Profile of autoantibodies in Jaccoud's arthropathy

Detalhes bibliográficos
Autor(a) principal: Galvão, Verena
Data de Publicação: 2009
Outros Autores: Atta, Ajax Mercês, Atta, Maria Luiza Brito de Sousa, Motta, Marina P., Dourado, Stella Moreira, Grimaldi, Lara, Silva, Natália Oliveira e, Oliveira, Isabela Silva de, Santiago, Mittermayer Barreto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6432
Resumo: Trabalho completo: acesso restrito, p.356–360
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spelling Galvão, VerenaAtta, Ajax MercêsAtta, Maria Luiza Brito de SousaMotta, Marina P.Dourado, Stella MoreiraGrimaldi, LaraSilva, Natália Oliveira eOliveira, Isabela Silva deSantiago, Mittermayer BarretoGalvão, VerenaAtta, Ajax MercêsAtta, Maria Luiza Brito de SousaMotta, Marina P.Dourado, Stella MoreiraGrimaldi, LaraSilva, Natália Oliveira eOliveira, Isabela Silva deSantiago, Mittermayer Barreto2012-07-13T19:35:21Z2009-061297-319Xhttp://www.repositorio.ufba.br/ri/handle/ri/6432v. 76, n. 4Trabalho completo: acesso restrito, p.356–360To compare the frequency of different autoantibodies in a group of patients with Jaccoud's arthropathy (JA) secondary to systemic lupus erythematosus (SLE) with those without JA. A group of SLE patients with JA was compared with another group of SLE patients without this complication, matched by age and gender, regarding the presence of autoantibodies. Antibodies to cyclical citrullinated peptides (anti-CCP) and to mutated citrullinated vimentin (anti-MCV) as well as anti-SSA/Ro, anti-SSB/La, anti-Sm and anti-RNP and anticardiolipin (aCL) antibodies were searched by ELISA, using commercial kits. Rheumatoid factor was determined by nephelometry and antinuclear and anti-dsDNA antibodies by IIF. Forty-eight individuals were included in the study, being 24 patients with JA and 24 without JA, matched by gender and age. The frequency of anti-CCP antibodies in the whole population was 12.5% (6 cases), with no difference between the 2 groups. Anti-MCV antibodies were detected in 10.4% (5 cases), being found only in those with JA (p = 0.05). There was no association between the presence of JA and aCL, anti-Sm, anti-RNP and anti-SSB/La antibodies. On the other hand, a statistically significant association between the presence of anti-dsDNA antibodies and JA was observed (p = 0.04) as well as a marginal association with a decrease in serum levels of C3 (p = 0.06). In the present study, there was an association between the presence of JA and anti-dsDNA antibodies, and anti-MCV antibodies were found only in those SLE patients with JA. Whether these antibodies have an etiopathogenic role in JA is entirely unknown.Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-07-13T19:35:20Z No. of bitstreams: 1 (121)1-s2.0-S1297319X09000049-main.pdf: 151518 bytes, checksum: 52ae2b02fda2a4c3027328c1e176f21c (MD5)Made available in DSpace on 2012-07-13T19:35:21Z (GMT). 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dc.title.pt_BR.fl_str_mv Profile of autoantibodies in Jaccoud's arthropathy
dc.title.alternative.pt_BR.fl_str_mv Joint Bone Spine
title Profile of autoantibodies in Jaccoud's arthropathy
spellingShingle Profile of autoantibodies in Jaccoud's arthropathy
Galvão, Verena
Systemic lupus erythematosus
Accoud's arthropathy
Autoantibodies
title_short Profile of autoantibodies in Jaccoud's arthropathy
title_full Profile of autoantibodies in Jaccoud's arthropathy
title_fullStr Profile of autoantibodies in Jaccoud's arthropathy
title_full_unstemmed Profile of autoantibodies in Jaccoud's arthropathy
title_sort Profile of autoantibodies in Jaccoud's arthropathy
author Galvão, Verena
author_facet Galvão, Verena
Atta, Ajax Mercês
Atta, Maria Luiza Brito de Sousa
Motta, Marina P.
Dourado, Stella Moreira
Grimaldi, Lara
Silva, Natália Oliveira e
Oliveira, Isabela Silva de
Santiago, Mittermayer Barreto
author_role author
author2 Atta, Ajax Mercês
Atta, Maria Luiza Brito de Sousa
Motta, Marina P.
Dourado, Stella Moreira
Grimaldi, Lara
Silva, Natália Oliveira e
Oliveira, Isabela Silva de
Santiago, Mittermayer Barreto
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Galvão, Verena
Atta, Ajax Mercês
Atta, Maria Luiza Brito de Sousa
Motta, Marina P.
Dourado, Stella Moreira
Grimaldi, Lara
Silva, Natália Oliveira e
Oliveira, Isabela Silva de
Santiago, Mittermayer Barreto
Galvão, Verena
Atta, Ajax Mercês
Atta, Maria Luiza Brito de Sousa
Motta, Marina P.
Dourado, Stella Moreira
Grimaldi, Lara
Silva, Natália Oliveira e
Oliveira, Isabela Silva de
Santiago, Mittermayer Barreto
dc.subject.por.fl_str_mv Systemic lupus erythematosus
Accoud's arthropathy
Autoantibodies
topic Systemic lupus erythematosus
Accoud's arthropathy
Autoantibodies
description Trabalho completo: acesso restrito, p.356–360
publishDate 2009
dc.date.issued.fl_str_mv 2009-06
dc.date.accessioned.fl_str_mv 2012-07-13T19:35:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6432
dc.identifier.issn.none.fl_str_mv 1297-319X
dc.identifier.number.pt_BR.fl_str_mv v. 76, n. 4
identifier_str_mv 1297-319X
v. 76, n. 4
url http://www.repositorio.ufba.br/ri/handle/ri/6432
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.jbspin.2008.11.003
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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