Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?

Detalhes bibliográficos
Autor(a) principal: Paraná, Raymundo
Data de Publicação: 2003
Outros Autores: Codes, Liana, Andrade, Zilton de Araújo, Freitas, Luiz A. R. de, Jesus, Rogério Santos, Reis, Mitermayer Galvão dos, Cotrim, Helma Pinchemel, Cunha, Simone, Trepo, Christian
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5043
Resumo: p.222—230
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spelling Paraná, RaymundoCodes, LianaAndrade, Zilton de AraújoFreitas, Luiz A. R. deJesus, Rogério SantosReis, Mitermayer Galvão dosCotrim, Helma PinchemelCunha, SimoneTrepo, ChristianParaná, RaymundoCodes, LianaAndrade, Zilton de AraújoFreitas, Luiz A. R. deJesus, Rogério SantosReis, Mitermayer Galvão dosCotrim, Helma PinchemelCunha, SimoneTrepo, Christian2012-01-06T12:04:01Z2012-01-06T12:04:01Z20031201-9712http://www.repositorio.ufba.br/ri/handle/ri/5043v. 7. n, 3.p.222—230Non-A E hepatitis and acute cryptogenic hepatitis are thc names given to the disease of patients with clinical hepatitis, but in whom serologic evidence of A—E hepatitis has not been found. Over a period of 8 years, we evaluated in ]3razil 32 patients who fuffilled the criteria for this diagnosis in order to determine patterns of the clinical illness, laboratory parameters, or histologic features. Each patient was subjected to virologic tests to exclude A—E hepatitis and cytomegalovirus/Epstein—Barr virus infection. Drug-induced hepatitis and autoimmune disease were also excluded. Wilson’s disease was excluded in young patients. lhe course of the disease was clinical/biochemical recovery in 3 months in 25 patients and persistent alanine aminotransferase (ALT) elevation in 7 patients. Three of these had chronic hepatitis, and one had severe fibrosis on liver biopsy. During the adute illness, mean peak ALT was 1267 IU/L, bilirubin was 4.0 mg/dL, and ferritin was 1393 IU/mL. GB virus type C (GBV—C) was found in six patients, and TI virus (TTV) in five patients. We conclude that, in Brazil, non-A—E hepatitis probably originates from still unidentified viruses. lhe course of the disease and the histologic patterns are similar to those recorded for known viruses. Continiious survey for the specific etiologic agents is needed.Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-01-06T12:04:01Z No. of bitstreams: 1 PIIS1201971203900567.pdf: 7348682 bytes, checksum: 1bbf60958c3341eb500e3ec1b1a62f1d (MD5)Made available in DSpace on 2012-01-06T12:04:01Z (GMT). No. of bitstreams: 1 PIIS1201971203900567.pdf: 7348682 bytes, checksum: 1bbf60958c3341eb500e3ec1b1a62f1d (MD5) Previous issue date: 2003Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?International Journal of Infectious Diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINALPIIS1201971203900567.pdfPIIS1201971203900567.pdfapplication/pdf7348682https://repositorio.ufba.br/bitstream/ri/5043/1/PIIS1201971203900567.pdf1bbf60958c3341eb500e3ec1b1a62f1dMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5043/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTPIIS1201971203900567.pdf.txtPIIS1201971203900567.pdf.txtExtracted texttext/plain28604https://repositorio.ufba.br/bitstream/ri/5043/3/PIIS1201971203900567.pdf.txt34556ff41c3ca641e6c7803632b4e346MD53ri/50432022-07-05 14:03:14.826oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:14Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?
dc.title.alternative.pt_BR.fl_str_mv International Journal of Infectious Diseases
title Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?
spellingShingle Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?
Paraná, Raymundo
title_short Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?
title_full Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?
title_fullStr Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?
title_full_unstemmed Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?
title_sort Clinical, histologic and serologic evaluation of patients with acute non-A—E hepatitis in north-eastern Brazil: is it an infectious disease?
author Paraná, Raymundo
author_facet Paraná, Raymundo
Codes, Liana
Andrade, Zilton de Araújo
Freitas, Luiz A. R. de
Jesus, Rogério Santos
Reis, Mitermayer Galvão dos
Cotrim, Helma Pinchemel
Cunha, Simone
Trepo, Christian
author_role author
author2 Codes, Liana
Andrade, Zilton de Araújo
Freitas, Luiz A. R. de
Jesus, Rogério Santos
Reis, Mitermayer Galvão dos
Cotrim, Helma Pinchemel
Cunha, Simone
Trepo, Christian
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Paraná, Raymundo
Codes, Liana
Andrade, Zilton de Araújo
Freitas, Luiz A. R. de
Jesus, Rogério Santos
Reis, Mitermayer Galvão dos
Cotrim, Helma Pinchemel
Cunha, Simone
Trepo, Christian
Paraná, Raymundo
Codes, Liana
Andrade, Zilton de Araújo
Freitas, Luiz A. R. de
Jesus, Rogério Santos
Reis, Mitermayer Galvão dos
Cotrim, Helma Pinchemel
Cunha, Simone
Trepo, Christian
description p.222—230
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2012-01-06T12:04:01Z
dc.date.available.fl_str_mv 2012-01-06T12:04:01Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5043
dc.identifier.issn.none.fl_str_mv 1201-9712
dc.identifier.number.pt_BR.fl_str_mv v. 7. n, 3.
identifier_str_mv 1201-9712
v. 7. n, 3.
url http://www.repositorio.ufba.br/ri/handle/ri/5043
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