Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Tese |
Idioma: | por |
Título da fonte: | Biblioteca Digital de Teses e Dissertações da UCB |
Texto Completo: | https://bdtd.ucb.br:8443/jspui/handle/tede/2598 |
Resumo: | The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1?? Ten hypertensive elderly (??? = 7), 73.2 ?? 2.2 years, 13.2 ?? 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ?? 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ?? 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2?? Thirty-three elderly (??? = 15), 75.6 ?? 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ??Trolox/TBARS and ??lactate in relation to ??SBP (p < 0.05). ??TBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The ?? increase in absolute handgrip strength was associated with the reduction of ??SBP, ??DBP, ??HR and with increase in ??Trolox/TBARS and ??NO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved. |
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Biblioteca Digital de Teses e Dissertações da UCB |
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Moraes, Milton Rocha dehttp://lattes.cnpq.br/1690322593621016http://lattes.cnpq.br/7231951956450623Souza, Luiz Humberto Rodrigues2019-06-04T12:43:10Z2019-02-26SOUZA, Luiz Humberto Rodrigues. Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados. 2019. 139 f. Tese (Programa Stricto Sensu em Educa????o F??sica) - Universidade Cat??lica de Bras??lia, Bras??lia, 2019.https://bdtd.ucb.br:8443/jspui/handle/tede/2598The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1?? Ten hypertensive elderly (??? = 7), 73.2 ?? 2.2 years, 13.2 ?? 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ?? 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ?? 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2?? Thirty-three elderly (??? = 15), 75.6 ?? 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ??Trolox/TBARS and ??lactate in relation to ??SBP (p < 0.05). ??TBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The ?? increase in absolute handgrip strength was associated with the reduction of ??SBP, ??DBP, ??HR and with increase in ??Trolox/TBARS and ??NO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved.O objetivo deste estudo foi verificar o efeito agudo e cr??nico do exerc??cio isom??trico de preens??o manual (EIPM) sobre as vari??veis hemodin??micas e bioqu??micas em idosos pr??-hipertensos e hipertensos. Foram realizados dois estudos: 1?? Dez idosos hipertensos (??? = 7), 73,2 ?? 2,2 anos, 13,2 ?? 3,1 anos de hipertens??o, press??o arterial sist??lica (PAS) 135,1 ?? 6,5 mm Hg e press??o arterial diast??lica (PAD) 76,6 ?? 3,4 mm Hg foram submetidos a duas sess??es agudas, uma controle a 3% e outra a 30% da contra????o volunt??ria isom??trica m??xima (CVIM) utilizando um dinam??metro de preens??o manual hidr??ulico (Jamar, IL, USA). Os participantes completaram oito s??ries de um minuto de contra????o isom??trica, bilateralmente, com pausa de um minuto. A press??o arterial (PA) e a frequ??ncia card??aca (FC) foram mensuradas em repouso e 1, 5, 10, 15, 30, 45 e 60- min p??s-exerc??cio. O lactato sangu??neo e o ??xido n??trico (NO-) salivar foram coletados em repouso, 0, 30 e 60- min p??s-exerc??cio. 2?? Trinta e tr??s idosos (??? = 15), 75,6 ?? 1,2 anos, foram divididos em 3 grupos: controle hipertenso (GC, n = 11), pr??-hipertenso (GPH, n = 10) e hipertenso (GH, n = 12). O treinamento isom??trico de preens??o manual (TIPM) foi realizado durante 8 semanas, 3 vezes por semana em dias n??o consecutivos. A intensidade e o volume do TIPM foram os mesmos do estudo 1. Houve um per??odo sem exerc??cio ap??s o TIPM de 4 semanas. As vari??veis antropom??tricas e bioqu??micas foram avaliadas pr?? e p??s- TIPM. As vari??veis hemodin??micas e neuromusculares foram mensuradas antes, durante e ap??s o TIPM. No estudo 1 houve uma redu????o da PAS ap??s a sess??o de 30% CVIM a partir do 10?? min p??s-exerc??cio (p < 0,05). Aos 60 minutos p??sexerc??cio, a PAS foi menor na sess??o 30% vs. 3% CVIM (p = 0,006). N??o houve diferen??a para as demais vari??veis (p > 0,05). No estudo 2, o TIPM reduziu a PAS e a FC em ambos os grupos treinados (GPH e GH). A PAD e a PA m??dia diminu??ram apenas no GH (p < 0,05). As redu????es dos n??veis press??ricos induzidas pelo TIPM foram mantidas durante o per??odo sem o