THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Tipo de documento: | preprint |
Idioma: | spa |
Título da fonte: | SciELO Preprints |
Texto Completo: | https://preprints.scielo.org/index.php/scielo/preprint/view/981 |
Resumo: | Coronavirus disease compromises all biological organs and systems, either by direct commitment to specific tissues or by indirect effects. The endocrine system is no exception, and parenchyma and thyroid function have been reported to be impaired. In 2003 a histopathological study on the effects of SARS-CoV infection on the thyroid showed extensive damage to parafollicular cells and destruction and exfoliation of epithelial cells in the thyroid follicle, an interesting finding was the absence of an inflammatory infiltrate. which supported the hypothesis of extensive apoptosis responsible for the findings. In China, minimally invasive autopsies of different organs of patients who died of SARS-CoV-2 did not report abnormalities in thyroid follicular morphology, but noted lymphocytic infiltration in the interstitium; none of the tissue immunohistochemistry and PCR analyzes detected SARS-CoV-2 in the thyroid. The first case of thyroid alteration compatible with subacute thyroiditis in a patient with COVID-19 in Peru is presented. |
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THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASEGLANDULA TIROIDES, ¿OTRA VICTIMA DEL COVID-19? A PROPOSITO DE UN CASOCOVID-19SARS-CoV-2coronavirussubacute thyroiditisPeruCOVID-19SARS-CoV-2coronavirustiroiditis subagudaPerúCoronavirus disease compromises all biological organs and systems, either by direct commitment to specific tissues or by indirect effects. The endocrine system is no exception, and parenchyma and thyroid function have been reported to be impaired. In 2003 a histopathological study on the effects of SARS-CoV infection on the thyroid showed extensive damage to parafollicular cells and destruction and exfoliation of epithelial cells in the thyroid follicle, an interesting finding was the absence of an inflammatory infiltrate. which supported the hypothesis of extensive apoptosis responsible for the findings. In China, minimally invasive autopsies of different organs of patients who died of SARS-CoV-2 did not report abnormalities in thyroid follicular morphology, but noted lymphocytic infiltration in the interstitium; none of the tissue immunohistochemistry and PCR analyzes detected SARS-CoV-2 in the thyroid. The first case of thyroid alteration compatible with subacute thyroiditis in a patient with COVID-19 in Peru is presented.La enfermedad por coronavirus compromete todos los órganos y sistemas biológicos, ya sea por compromiso directo a tejidos específicos o por efectos indirectos. El sistema endocrino no es una excepción y la función y parénquima tiroideos se han reportado alterados. En el 2003 un estudio histopatológico sobre los efectos de la infección por SARS-CoV en la tiroides mostró una lesión extensa de las células para-foliculares y la destrucción y exfoliación de las células epiteliales en el folículo tiroideo, un hallazgo interesante fue la ausencia de infiltrado inflamatorio lo que respaldó la hipótesis de una apoptosis extensa responsable de los hallazgos. En China, autopsias mínimamente invasivas de diferentes órganos de pacientes fallecidos por SARS-CoV-2 no informaron anormalidades en la morfología folicular tiroidea, pero notaron infiltración linfocítica en el intersticio; ninguno de los análisis de inmuno-histoquímica tisular y PCR detectó SARS-CoV-2 en la tiroides. Se presenta el primer caso de alteración tiroidea compatible con tiroiditis subaguda en una paciente con COVID-19 en Perú.SciELO PreprintsSciELO PreprintsSciELO Preprints2020-07-20info:eu-repo/semantics/preprintinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://preprints.scielo.org/index.php/scielo/preprint/view/98110.1590/SciELOPreprints.981spahttps://preprints.scielo.org/index.php/scielo/article/view/981/1391Copyright (c) 2020 Jose Paz-Ibarrahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessPaz-Ibarra, Josereponame:SciELO Preprintsinstname:SciELOinstacron:SCI2020-07-17T15:02:42Zoai:ops.preprints.scielo.org:preprint/981Servidor de preprintshttps://preprints.scielo.org/index.php/scieloONGhttps://preprints.scielo.org/index.php/scielo/oaiscielo.submission@scielo.orgopendoar:2020-07-17T15:02:42SciELO Preprints - SciELOfalse |
dc.title.none.fl_str_mv |
THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE GLANDULA TIROIDES, ¿OTRA VICTIMA DEL COVID-19? A PROPOSITO DE UN CASO |
title |
THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE |
spellingShingle |
THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE Paz-Ibarra, Jose COVID-19 SARS-CoV-2 coronavirus subacute thyroiditis Peru COVID-19 SARS-CoV-2 coronavirus tiroiditis subaguda Perú |
title_short |
THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE |
title_full |
THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE |
title_fullStr |
THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE |
title_full_unstemmed |
THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE |
title_sort |
THYROID GLAND, ANOTHER VICTIM OF COVID-19? ABOUT A CASE |
author |
Paz-Ibarra, Jose |
author_facet |
Paz-Ibarra, Jose |
author_role |
author |
dc.contributor.author.fl_str_mv |
Paz-Ibarra, Jose |
dc.subject.por.fl_str_mv |
COVID-19 SARS-CoV-2 coronavirus subacute thyroiditis Peru COVID-19 SARS-CoV-2 coronavirus tiroiditis subaguda Perú |
topic |
COVID-19 SARS-CoV-2 coronavirus subacute thyroiditis Peru COVID-19 SARS-CoV-2 coronavirus tiroiditis subaguda Perú |
description |
Coronavirus disease compromises all biological organs and systems, either by direct commitment to specific tissues or by indirect effects. The endocrine system is no exception, and parenchyma and thyroid function have been reported to be impaired. In 2003 a histopathological study on the effects of SARS-CoV infection on the thyroid showed extensive damage to parafollicular cells and destruction and exfoliation of epithelial cells in the thyroid follicle, an interesting finding was the absence of an inflammatory infiltrate. which supported the hypothesis of extensive apoptosis responsible for the findings. In China, minimally invasive autopsies of different organs of patients who died of SARS-CoV-2 did not report abnormalities in thyroid follicular morphology, but noted lymphocytic infiltration in the interstitium; none of the tissue immunohistochemistry and PCR analyzes detected SARS-CoV-2 in the thyroid. The first case of thyroid alteration compatible with subacute thyroiditis in a patient with COVID-19 in Peru is presented. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-07-20 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/preprint info:eu-repo/semantics/publishedVersion |
format |
preprint |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/preprint/view/981 10.1590/SciELOPreprints.981 |
url |
https://preprints.scielo.org/index.php/scielo/preprint/view/981 |
identifier_str_mv |
10.1590/SciELOPreprints.981 |
dc.language.iso.fl_str_mv |
spa |
language |
spa |
dc.relation.none.fl_str_mv |
https://preprints.scielo.org/index.php/scielo/article/view/981/1391 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2020 Jose Paz-Ibarra https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2020 Jose Paz-Ibarra https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
SciELO Preprints SciELO Preprints SciELO Preprints |
publisher.none.fl_str_mv |
SciELO Preprints SciELO Preprints SciELO Preprints |
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reponame:SciELO Preprints instname:SciELO instacron:SCI |
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SciELO |
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SCI |
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SCI |
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SciELO Preprints |
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SciELO Preprints |
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SciELO Preprints - SciELO |
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scielo.submission@scielo.org |
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1797047819405623296 |