CAN LOCAL ANESTHETICS HELP WITH THE HEALING PROCESS OF SURGICAL WOUNDS?

• Autor(a) principal: Carstens , Márcio Grande
• Data de Publicação: 2024
• Outros Autores: Marcondes Ribas Filho, Jurandir, Franck , Claudio Luciano, Czeczko , Nicolau Gregori, Sigwalt , Marcos Fabiano, Cuenca, Ronaldo Mafia, Andreollo, Nelson Adami, Manso , Jose Eduardo Ferreira, Tabushi, Fernando Issamu, Malafaia, Matheus Toniolo
• Tipo de documento: preprint
• Idioma: por
• Título da fonte: SciELO Preprints
• Texto Completo: https://preprints.scielo.org/index.php/scielo/preprint/view/7987
• topic: Anestésicos locais; Cicatrização; Neovascularização; Colágeno; Local anesthetics; Healing; Neovascularization; Collagen

Introduction: Evaluating the scarring differences between areas previously anesthetized with different local anesthetics is interesting to verify whether the choice of anesthetic helps in surgical healing in relation to inflammation, neovascularization and collagen deposition. Objectives: Review the existing literature with a focus on analyzing the role of local anesthetics in aiding the healing of surgical wounds. Method: Narrative review of literature selected from the SciELO – Scientific Electronic Library Online, Google Scholar, Pubmed and Scopus platforms. Initially, the review searched for keywords in the focus of the research, based on MESH/DeCS with the following terms: “local anesthetics, healing, neovascularization, collagen” with AND or OR search, considering the title and/or abstract. Next, only those that were most related to the topic were included, and the texts were read for inclusion. Results: 73 articles were included, read and interpreted focusing on the role of anesthetics in healing, pain, side effects and the best that currently emerge in analgesia and scar potential. Conclusions: No differences were observed between the anesthetics studied in terms of healing, inflammation and neovascularization. However, there was a significant difference in the production of collagens with an intensity of 6 to 12 times greater than collagen types I, II and III with the use of levobupivacaine.