EIPM. Verificou-se uma associa????o inversa do ??Trolox/TBARS e ??lactato em rela????o ao ??PAS (p < 0,05). O ??TBARS apresentou associa????o positiva com as redu????es da PAD e da FC ap??s o TIPM (p < 0,05). O TIPM induziu aumento nas concentra????es do NO- plasm??tico (p < 0,05). O ?? de aumento na for??a de preens??o manual absoluta foi associado com a redu????o do ??PAS, ??PAD, ??FC e com o aumento no ??Trolox/TBARS e ??NO- ap??s o TIPM (p < 0,05). Concluindo, o estudo 1 demonstrou que o EIPM induziu uma hipotens??o p??s-exerc??cio isom??trico em idosos hipertensos, sem associa????o com as concentra????es de lactato e NO-. No estudo 2, o TIPM tamb??m induziu uma redu????o dos n??veis press??ricos e da FC em idosos pr??-hipertensos e hipertensos. vasodilata????o mediada pelo fluxo dependente do endot??lio e a melhora no estado redox podem ser os poss??veis mecanismos envolvidos.Submitted by Sara Ribeiro (sara.ribeiro@ucb.br) on 2019-06-04T12:43:02Z No. of bitstreams: 1 LuizHumbertoRodriguesSouzaTese2019.pdf: 6040274 bytes, checksum: a438379b8bffad1cbd723172d289b555 (MD5)Approved for entry into archive by Sara Ribeiro (sara.ribeiro@ucb.br) on 2019-06-04T12:43:10Z (GMT) No. of bitstreams: 1 LuizHumbertoRodriguesSouzaTese2019.pdf: 6040274 bytes, checksum: a438379b8bffad1cbd723172d289b555 (MD5)Made available in DSpace on 2019-06-04T12:43:10Z (GMT). No. of bitstreams: 1 LuizHumbertoRodriguesSouzaTese2019.pdf: 6040274 bytes, checksum: a438379b8bffad1cbd723172d289b555 (MD5) Previous issue date: 2019-02-26application/pdfhttps://bdtd.ucb.br:8443/jspui/retrieve/6486/LuizHumbertoRodriguesSouzaTese2019.pdf.jpgporUniversidade Cat??lica de Bras??liaPrograma Stricto Sensu em Educa????o F??sicaUCBBrasilEscola de Sa??de e MedicinaHipertens??oHemodin??micaEnvelhecimentoPreens??o manualEstresse oxidativoOxidative stressHemodynamicHypertensionHandgripAgingCNPQ::CIENCIAS DA SAUDE::EDUCACAO FISICAEfeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizadosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UCBinstname:Universidade Católica de Brasília (UCB)instacron:UCBLICENSElicense.txtlicense.txttext/plain; charset=utf-81831https://200.214.135.178:8443/jspui/bitstream/tede/2598/1/license.txtd7d5e5ec75089f122abe937645a56120MD51ORIGINALLuizHumbertoRodriguesSouzaTese2019.pdfLuizHumbertoRodriguesSouzaTese2019.pdfapplication/pdf6040274https://200.214.135.178:8443/jspui/bitstream/tede/2598/2/LuizHumbertoRodriguesSouzaTese2019.pdfa438379b8bffad1cbd723172d289b555MD52TEXTLuizHumbertoRodriguesSouzaTese2019.pdf.txtLuizHumbertoRodriguesSouzaTese2019.pdf.txttext/plain219834https://200.214.135.178:8443/jspui/bitstream/tede/2598/3/LuizHumbertoRodriguesSouzaTese2019.pdf.txteaede97a47eaac1d05dc3120cf406b33MD53THUMBNAILLuizHumbertoRodriguesSouzaTese2019.pdf.jpgLuizHumbertoRodriguesSouzaTese2019.pdf.jpgimage/jpeg6059https://200.214.135.178:8443/jspui/bitstream/tede/2598/4/LuizHumbertoRodriguesSouzaTese2019.pdf.jpg16d704d1e0fcd47accbc44bcece934ceMD54tede/25982019-06-05 01:05:38.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Biblioteca Digital de Teses e Dissertaçõeshttps://bdtd.ucb.br:8443/jspui/ |
dc.title.por.fl_str_mv |
Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados |
title |
Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados |
spellingShingle |
Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados Souza, Luiz Humberto Rodrigues Hipertens??o Hemodin??mica Envelhecimento Preens??o manual Estresse oxidativo Oxidative stress Hemodynamic Hypertension Handgrip Aging CNPQ::CIENCIAS DA SAUDE::EDUCACAO FISICA |
title_short |
Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados |
title_full |
Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados |
title_fullStr |
Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados |
title_full_unstemmed |
Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados |
title_sort |
Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados |
author |
Souza, Luiz Humberto Rodrigues |
author_facet |
Souza, Luiz Humberto Rodrigues |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Moraes, Milton Rocha de |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/1690322593621016 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/7231951956450623 |
dc.contributor.author.fl_str_mv |
Souza, Luiz Humberto Rodrigues |
contributor_str_mv |
