Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Archives of Biology and Technology |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700032 |
Resumo: | 99mTc is a radionuclide widely used for imaging diagnosis in nuclear medicine. In Brazil it is obtained by elution from 99Mo-99mTc generators supplied by the Nuclear Energy Research Institute (IPEN). The elution is carried out in radiopharmacy laboratories located in hospitals and clinics. Depending of the quality of the generator and conditions of use during the elution process, 99Mo can be extracted from the column of the generator, becoming a radionuclidic impurity of the eluate used for the obtention of the radiopharmaceutical to be administered to the patient. 99Mo emits high-energy photons and beta particles and its presence degrades the quality of the image and unnecessarily increases the radiation dose delivered to the patient. An in-vivo measurement technique was developed to verify the occurrence of internal contamination by 99Mo in nuclear medicine patients. Direct measurements were made in a volunteer who underwent myocardial scintigraphy with 99mTc-sestamibi. The results indicated the presence of internal contamination of the patien by 99Mot. The activity was tracked for several days, and an assessment of the radiation dose from the contaminant 99Mo was made. |
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Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTcMolybdenum 99technetium 99mnuclear medicineinternal dosimetryin vivo measurementswhole body counter99mTc is a radionuclide widely used for imaging diagnosis in nuclear medicine. In Brazil it is obtained by elution from 99Mo-99mTc generators supplied by the Nuclear Energy Research Institute (IPEN). The elution is carried out in radiopharmacy laboratories located in hospitals and clinics. Depending of the quality of the generator and conditions of use during the elution process, 99Mo can be extracted from the column of the generator, becoming a radionuclidic impurity of the eluate used for the obtention of the radiopharmaceutical to be administered to the patient. 99Mo emits high-energy photons and beta particles and its presence degrades the quality of the image and unnecessarily increases the radiation dose delivered to the patient. An in-vivo measurement technique was developed to verify the occurrence of internal contamination by 99Mo in nuclear medicine patients. Direct measurements were made in a volunteer who underwent myocardial scintigraphy with 99mTc-sestamibi. The results indicated the presence of internal contamination of the patien by 99Mot. The activity was tracked for several days, and an assessment of the radiation dose from the contaminant 99Mo was made.Instituto de Tecnologia do Paraná - Tecpar2005-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700032Brazilian Archives of Biology and Technology v.48 n.spe2 2005reponame:Brazilian Archives of Biology and Technologyinstname:Instituto de Tecnologia do Paraná (Tecpar)instacron:TECPAR10.1590/S1516-89132005000700032info:eu-repo/semantics/openAccessDantas,Bernardo MaranhãoDantas,Ana Letícia AlmeidaMarques,Fábio Luiz NavarroBertelli,LuizStabin,Michael G.eng2005-12-09T00:00:00Zoai:scielo:S1516-89132005000700032Revistahttps://www.scielo.br/j/babt/https://old.scielo.br/oai/scielo-oai.phpbabt@tecpar.br||babt@tecpar.br1678-43241516-8913opendoar:2005-12-09T00:00Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar)false |
dc.title.none.fl_str_mv |
Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc |
title |
Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc |
spellingShingle |
Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc Dantas,Bernardo Maranhão Molybdenum 99 technetium 99m nuclear medicine internal dosimetry in vivo measurements whole body counter |
title_short |
Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc |
title_full |
Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc |
title_fullStr |
Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc |
title_full_unstemmed |
Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc |
title_sort |
Determination of 99Mo contamination in a nuclear medicine patient submitted to a diagnostic procedure with 99mTc |
author |
Dantas,Bernardo Maranhão |
author_facet |
Dantas,Bernardo Maranhão Dantas,Ana Letícia Almeida Marques,Fábio Luiz Navarro Bertelli,Luiz Stabin,Michael G. |
author_role |
author |
author2 |
Dantas,Ana Letícia Almeida Marques,Fábio Luiz Navarro Bertelli,Luiz Stabin,Michael G. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Dantas,Bernardo Maranhão Dantas,Ana Letícia Almeida Marques,Fábio Luiz Navarro Bertelli,Luiz Stabin,Michael G. |
dc.subject.por.fl_str_mv |
Molybdenum 99 technetium 99m nuclear medicine internal dosimetry in vivo measurements whole body counter |
topic |
Molybdenum 99 technetium 99m nuclear medicine internal dosimetry in vivo measurements whole body counter |
description |
99mTc is a radionuclide widely used for imaging diagnosis in nuclear medicine. In Brazil it is obtained by elution from 99Mo-99mTc generators supplied by the Nuclear Energy Research Institute (IPEN). The elution is carried out in radiopharmacy laboratories located in hospitals and clinics. Depending of the quality of the generator and conditions of use during the elution process, 99Mo can be extracted from the column of the generator, becoming a radionuclidic impurity of the eluate used for the obtention of the radiopharmaceutical to be administered to the patient. 99Mo emits high-energy photons and beta particles and its presence degrades the quality of the image and unnecessarily increases the radiation dose delivered to the patient. An in-vivo measurement technique was developed to verify the occurrence of internal contamination by 99Mo in nuclear medicine patients. Direct measurements were made in a volunteer who underwent myocardial scintigraphy with 99mTc-sestamibi. The results indicated the presence of internal contamination of the patien by 99Mot. The activity was tracked for several days, and an assessment of the radiation dose from the contaminant 99Mo was made. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700032 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132005000700032 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1516-89132005000700032 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
publisher.none.fl_str_mv |
Instituto de Tecnologia do Paraná - Tecpar |
dc.source.none.fl_str_mv |
Brazilian Archives of Biology and Technology v.48 n.spe2 2005 reponame:Brazilian Archives of Biology and Technology instname:Instituto de Tecnologia do Paraná (Tecpar) instacron:TECPAR |
instname_str |
Instituto de Tecnologia do Paraná (Tecpar) |
instacron_str |
TECPAR |
institution |
TECPAR |
reponame_str |
Brazilian Archives of Biology and Technology |
collection |
Brazilian Archives of Biology and Technology |
repository.name.fl_str_mv |
Brazilian Archives of Biology and Technology - Instituto de Tecnologia do Paraná (Tecpar) |
repository.mail.fl_str_mv |
babt@tecpar.br||babt@tecpar.br |
_version_ |
1750318270697701376 |