Furosemide is associated with acute kidney injury in critically ill patients

Detalhes bibliográficos
Autor(a) principal: Levi, T. M.
Data de Publicação: 2012
Outros Autores: Rocha, M. S., Almeida, D. N., Martins, R. T. C., Silva, M. G. C., Santana, N. C. P., Sanjuan, I. T., Cruz, C. M. S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/15641
Resumo: p. 827-833
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spelling Levi, T. M.Rocha, M. S.Almeida, D. N.Martins, R. T. C.Silva, M. G. C.Santana, N. C. P.Sanjuan, I. T.Cruz, C. M. S.Levi, T. M.Rocha, M. S.Almeida, D. N.Martins, R. T. C.Silva, M. G. C.Santana, N. C. P.Sanjuan, I. T.Cruz, C. M. S.2014-08-18T16:41:46Z20120100-879Xhttp://repositorio.ufba.br/ri/handle/ri/15641v. 45, n. 9p. 827-833Acute kidney injury (AKI) is common in critically ill patients. Diuretics are used without any evidence demonstrating a beneficial effect on renal function. The objective of the present study is to determine the incidence of AKI in an intensive care unit (ICU) and if there is an association between the use of furosemide and the development of AKI. The study involved a hospital cohort in which 344 patients were consecutively enrolled from January 2010 to January 2011. A total of 132 patients (75 females and 57 males, average age 64 years) remained for analysis. Most exclusions were related to ICU discharge in the first 24 h. Laboratory, sociodemographic and clinical data were collected until the development of AKI, medical discharge or patient death. The incidence of AKI was 55% (95%CI = 46-64). The predictors of AKI found by univariate analysis were septic shock: OR = 3.12, 95%CI = 1.36-7.14; use of furosemide: OR = 3.27, 95%CI = 1.57-6.80, and age: OR = 1.02, 95%CI = 1.00-1.04. Analysis of the subgroup of patients with septic shock showed that the odds ratio of furosemide was 5.5 (95%CI = 1.16-26.02) for development of AKI. Age, use of furosemide, and septic shock were predictors of AKI in critically ill patients. Use of furosemide in the subgroup of patients with sepsis/septic shock increased (68.4%) the chance of development of AKI when compared to the sample as a whole (43.9%)Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2014-07-15T16:12:57Z No. of bitstreams: 1 R.T.C. Martins.pdf: 1494527 bytes, checksum: f0526d899a57a9091d70de94b3316ef1 (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2014-08-18T16:41:46Z (GMT) No. of bitstreams: 1 R.T.C. Martins.pdf: 1494527 bytes, checksum: f0526d899a57a9091d70de94b3316ef1 (MD5)Made available in DSpace on 2014-08-18T16:41:46Z (GMT). No. of bitstreams: 1 R.T.C. Martins.pdf: 1494527 bytes, checksum: f0526d899a57a9091d70de94b3316ef1 (MD5) Previous issue date: 2012http://dx.doi.org/10.1590/S0100-879X2012007500093reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAAcute renal failureCritically ill patientsFurosemideSeptic shockFurosemide is associated with acute kidney injury in critically ill patientsBrazilian Journal of Medical and Biological Researchinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALR.T.C. Martins.pdfR.T.C. 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dc.title.pt_BR.fl_str_mv Furosemide is associated with acute kidney injury in critically ill patients
dc.title.alternative.pt_BR.fl_str_mv Brazilian Journal of Medical and Biological Research
title Furosemide is associated with acute kidney injury in critically ill patients
spellingShingle Furosemide is associated with acute kidney injury in critically ill patients
Levi, T. M.
Acute renal failure
Critically ill patients
Furosemide
Septic shock
title_short Furosemide is associated with acute kidney injury in critically ill patients
title_full Furosemide is associated with acute kidney injury in critically ill patients
title_fullStr Furosemide is associated with acute kidney injury in critically ill patients
title_full_unstemmed Furosemide is associated with acute kidney injury in critically ill patients
title_sort Furosemide is associated with acute kidney injury in critically ill patients
author Levi, T. M.
author_facet Levi, T. M.
Rocha, M. S.
Almeida, D. N.
Martins, R. T. C.
Silva, M. G. C.
Santana, N. C. P.
Sanjuan, I. T.
Cruz, C. M. S.
author_role author
author2 Rocha, M. S.
Almeida, D. N.
Martins, R. T. C.
Silva, M. G. C.
Santana, N. C. P.
Sanjuan, I. T.
Cruz, C. M. S.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Levi, T. M.
Rocha, M. S.
Almeida, D. N.
Martins, R. T. C.
Silva, M. G. C.
Santana, N. C. P.
Sanjuan, I. T.
Cruz, C. M. S.
Levi, T. M.
Rocha, M. S.
Almeida, D. N.
Martins, R. T. C.
Silva, M. G. C.
Santana, N. C. P.
Sanjuan, I. T.
Cruz, C. M. S.
dc.subject.por.fl_str_mv Acute renal failure
Critically ill patients
Furosemide
Septic shock
topic Acute renal failure
Critically ill patients
Furosemide
Septic shock
description p. 827-833
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-08-18T16:41:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/15641
dc.identifier.issn.none.fl_str_mv 0100-879X
dc.identifier.number.pt_BR.fl_str_mv v. 45, n. 9
identifier_str_mv 0100-879X
v. 45, n. 9
url http://repositorio.ufba.br/ri/handle/ri/15641
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.pt_BR.fl_str_mv http://dx.doi.org/10.1590/S0100-879X2012007500093
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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