Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Acta Scientiarum. Animal Sciences (Online) |
Texto Completo: | https://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/57927 |
Resumo: | . Litter size is one of the crucial factors in livestock production and is of high economic value, which is affected by ovulation rate, hormones, and growth factors. Growth factors play a multifaceted role in reproductive physiology. This review aims to investigate the association of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) with litter size in livestock. The transforming growth factor β (TGF- β) superfamily includes more than 34 members; GDF9 and BMP15 are among the most significant factors for regulating fertility and litter size in most livestock species. Ovarian follicles release BMP15 and GDF9 that are involved in the maturation of primary follicles into the basal form, proliferation of granulosa and theca cells, steroidogenesis, ovulation, and formation of the corpus luteum. Besides, these factors are highly expressed in oocytes and are necessary for female fertility and multiple ovulation in several livestock species. Animals with two inactive copies of these factors are sterile, while those with one inactive copy are fertile. Thus, the present review provides valuable information on the association of BMP15 and GDF9 with litter size in livestock that can be used as biological markers of multiple ovulation or for improving fertility in livestock. |
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Acta Scientiarum. Animal Sciences (Online) |
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Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study birth type; domestic animals; ovarian follicle; reproductive performance; TGF-β.birth type; domestic animals; ovarian follicle; reproductive performance; TGF-β.. Litter size is one of the crucial factors in livestock production and is of high economic value, which is affected by ovulation rate, hormones, and growth factors. Growth factors play a multifaceted role in reproductive physiology. This review aims to investigate the association of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) with litter size in livestock. The transforming growth factor β (TGF- β) superfamily includes more than 34 members; GDF9 and BMP15 are among the most significant factors for regulating fertility and litter size in most livestock species. Ovarian follicles release BMP15 and GDF9 that are involved in the maturation of primary follicles into the basal form, proliferation of granulosa and theca cells, steroidogenesis, ovulation, and formation of the corpus luteum. Besides, these factors are highly expressed in oocytes and are necessary for female fertility and multiple ovulation in several livestock species. Animals with two inactive copies of these factors are sterile, while those with one inactive copy are fertile. Thus, the present review provides valuable information on the association of BMP15 and GDF9 with litter size in livestock that can be used as biological markers of multiple ovulation or for improving fertility in livestock.. Litter size is one of the crucial factors in livestock production and is of high economic value, which is affected by ovulation rate, hormones, and growth factors. Growth factors play a multifaceted role in reproductive physiology. This review aims to investigate the association of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) with litter size in livestock. The transforming growth factor β (TGF- β) superfamily includes more than 34 members; GDF9 and BMP15 are among the most significant factors for regulating fertility and litter size in most livestock species. Ovarian follicles release BMP15 and GDF9 that are involved in the maturation of primary follicles into the basal form, proliferation of granulosa and theca cells, steroidogenesis, ovulation, and formation of the corpus luteum. Besides, these factors are highly expressed in oocytes and are necessary for female fertility and multiple ovulation in several livestock species. Animals with two inactive copies of these factors are sterile, while those with one inactive copy are fertile. Thus, the present review provides valuable information on the association of BMP15 and GDF9 with litter size in livestock that can be used as biological markers of multiple ovulation or for improving fertility in livestock.Editora da Universidade Estadual de Maringá2022-12-08info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/5792710.4025/actascianimsci.v45i1.57927Acta Scientiarum. Animal Sciences; Vol 45 (2023): Publicação contínua; e57927Acta Scientiarum. Animal Sciences; v. 45 (2023): Publicação contínua; e579271807-86721806-2636reponame:Acta Scientiarum. Animal Sciences (Online)instname:Universidade Estadual de Maringá (UEM)instacron:UEMenghttps://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/57927/751375155114Copyright (c) 2023 Acta Scientiarum. Animal Scienceshttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess Ajafar, Majeed Hameed Kadhim, Alaa Hasan Al-Thuwaini, Tahreer Mohammed Al-Shuhaib, Mohammed Baqur Sahib Hussein, Tamadhur Hani 2023-02-15T16:52:39Zoai:periodicos.uem.br/ojs:article/57927Revistahttp://www.periodicos.uem.br/ojs/index.php/ActaSciAnimSciPUBhttp://www.periodicos.uem.br/ojs/index.php/ActaSciAnimSci/oaiactaanim@uem.br||actaanim@uem.br|| rev.acta@gmail.com1807-86721806-2636opendoar:2023-02-15T16:52:39Acta Scientiarum. Animal Sciences (Online) - Universidade Estadual de Maringá (UEM)false |
