Profile of autoantibodies in Jaccoud's arthropathy
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://www.repositorio.ufba.br/ri/handle/ri/6432 |
Resumo: | Trabalho completo: acesso restrito, p.356–360 |
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Galvão, VerenaAtta, Ajax MercêsAtta, Maria Luiza Brito de SousaMotta, Marina P.Dourado, Stella MoreiraGrimaldi, LaraSilva, Natália Oliveira eOliveira, Isabela Silva deSantiago, Mittermayer BarretoGalvão, VerenaAtta, Ajax MercêsAtta, Maria Luiza Brito de SousaMotta, Marina P.Dourado, Stella MoreiraGrimaldi, LaraSilva, Natália Oliveira eOliveira, Isabela Silva deSantiago, Mittermayer Barreto2012-07-13T19:35:21Z2009-061297-319Xhttp://www.repositorio.ufba.br/ri/handle/ri/6432v. 76, n. 4Trabalho completo: acesso restrito, p.356–360To compare the frequency of different autoantibodies in a group of patients with Jaccoud's arthropathy (JA) secondary to systemic lupus erythematosus (SLE) with those without JA. A group of SLE patients with JA was compared with another group of SLE patients without this complication, matched by age and gender, regarding the presence of autoantibodies. Antibodies to cyclical citrullinated peptides (anti-CCP) and to mutated citrullinated vimentin (anti-MCV) as well as anti-SSA/Ro, anti-SSB/La, anti-Sm and anti-RNP and anticardiolipin (aCL) antibodies were searched by ELISA, using commercial kits. Rheumatoid factor was determined by nephelometry and antinuclear and anti-dsDNA antibodies by IIF. Forty-eight individuals were included in the study, being 24 patients with JA and 24 without JA, matched by gender and age. The frequency of anti-CCP antibodies in the whole population was 12.5% (6 cases), with no difference between the 2 groups. Anti-MCV antibodies were detected in 10.4% (5 cases), being found only in those with JA (p = 0.05). There was no association between the presence of JA and aCL, anti-Sm, anti-RNP and anti-SSB/La antibodies. On the other hand, a statistically significant association between the presence of anti-dsDNA antibodies and JA was observed (p = 0.04) as well as a marginal association with a decrease in serum levels of C3 (p = 0.06). In the present study, there was an association between the presence of JA and anti-dsDNA antibodies, and anti-MCV antibodies were found only in those SLE patients with JA. Whether these antibodies have an etiopathogenic role in JA is entirely unknown.Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-07-13T19:35:20Z No. of bitstreams: 1 (121)1-s2.0-S1297319X09000049-main.pdf: 151518 bytes, checksum: 52ae2b02fda2a4c3027328c1e176f21c (MD5)Made available in DSpace on 2012-07-13T19:35:21Z (GMT). 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dc.title.pt_BR.fl_str_mv |
Profile of autoantibodies in Jaccoud's arthropathy |
dc.title.alternative.pt_BR.fl_str_mv |
Joint Bone Spine |
title |
Profile of autoantibodies in Jaccoud's arthropathy |
spellingShingle |
Profile of autoantibodies in Jaccoud's arthropathy Galvão, Verena Systemic lupus erythematosus Accoud's arthropathy Autoantibodies |
title_short |
Profile of autoantibodies in Jaccoud's arthropathy |
title_full |
Profile of autoantibodies in Jaccoud's arthropathy |
title_fullStr |
Profile of autoantibodies in Jaccoud's arthropathy |
title_full_unstemmed |
Profile of autoantibodies in Jaccoud's arthropathy |
title_sort |
Profile of autoantibodies in Jaccoud's arthropathy |
author |
Galvão, Verena |
author_facet |
Galvão, Verena Atta, Ajax Mercês Atta, Maria Luiza Brito de Sousa Motta, Marina P. Dourado, Stella Moreira Grimaldi, Lara Silva, Natália Oliveira e Oliveira, Isabela Silva de Santiago, Mittermayer Barreto |
author_role |
author |
author2 |
Atta, Ajax Mercês Atta, Maria Luiza Brito de Sousa Motta, Marina P. Dourado, Stella Moreira Grimaldi, Lara Silva, Natália Oliveira e Oliveira, Isabela Silva de Santiago, Mittermayer Barreto |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Galvão, Verena Atta, Ajax Mercês Atta, Maria Luiza Brito de Sousa Motta, Marina P. Dourado, Stella Moreira Grimaldi, Lara Silva, Natália Oliveira e Oliveira, Isabela Silva de Santiago, Mittermayer Barreto Galvão, Verena Atta, Ajax Mercês Atta, Maria Luiza Brito de Sousa Motta, Marina P. Dourado, Stella Moreira Grimaldi, Lara Silva, Natália Oliveira e Oliveira, Isabela Silva de Santiago, Mittermayer Barreto |
dc.subject.por.fl_str_mv |
Systemic lupus erythematosus Accoud's arthropathy Autoantibodies |
topic |
Systemic lupus erythematosus Accoud's arthropathy Autoantibodies |
description |
Trabalho completo: acesso restrito, p.356–360 |
publishDate |
2009 |
dc.date.issued.fl_str_mv |
2009-06 |
dc.date.accessioned.fl_str_mv |
2012-07-13T19:35:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.repositorio.ufba.br/ri/handle/ri/6432 |
dc.identifier.issn.none.fl_str_mv |
1297-319X |
dc.identifier.number.pt_BR.fl_str_mv |
v. 76, n. 4 |
identifier_str_mv |
1297-319X v. 76, n. 4 |
url |
http://www.repositorio.ufba.br/ri/handle/ri/6432 |
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eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.pt_BR.fl_str_mv |
http://dx.doi.org/10.1016/j.jbspin.2008.11.003 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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Universidade Federal da Bahia (UFBA) |
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UFBA |
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Repositório Institucional da UFBA |
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Repositório Institucional da UFBA |
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