Profile of autoantibodies in Jaccoud's arthropathy

Detalhes bibliográficos
Autor(a) principal: Galvão, Verena
Data de Publicação: 2009
Outros Autores: Atta, Ajax Mercês, Atta, Maria Luiza Brito de Sousa, Motta, Marina P., Dourado, Stella Moreira, Grimaldi, Lara, Silva, Natália Oliveira e, Oliveira, Isabela Silva de, Santiago, Mittermayer Barreto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/6432
Resumo: Trabalho completo: acesso restrito, p.356–360
id UFBA-2_d5fb1b968531d48a6266e8d7471560b8
oai_identifier_str oai:repositorio.ufba.br:ri/6432
network_acronym_str UFBA-2
network_name_str Repositório Institucional da UFBA
repository_id_str 1932
spelling Galvão, VerenaAtta, Ajax MercêsAtta, Maria Luiza Brito de SousaMotta, Marina P.Dourado, Stella MoreiraGrimaldi, LaraSilva, Natália Oliveira eOliveira, Isabela Silva deSantiago, Mittermayer BarretoGalvão, VerenaAtta, Ajax MercêsAtta, Maria Luiza Brito de SousaMotta, Marina P.Dourado, Stella MoreiraGrimaldi, LaraSilva, Natália Oliveira eOliveira, Isabela Silva deSantiago, Mittermayer Barreto2012-07-13T19:35:21Z2009-061297-319Xhttp://www.repositorio.ufba.br/ri/handle/ri/6432v. 76, n. 4Trabalho completo: acesso restrito, p.356–360To compare the frequency of different autoantibodies in a group of patients with Jaccoud's arthropathy (JA) secondary to systemic lupus erythematosus (SLE) with those without JA. A group of SLE patients with JA was compared with another group of SLE patients without this complication, matched by age and gender, regarding the presence of autoantibodies. Antibodies to cyclical citrullinated peptides (anti-CCP) and to mutated citrullinated vimentin (anti-MCV) as well as anti-SSA/Ro, anti-SSB/La, anti-Sm and anti-RNP and anticardiolipin (aCL) antibodies were searched by ELISA, using commercial kits. Rheumatoid factor was determined by nephelometry and antinuclear and anti-dsDNA antibodies by IIF. Forty-eight individuals were included in the study, being 24 patients with JA and 24 without JA, matched by gender and age. The frequency of anti-CCP antibodies in the whole population was 12.5% (6 cases), with no difference between the 2 groups. Anti-MCV antibodies were detected in 10.4% (5 cases), being found only in those with JA (p = 0.05). There was no association between the presence of JA and aCL, anti-Sm, anti-RNP and anti-SSB/La antibodies. On the other hand, a statistically significant association between the presence of anti-dsDNA antibodies and JA was observed (p = 0.04) as well as a marginal association with a decrease in serum levels of C3 (p = 0.06). In the present study, there was an association between the presence of JA and anti-dsDNA antibodies, and anti-MCV antibodies were found only in those SLE patients with JA. Whether these antibodies have an etiopathogenic role in JA is entirely unknown.Submitted by Bruna Lessa (lessbruna@gmail.com) on 2012-07-13T19:35:20Z No. of bitstreams: 1 (121)1-s2.0-S1297319X09000049-main.pdf: 151518 bytes, checksum: 52ae2b02fda2a4c3027328c1e176f21c (MD5)Made available in DSpace on 2012-07-13T19:35:21Z (GMT). No. of bitstreams: 1 (121)1-s2.0-S1297319X09000049-main.pdf: 151518 bytes, checksum: 52ae2b02fda2a4c3027328c1e176f21c (MD5) Previous issue date: 2009-06Elsevierhttp://dx.doi.org/10.1016/j.jbspin.2008.11.003reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBASystemic lupus erythematosusAccoud's arthropathyAutoantibodiesProfile of autoantibodies in Jaccoud's arthropathyJoint Bone Spineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01enginfo:eu-repo/semantics/openAccessORIGINAL(121)1-s2.0-S1297319X09000049-main.pdf(121)1-s2.0-S1297319X09000049-main.pdfapplication/pdf151518https://repositorio.ufba.br/bitstream/ri/6432/1/%28121%291-s2.0-S1297319X09000049-main.pdf52ae2b02fda2a4c3027328c1e176f21cMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/6432/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXT(121)1-s2.0-S1297319X09000049-main.pdf.txt(121)1-s2.0-S1297319X09000049-main.pdf.txtExtracted texttext/plain23237https://repositorio.ufba.br/bitstream/ri/6432/3/%28121%291-s2.0-S1297319X09000049-main.pdf.txtc4532722b31d2bff26d03eed3bc94d51MD53ri/64322022-07-05 14:03:42.488oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:42Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Profile of autoantibodies in Jaccoud's arthropathy
dc.title.alternative.pt_BR.fl_str_mv Joint Bone Spine
title Profile of autoantibodies in Jaccoud's arthropathy
spellingShingle Profile of autoantibodies in Jaccoud's arthropathy
Galvão, Verena
Systemic lupus erythematosus
Accoud's arthropathy
Autoantibodies
title_short Profile of autoantibodies in Jaccoud's arthropathy
title_full Profile of autoantibodies in Jaccoud's arthropathy
title_fullStr Profile of autoantibodies in Jaccoud's arthropathy
title_full_unstemmed Profile of autoantibodies in Jaccoud's arthropathy
title_sort Profile of autoantibodies in Jaccoud's arthropathy
author Galvão, Verena
author_facet Galvão, Verena
Atta, Ajax Mercês
Atta, Maria Luiza Brito de Sousa
Motta, Marina P.
Dourado, Stella Moreira
Grimaldi, Lara
Silva, Natália Oliveira e
Oliveira, Isabela Silva de
Santiago, Mittermayer Barreto
author_role author
author2 Atta, Ajax Mercês
Atta, Maria Luiza Brito de Sousa
Motta, Marina P.
Dourado, Stella Moreira
Grimaldi, Lara
Silva, Natália Oliveira e
Oliveira, Isabela Silva de
Santiago, Mittermayer Barreto
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Galvão, Verena
Atta, Ajax Mercês
Atta, Maria Luiza Brito de Sousa
Motta, Marina P.
Dourado, Stella Moreira
Grimaldi, Lara
Silva, Natália Oliveira e
Oliveira, Isabela Silva de
Santiago, Mittermayer Barreto
Galvão, Verena
Atta, Ajax Mercês
Atta, Maria Luiza Brito de Sousa
Motta, Marina P.
Dourado, Stella Moreira
Grimaldi, Lara
Silva, Natália Oliveira e
Oliveira, Isabela Silva de
Santiago, Mittermayer Barreto
dc.subject.por.fl_str_mv Systemic lupus erythematosus
Accoud's arthropathy
Autoantibodies
topic Systemic lupus erythematosus
Accoud's arthropathy
Autoantibodies
description Trabalho completo: acesso restrito, p.356–360
publishDate 2009
dc.date.issued.fl_str_mv 2009-06
dc.date.accessioned.fl_str_mv 2012-07-13T19:35:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/6432
dc.identifier.issn.none.fl_str_mv 1297-319X
dc.identifier.number.pt_BR.fl_str_mv v. 76, n. 4
identifier_str_mv 1297-319X
v. 76, n. 4
url http://www.repositorio.ufba.br/ri/handle/ri/6432
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1016/j.jbspin.2008.11.003
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
instname:Universidade Federal da Bahia (UFBA)
instacron:UFBA
instname_str Universidade Federal da Bahia (UFBA)
instacron_str UFBA
institution UFBA
reponame_str Repositório Institucional da UFBA
collection Repositório Institucional da UFBA
bitstream.url.fl_str_mv https://repositorio.ufba.br/bitstream/ri/6432/1/%28121%291-s2.0-S1297319X09000049-main.pdf
https://repositorio.ufba.br/bitstream/ri/6432/2/license.txt
https://repositorio.ufba.br/bitstream/ri/6432/3/%28121%291-s2.0-S1297319X09000049-main.pdf.txt
bitstream.checksum.fl_str_mv 52ae2b02fda2a4c3027328c1e176f21c
1b89a9a0548218172d7c829f87a0eab9
c4532722b31d2bff26d03eed3bc94d51
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)
repository.mail.fl_str_mv
_version_ 1801502449959174144