dc.title.none.fl_str_mv |
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study |
title |
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study |
spellingShingle |
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study Ajafar, Majeed Hameed birth type; domestic animals; ovarian follicle; reproductive performance; TGF-β. birth type; domestic animals; ovarian follicle; reproductive performance; TGF-β. |
title_short |
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study |
title_full |
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study |
title_fullStr |
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study |
title_full_unstemmed |
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study |
title_sort |
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study |
author |
Ajafar, Majeed Hameed |
author_facet |
Ajafar, Majeed Hameed Kadhim, Alaa Hasan Al-Thuwaini, Tahreer Mohammed Al-Shuhaib, Mohammed Baqur Sahib Hussein, Tamadhur Hani |
author_role |
author |
author2 |
Kadhim, Alaa Hasan Al-Thuwaini, Tahreer Mohammed Al-Shuhaib, Mohammed Baqur Sahib Hussein, Tamadhur Hani |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Ajafar, Majeed Hameed Kadhim, Alaa Hasan Al-Thuwaini, Tahreer Mohammed Al-Shuhaib, Mohammed Baqur Sahib Hussein, Tamadhur Hani |
dc.subject.por.fl_str_mv |
birth type; domestic animals; ovarian follicle; reproductive performance; TGF-β. birth type; domestic animals; ovarian follicle; reproductive performance; TGF-β. |
topic |
birth type; domestic animals; ovarian follicle; reproductive performance; TGF-β. birth type; domestic animals; ovarian follicle; reproductive performance; TGF-β. |
description |
. Litter size is one of the crucial factors in livestock production and is of high economic value, which is affected by ovulation rate, hormones, and growth factors. Growth factors play a multifaceted role in reproductive physiology. This review aims to investigate the association of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) with litter size in livestock. The transforming growth factor β (TGF- β) superfamily includes more than 34 members; GDF9 and BMP15 are among the most significant factors for regulating fertility and litter size in most livestock species. Ovarian follicles release BMP15 and GDF9 that are involved in the maturation of primary follicles into the basal form, proliferation of granulosa and theca cells, steroidogenesis, ovulation, and formation of the corpus luteum. Besides, these factors are highly expressed in oocytes and are necessary for female fertility and multiple ovulation in several livestock species. Animals with two inactive copies of these factors are sterile, while those with one inactive copy are fertile. Thus, the present review provides valuable information on the association of BMP15 and GDF9 with litter size in livestock that can be used as biological markers of multiple ovulation or for improving fertility in livestock. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12-08 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/57927 10.4025/actascianimsci.v45i1.57927 |
url |
https://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/57927 |
identifier_str_mv |
10.4025/actascianimsci.v45i1.57927 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://periodicos.uem.br/ojs/index.php/ActaSciAnimSci/article/view/57927/751375155114 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Acta Scientiarum. Animal Sciences http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Acta Scientiarum. Animal Sciences http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Editora da Universidade Estadual de Maringá |
publisher.none.fl_str_mv |
Editora da Universidade Estadual de Maringá |
dc.source.none.fl_str_mv |
Acta Scientiarum. Animal Sciences; Vol 45 (2023): Publicação contínua; e57927 Acta Scientiarum. Animal Sciences; v. 45 (2023): Publicação contínua; e57927 1807-8672 1806-2636 reponame:Acta Scientiarum. Animal Sciences (Online) instname:Universidade Estadual de Maringá (UEM) instacron:UEM |
instname_str |
Universidade Estadual de Maringá (UEM) |
instacron_str |
UEM |
institution |
UEM |
reponame_str |
Acta Scientiarum. Animal Sciences (Online) |
collection |
Acta Scientiarum. Animal Sciences (Online) |
repository.name.fl_str_mv |
Acta Scientiarum. Animal Sciences (Online) - Universidade Estadual de Maringá (UEM) |
repository.mail.fl_str_mv |
actaanim@uem.br||actaanim@uem.br|| rev.acta@gmail.com |
_version_ |
1799315364170956800 |