Moraes, Milton Rocha de |
dc.subject.por.fl_str_mv |
Hipertens??o Hemodin??mica Envelhecimento Preens??o manual Estresse oxidativo |
topic |
Hipertens??o Hemodin??mica Envelhecimento Preens??o manual Estresse oxidativo Oxidative stress Hemodynamic Hypertension Handgrip Aging CNPQ::CIENCIAS DA SAUDE::EDUCACAO FISICA |
dc.subject.eng.fl_str_mv |
Oxidative stress Hemodynamic Hypertension Handgrip Aging |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS DA SAUDE::EDUCACAO FISICA |
dc.description.abstract.eng.fl_txt_mv |
The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1?? Ten hypertensive elderly (??? = 7), 73.2 ?? 2.2 years, 13.2 ?? 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ?? 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ?? 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2?? Thirty-three elderly (??? = 15), 75.6 ?? 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ??Trolox/TBARS and ??lactate in relation to ??SBP (p < 0.05). ??TBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The ?? increase in absolute handgrip strength was associated with the reduction of ??SBP, ??DBP, ??HR and with increase in ??Trolox/TBARS and ??NO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved. |
dc.description.abstract.por.fl_txt_mv |
O objetivo deste estudo foi verificar o efeito agudo e cr??nico do exerc??cio isom??trico de preens??o manual (EIPM) sobre as vari??veis hemodin??micas e bioqu??micas em idosos pr??-hipertensos e hipertensos. Foram realizados dois estudos: 1?? Dez idosos hipertensos (??? = 7), 73,2 ?? 2,2 anos, 13,2 ?? 3,1 anos de hipertens??o, press??o arterial sist??lica (PAS) 135,1 ?? 6,5 mm Hg e press??o arterial diast??lica (PAD) 76,6 ?? 3,4 mm Hg foram submetidos a duas sess??es agudas, uma controle a 3% e outra a 30% da contra????o volunt??ria isom??trica m??xima (CVIM) utilizando um dinam??metro de preens??o manual hidr??ulico (Jamar, IL, USA). Os participantes completaram oito s??ries de um minuto de contra????o isom??trica, bilateralmente, com pausa de um minuto. A press??o arterial (PA) e a frequ??ncia card??aca (FC) foram mensuradas em repouso e 1, 5, 10, 15, 30, 45 e 60- min p??s-exerc??cio. O lactato sangu??neo e o ??xido n??trico (NO-) salivar foram coletados em repouso, 0, 30 e 60- min p??s-exerc??cio. 2?? Trinta e tr??s idosos (??? = 15), 75,6 ?? 1,2 anos, foram divididos em 3 grupos: controle hipertenso (GC, n = 11), pr??-hipertenso (GPH, n = 10) e hipertenso (GH, n = 12). O treinamento isom??trico de preens??o manual (TIPM) foi realizado durante 8 semanas, 3 vezes por semana em dias n??o consecutivos. A intensidade e o volume do TIPM foram os mesmos do estudo 1. Houve um per??odo sem exerc??cio ap??s o TIPM de 4 semanas. As vari??veis antropom??tricas e bioqu??micas foram avaliadas pr?? e p??s- TIPM. As vari??veis hemodin??micas e neuromusculares foram mensuradas antes, durante e ap??s o TIPM. No estudo 1 houve uma redu????o da PAS ap??s a sess??o de 30% CVIM a partir do 10?? min p??s-exerc??cio (p < 0,05). Aos 60 minutos p??sexerc??cio, a PAS foi menor na sess??o 30% vs. 3% CVIM (p = 0,006). N??o houve diferen??a para as demais vari??veis (p > 0,05). No estudo 2, o TIPM reduziu a PAS e a FC em ambos os grupos treinados (GPH e GH). A PAD e a PA m??dia diminu??ram apenas no GH (p < 0,05). As redu????es dos n??veis press??ricos induzidas pelo TIPM foram mantidas durante o per??odo sem o EIPM. Verificou-se uma associa????o inversa do ??Trolox/TBARS e ??lactato em rela????o ao ??PAS (p < 0,05). O ??TBARS apresentou associa????o positiva com as redu????es da PAD e da FC ap??s o TIPM (p < 0,05). O TIPM induziu aumento nas concentra????es do NO- plasm??tico (p < 0,05). O ?? de aumento na for??a de preens??o manual absoluta foi associado com a redu????o do ??PAS, ??PAD, ??FC e com o aumento no ??Trolox/TBARS e ??NO- ap??s o TIPM (p < 0,05). Concluindo, o estudo 1 demonstrou que o EIPM induziu uma hipotens??o p??s-exerc??cio isom??trico em idosos hipertensos, sem associa????o com as concentra????es de lactato e NO-. No estudo 2, o TIPM tamb??m induziu uma redu????o dos n??veis press??ricos e da FC em idosos pr??-hipertensos e hipertensos. vasodilata????o mediada pelo fluxo dependente do endot??lio e a melhora no estado redox podem ser os poss??veis mecanismos envolvidos. |
description |
