Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000300011 |
Resumo: | The aim of the present study was to investigate the in vivo anti-metastatic activity of the red pigments of red yolk eggs laid by the ducks dieting on Potamogeton cripus L on the mammary carcinoma (4T1). The pigments were extracted with petroleum ether and acetone (2:1, v/v). BALB/c mice were divided into three groups (n=6), fed with the extracts at 150 mg/kg body weight (BW)/day (DEYE-H) or at 50 mg/kg BW/day (DEYE-L) and identical buffer without the extract (control group). The extracts were administered for 34 days. The treatment significantly inhibited the growth of orthotopical 4T1 tumour (DEYE-H vs control, 1:2; DEYE-L vs control, 2:3) and reduced the metastasis of tumour in the lungs (DEYE-H vs control, 4:7; DEYE-L vs control, 5:7), without statistical difference of body weight among the three groups. |
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Brazilian Archives of Biology and Technology |
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Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in miceduck egg yolkextractsmammary carcinomametastasis4T1 CellsBALB/c miceThe aim of the present study was to investigate the in vivo anti-metastatic activity of the red pigments of red yolk eggs laid by the ducks dieting on Potamogeton cripus L on the mammary carcinoma (4T1). The pigments were extracted with petroleum ether and acetone (2:1, v/v). BALB/c mice were divided into three groups (n=6), fed with the extracts at 150 mg/kg body weight (BW)/day (DEYE-H) or at 50 mg/kg BW/day (DEYE-L) and identical buffer without the extract (control group). The extracts were administered for 34 days. The treatment significantly inhibited the growth of orthotopical 4T1 tumour (DEYE-H vs control, 1:2; DEYE-L vs control, 2:3) and reduced the metastasis of tumour in the lungs (DEYE-H vs control, 4:7; DEYE-L vs control, 5:7), without statistical difference of body weight among the three groups.Instituto de Tecnologia do Paraná - Tecpar2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000300011Brazilian Archives of Biology and Technology v.54 n.3 2011reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132011000300011info:eu-repo/semantics/openAccessQi-bin,SongYi,YaoWei-guo,HuSheng-hua,ZhangXiao-wei,YanRui,Yangeng2011-06-13T00:00:00Zoai:scielo:S1516-89132011000300011Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2011-06-13T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice |
title |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice |
spellingShingle |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice Qi-bin,Song duck egg yolk extracts mammary carcinoma metastasis 4T1 Cells BALB/c mice |
title_short |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice |
title_full |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice |
title_fullStr |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice |
title_full_unstemmed |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice |
title_sort |
Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice |
author |
Qi-bin,Song |
author_facet |
Qi-bin,Song Yi,Yao Wei-guo,Hu Sheng-hua,Zhang Xiao-wei,Yan Rui,Yang |
author_role |
author |
author2 |
Yi,Yao Wei-guo,Hu Sheng-hua,Zhang Xiao-wei,Yan Rui,Yang |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Qi-bin,Song Yi,Yao Wei-guo,Hu Sheng-hua,Zhang Xiao-wei,Yan Rui,Yang |
dc.subject.por.fl_str_mv |
duck egg yolk extracts mammary carcinoma metastasis 4T1 Cells BALB/c mice |
topic |
duck egg yolk extracts mammary carcinoma metastasis 4T1 Cells BALB/c mice |
description |
The aim of the present study was to investigate the in vivo anti-metastatic activity of the red pigments of red yolk eggs laid by the ducks dieting on Potamogeton cripus L on the mammary carcinoma (4T1). The pigments were extracted with petroleum ether and acetone (2:1, v/v). BALB/c mice were divided into three groups (n=6), fed with the extracts at 150 mg/kg body weight (BW)/day (DEYE-H) or at 50 mg/kg BW/day (DEYE-L) and identical buffer without the extract (control group). The extracts were administered for 34 days. The treatment significantly inhibited the growth of orthotopical 4T1 tumour (DEYE-H vs control, 1:2; DEYE-L vs control, 2:3) and reduced the metastasis of tumour in the lungs (DEYE-H vs control, 4:7; DEYE-L vs control, 5:7), without statistical difference of body weight among the three groups. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000300011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000300011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-89132011000300011 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.54 n.3 2011 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318274497740800 |