Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Zoologia (Curitiba. Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702020000100319 |
Resumo: | ABSTRACT Tannins are polyphenols that are present in various plants, and potentially contain antioxidant properties that promote reproduction in animals. This study investigated how tannic acid (TA) affects the reproductive parameters of male Brandt’s voles, Lasiopodomys brandtii (Radde, 1861). Specifically, the anti-oxidative level of serum, autophagy in the testis, and reproductive physiology were assessed in males treated with TA from the pubertal stage. Compared to the control, low dose TA enhanced relative testis and epididymis weight and sperm concentration in the epididymis, and significantly increased the level of serum superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px). mRNA levels of autophagy related genes LC3 and Beclin1 decreased significantly with low dose TA compared to the control. However, compared to the control, high dose TA sharply reduced the levels of serum SOD, GSH-Px, CAT, serum testosterone (T), and mRNA level in steroidogenic acute regulatory protein (StAR) in the testis. Both sperm abnormality and mortality increased with high dose TA compared to the control and low dose TA. Collectively, this study demonstrated that TA treatment during puberty had a dose-dependent effect on the reproductive responses of male Brandt’s voles. TA might mediate autophagy in the testis, through both indirect and direct processes. TA mainly affected the reproductive function of male Brandt’s voles by regulating anti-oxidative levels. This study advances our understanding of the mechanisms by which tannins influence reproduction in herbivores. |
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Zoologia (Curitiba. Online) |
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Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acidAntioxidativeautophagypubertyreproductionABSTRACT Tannins are polyphenols that are present in various plants, and potentially contain antioxidant properties that promote reproduction in animals. This study investigated how tannic acid (TA) affects the reproductive parameters of male Brandt’s voles, Lasiopodomys brandtii (Radde, 1861). Specifically, the anti-oxidative level of serum, autophagy in the testis, and reproductive physiology were assessed in males treated with TA from the pubertal stage. Compared to the control, low dose TA enhanced relative testis and epididymis weight and sperm concentration in the epididymis, and significantly increased the level of serum superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px). mRNA levels of autophagy related genes LC3 and Beclin1 decreased significantly with low dose TA compared to the control. However, compared to the control, high dose TA sharply reduced the levels of serum SOD, GSH-Px, CAT, serum testosterone (T), and mRNA level in steroidogenic acute regulatory protein (StAR) in the testis. Both sperm abnormality and mortality increased with high dose TA compared to the control and low dose TA. Collectively, this study demonstrated that TA treatment during puberty had a dose-dependent effect on the reproductive responses of male Brandt’s voles. TA might mediate autophagy in the testis, through both indirect and direct processes. TA mainly affected the reproductive function of male Brandt’s voles by regulating anti-oxidative levels. This study advances our understanding of the mechanisms by which tannins influence reproduction in herbivores.Sociedade Brasileira de Zoologia2020-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702020000100319Zoologia (Curitiba) v.37 2020reponame:Zoologia (Curitiba. Online)instname:Sociedade Brasileira de Zoologiainstacron:SBZ10.3897/zoologia.37.e52232info:eu-repo/semantics/openAccessDai,XinZhou,Ling-YuXu,Ting-TingWang,Qiu-YueLuo,BinLi,Yan-YuGu,ChenLi,Shi-PingWang,Ai-QinWei,Wan-HongYang,Sheng-Meieng2020-12-11T00:00:00Zoai:scielo:S1984-46702020000100319Revistahttp://www.scielo.br/zoolONGhttps://old.scielo.br/oai/scielo-oai.phpsbz@sbzoologia.org.br1984-46891984-4670opendoar:2020-12-11T00:00Zoologia (Curitiba. Online) - Sociedade Brasileira de Zoologiafalse |
dc.title.none.fl_str_mv |
Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid |
title |
Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid |
spellingShingle |
Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid Dai,Xin Antioxidative autophagy puberty reproduction |
title_short |
Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid |
title_full |
Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid |
title_fullStr |
Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid |
title_full_unstemmed |
Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid |
title_sort |
Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid |
author |
Dai,Xin |
author_facet |
Dai,Xin Zhou,Ling-Yu Xu,Ting-Ting Wang,Qiu-Yue Luo,Bin Li,Yan-Yu Gu,Chen Li,Shi-Ping Wang,Ai-Qin Wei,Wan-Hong Yang,Sheng-Mei |
author_role |
author |
author2 |
Zhou,Ling-Yu Xu,Ting-Ting Wang,Qiu-Yue Luo,Bin Li,Yan-Yu Gu,Chen Li,Shi-Ping Wang,Ai-Qin Wei,Wan-Hong Yang,Sheng-Mei |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Dai,Xin Zhou,Ling-Yu Xu,Ting-Ting Wang,Qiu-Yue Luo,Bin Li,Yan-Yu Gu,Chen Li,Shi-Ping Wang,Ai-Qin Wei,Wan-Hong Yang,Sheng-Mei |
dc.subject.por.fl_str_mv |
Antioxidative autophagy puberty reproduction |
topic |
Antioxidative autophagy puberty reproduction |
description |
ABSTRACT Tannins are polyphenols that are present in various plants, and potentially contain antioxidant properties that promote reproduction in animals. This study investigated how tannic acid (TA) affects the reproductive parameters of male Brandt’s voles, Lasiopodomys brandtii (Radde, 1861). Specifically, the anti-oxidative level of serum, autophagy in the testis, and reproductive physiology were assessed in males treated with TA from the pubertal stage. Compared to the control, low dose TA enhanced relative testis and epididymis weight and sperm concentration in the epididymis, and significantly increased the level of serum superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px). mRNA levels of autophagy related genes LC3 and Beclin1 decreased significantly with low dose TA compared to the control. However, compared to the control, high dose TA sharply reduced the levels of serum SOD, GSH-Px, CAT, serum testosterone (T), and mRNA level in steroidogenic acute regulatory protein (StAR) in the testis. Both sperm abnormality and mortality increased with high dose TA compared to the control and low dose TA. Collectively, this study demonstrated that TA treatment during puberty had a dose-dependent effect on the reproductive responses of male Brandt’s voles. TA might mediate autophagy in the testis, through both indirect and direct processes. TA mainly affected the reproductive function of male Brandt’s voles by regulating anti-oxidative levels. This study advances our understanding of the mechanisms by which tannins influence reproduction in herbivores. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702020000100319 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-46702020000100319 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.3897/zoologia.37.e52232 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Zoologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Zoologia |
dc.source.none.fl_str_mv |
Zoologia (Curitiba) v.37 2020 reponame:Zoologia (Curitiba. Online) instname:Sociedade Brasileira de Zoologia instacron:SBZ |
instname_str |
Sociedade Brasileira de Zoologia |
instacron_str |
SBZ |
institution |
SBZ |
reponame_str |
Zoologia (Curitiba. Online) |
collection |
Zoologia (Curitiba. Online) |
repository.name.fl_str_mv |
Zoologia (Curitiba. Online) - Sociedade Brasileira de Zoologia |
repository.mail.fl_str_mv |
sbz@sbzoologia.org.br |
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1750318092862357504 |