The objective of this study was to verify the acute and chronic effect of isometric handgrip (IHG) exercise on the hemodynamic and biochemical variables in the prehypertensive and hypertensive elderly subjects. Two studies were performed: 1?? Ten hypertensive elderly (??? = 7), 73.2 ?? 2.2 years, 13.2 ?? 3.1 years of hypertension, systolic blood pressure (SBP) 135.1 ?? 6.5 mm Hg and diastolic blood pressure (DBP) of 76.6 ?? 3.4 mm Hg were submitted to two acute sessions, a 3% control and another to 30% of maximal isometric voluntary contraction (MIVC) using a handgrip hydraulic dynamometer (Jamar, IL, USA). Participants completed eight sets of one minute isometric contraction, bilaterally, with one-minute pause. Blood pressure (BP) and heart rate (HR) were measured at rest and at 1, 5, 10, 15, 30, 45 and 60 min postexercise. Blood lactate and salivary nitric oxide (NO-) were collected at rest, 0, 30 and 60 min after exercise. 2?? Thirty-three elderly (??? = 15), 75.6 ?? 1.2 years, were divided into three groups: hypertensive control (CG, n = 11), prehypertensive (PHG, n = 10) and hypertensive (HG = 12). Isometric handgrip training (IHT) was performed for 8 weeks, 3 times a week on non-consecutive days. The intensity and volume of the IHT were the same as in study 1. There was a non-exercise period after the 4- week IHT. Anthropometric and biochemical variables were evaluated before and after IHT. Hemodynamic and neuromuscular variables were measured before, during and after IHT. In study 1 there was a reduction of SBP after the session of 30% MVIC from the 10th min post-exercise (p < 0.05). At 60 minutes post-exercise, SBP was lower in the 30% vs. 3% MVIC (p = 0.006). There was no difference for the other variables (p > 0.05). In study 2, IHT reduced SBP and HR in both trained groups (PHG and HG). DBP and mean BP decreased only in HG (p < 0.05). Reductions in pressure levels induced by IHT were maintained during the period without IHG exercise. There was an inverse association of ??Trolox/TBARS and ??lactate in relation to ??SBP (p < 0.05). ??TBARS was positively associated with reductions in DBP and HR after IHT (p < 0.05). IHT induced increase in NO- concentrations (p < 0.05). The ?? increase in absolute handgrip strength was associated with the reduction of ??SBP, ??DBP, ??HR and with increase in ??Trolox/TBARS and ??NO- after IHT (p < 0.05). In conclusion, study 1 demonstrated that IHG exercise induced postisometric exercise hypotension in hypertensive elderly, with no association with lactate and NO- concentrations. In study 2, IHT also induced a reduction in BP and HR levels in prehypertensive and hypertensive elderly subjects. Endotheliumdependent flow mediated vasodilation and improvement in the redox state may be the possible mechanisms involved. |
publishDate |
2019 |
dc.date.accessioned.fl_str_mv |
2019-06-04T12:43:10Z |
dc.date.issued.fl_str_mv |
2019-02-26 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
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publishedVersion |
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doctoralThesis |
dc.identifier.citation.fl_str_mv |
SOUZA, Luiz Humberto Rodrigues. Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados. 2019. 139 f. Tese (Programa Stricto Sensu em Educa????o F??sica) - Universidade Cat??lica de Bras??lia, Bras??lia, 2019. |
dc.identifier.uri.fl_str_mv |
https://bdtd.ucb.br:8443/jspui/handle/tede/2598 |
identifier_str_mv |
SOUZA, Luiz Humberto Rodrigues. Efeitos agudos e cr??nicos do exerc??cio isom??trico de preens??o manual nas vari??veis hemodin??micas, neuromusculares e bioqu??micas em idosos institucionalizados. 2019. 139 f. Tese (Programa Stricto Sensu em Educa????o F??sica) - Universidade Cat??lica de Bras??lia, Bras??lia, 2019. |
url |
https://bdtd.ucb.br:8443/jspui/handle/tede/2598 |
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por |
language |
por |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Universidade Cat??lica de Bras??lia |
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Programa Stricto Sensu em Educa????o F??sica |
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UCB |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Escola de Sa??de e Medicina |
publisher.none.fl_str_mv |
Universidade Cat??lica de Bras??lia |
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