mendes,Camila B.
Siqueira,Maria Elisa P. B. de
author2_role author
author
author
dc.contributor.author.fl_str_mv Gomes,Paulo C. F. de Lima
D'Andrea,Éverton D.
Mendes,Camila B.
Siqueira,Maria Elisa P. B. de
dc.subject.por.fl_str_mv SPME
n-hexane
toluene
benzene
urine
blood
topic SPME
n-hexane
toluene
benzene
urine
blood
description Analysis of unchanged toluene, benzene and n-hexane in human blood and urine can be useful to evaluate occupational exposure to these solvents. A simple method was developed using headspace-solid phase microextraction (HS-SPME) for simultaneous gas-chromatography analysis of toluene, benzene and n-hexane in urine and blood; with purpose of biological monitoring of occupational exposure. Carboxen/polidimethylsiloxane fiber (CAR-PDMS) and PDMS fiber coating were employed in this analysis. Blood and urine samples were collected from handling glue workers. The toluene was detected in all blood samples collected from workers handling glue in shoe repair shops, when using CAR-PDMS fibers (16.0-55.2 μg L-1, n=7). n-Hexane was only detected in two blood samples (33.0 and 41.3 μg L-1) and benzene was not detected in anyone. No solvent could be quantified in urine samples.
publishDate 2010
dc.date.none.fl_str_mv 2010-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000100018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532010000100018
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532010000100018
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.21 n.1 2010
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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