First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil

Detalhes bibliográficos
Autor(a) principal: Silva, Aída Cristina do Nascimento
Data de Publicação: 2011
Outros Autores: Ferrazoli, Lucilaine, Simonsen, Vera, Reis, Joice Neves, Pereira, Susan Martins, Carmo, Theomira Mauadie Azevedo, Mota, Eduardo Luiz Andrade, Reis, Mitermayer Galvão
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5254
Resumo: This study constitutes a first attempt to describe the genetic population structure of Mycobacterium tuberculosis circulating in Salvador, Bahia State, Brazil. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June 2008, were analyzed using restriction fragment length polymorphism (IS6110-RFLP). The study population was characterized by a predominance of males (71.43%) over 30 years of age (68.75%). Forty-one isolates were found to belong to a single pattern (73.2%), while 15 (26.7%) were found in group patterns, forming six clusters. The higher level of diversity observed is much more suggestive of endogenous reactivation than recent transmission.
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spelling Silva, Aída Cristina do NascimentoFerrazoli, LucilaineSimonsen, VeraReis, Joice NevesPereira, Susan MartinsCarmo, Theomira Mauadie AzevedoMota, Eduardo Luiz AndradeReis, Mitermayer GalvãoSilva, Aída Cristina do NascimentoFerrazoli, LucilaineSimonsen, VeraReis, Joice NevesPereira, Susan MartinsCarmo, Theomira Mauadie AzevedoMota, Eduardo Luiz AndradeReis, Mitermayer Galvão2012-01-26T12:21:48Z2012-01-26T12:21:48Z20110102-311Xhttp://www.repositorio.ufba.br/ri/handle/ri/5254v.27, n.9, p.1859-1863, set, 2011.This study constitutes a first attempt to describe the genetic population structure of Mycobacterium tuberculosis circulating in Salvador, Bahia State, Brazil. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June 2008, were analyzed using restriction fragment length polymorphism (IS6110-RFLP). The study population was characterized by a predominance of males (71.43%) over 30 years of age (68.75%). Forty-one isolates were found to belong to a single pattern (73.2%), while 15 (26.7%) were found in group patterns, forming six clusters. The higher level of diversity observed is much more suggestive of endogenous reactivation than recent transmission.Submitted by Maria Creuza Silva (mariakreuza@yahoo.com.br) on 2012-01-26T12:21:48Z No. of bitstreams: 1 EMota 2011. Repositorio.pdf: 202435 bytes, checksum: 009495b8dcb57aeebecc6e1141216837 (MD5)Made available in DSpace on 2012-01-26T12:21:48Z (GMT). No. of bitstreams: 1 EMota 2011. 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dc.title.pt_BR.fl_str_mv First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil
dc.title.alternative.pt_BR.fl_str_mv Cad. Saúde Pública
title First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil
spellingShingle First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil
Silva, Aída Cristina do Nascimento
Tuberculosis
Molecular Epidemiology
Genetic Variation
Mycobacterium tuberculosis
title_short First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil
title_full First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil
title_fullStr First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil
title_full_unstemmed First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil
title_sort First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil
author Silva, Aída Cristina do Nascimento
author_facet Silva, Aída Cristina do Nascimento
Ferrazoli, Lucilaine
Simonsen, Vera
Reis, Joice Neves
Pereira, Susan Martins
Carmo, Theomira Mauadie Azevedo
Mota, Eduardo Luiz Andrade
Reis, Mitermayer Galvão
author_role author
author2 Ferrazoli, Lucilaine
Simonsen, Vera
Reis, Joice Neves
Pereira, Susan Martins
Carmo, Theomira Mauadie Azevedo
Mota, Eduardo Luiz Andrade
Reis, Mitermayer Galvão
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Silva, Aída Cristina do Nascimento
Ferrazoli, Lucilaine
Simonsen, Vera
Reis, Joice Neves
Pereira, Susan Martins
Carmo, Theomira Mauadie Azevedo
Mota, Eduardo Luiz Andrade
Reis, Mitermayer Galvão
Silva, Aída Cristina do Nascimento
Ferrazoli, Lucilaine
Simonsen, Vera
Reis, Joice Neves
Pereira, Susan Martins
Carmo, Theomira Mauadie Azevedo
Mota, Eduardo Luiz Andrade
Reis, Mitermayer Galvão
dc.subject.por.fl_str_mv Tuberculosis
Molecular Epidemiology
Genetic Variation
Mycobacterium tuberculosis
topic Tuberculosis
Molecular Epidemiology
Genetic Variation
Mycobacterium tuberculosis
description This study constitutes a first attempt to describe the genetic population structure of Mycobacterium tuberculosis circulating in Salvador, Bahia State, Brazil. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June 2008, were analyzed using restriction fragment length polymorphism (IS6110-RFLP). The study population was characterized by a predominance of males (71.43%) over 30 years of age (68.75%). Forty-one isolates were found to belong to a single pattern (73.2%), while 15 (26.7%) were found in group patterns, forming six clusters. The higher level of diversity observed is much more suggestive of endogenous reactivation than recent transmission.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2012-01-26T12:21:48Z
dc.date.available.fl_str_mv 2012-01-26T12:21:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5254
dc.identifier.issn.none.fl_str_mv 0102-311X
dc.identifier.number.pt_BR.fl_str_mv v.27, n.9, p.1859-1863, set, 2011.
identifier_str_mv 0102-311X
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