Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da Universidade Federal do Ceará (UFC) |
Texto Completo: | http://www.repositorio.ufc.br/handle/riufc/21930 |
Resumo: | Although pharmacologic treatments for central giant cell lesions have gained much emphasis, these treatment modalities do not always have successful outcomes, and surgical treatment may be necessary. The purpose of the present study was to report a case of aggressive central giant cell lesion initially treated by nonsurgical methods without satisfactory results, necessitating segmental mandibular resection for definitive treatment and oral rehabilitation. A 20-year-old woman was diagnosed with an aggressive central giant cell lesion in the mandible. The patient was first treated with intralesional corticosteroid injections. Subsequently, the lesion increased in size. Therefore, a second pharmacologic treatment was proposed with salmon calcitonin nasal spray, but no signs of a treatment response were noted. Because of the lack of response, surgical excision was performed, and a mandibular reconstruction plate was installed. At 12 months after surgical resection, the patient underwent mandibular reconstruction with bone grafts. After 6 months, 7 dental implants were installed, and fixed prostheses were made. After installation of the prostheses, the patient experienced persistent mandibular laterognathism, and a mandibular orthognathic surgery was performed to correct the laterognathia. The follow-up examination 4 years after orthognathic surgery showed no signs of recurrence and good facial symmetry. |
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Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case reportReabilitação oralCirurgia OrtognáticaAlthough pharmacologic treatments for central giant cell lesions have gained much emphasis, these treatment modalities do not always have successful outcomes, and surgical treatment may be necessary. The purpose of the present study was to report a case of aggressive central giant cell lesion initially treated by nonsurgical methods without satisfactory results, necessitating segmental mandibular resection for definitive treatment and oral rehabilitation. A 20-year-old woman was diagnosed with an aggressive central giant cell lesion in the mandible. The patient was first treated with intralesional corticosteroid injections. Subsequently, the lesion increased in size. Therefore, a second pharmacologic treatment was proposed with salmon calcitonin nasal spray, but no signs of a treatment response were noted. Because of the lack of response, surgical excision was performed, and a mandibular reconstruction plate was installed. At 12 months after surgical resection, the patient underwent mandibular reconstruction with bone grafts. After 6 months, 7 dental implants were installed, and fixed prostheses were made. After installation of the prostheses, the patient experienced persistent mandibular laterognathism, and a mandibular orthognathic surgery was performed to correct the laterognathia. The follow-up examination 4 years after orthognathic surgery showed no signs of recurrence and good facial symmetry.Journal of Oral and Maxillofacial Surgery2017-02-09T12:52:55Z2017-02-09T12:52:55Z2016-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfNOGUEIRA, R. L. M. et al. Surgical Treatment, Oral Rehabilitation, and Orthognathic Surgery. After failure of pharmacologic treatment of central giant cell lesion : a case report. Journal of Oral and Maxillofacial Surgery, Philadelphia, v. 74, n. 12, p. 2567.e1–2567.e10, dec. 2016.0278-2391http://www.repositorio.ufc.br/handle/riufc/21930Nogueira, Renato Luiz MaiaOsterne, Rafael Lima VerdeCavalcante, Roberta BarrosoAbreu, Ricardo Teixeiraengreponame:Repositório Institucional da Universidade Federal do Ceará (UFC)instname:Universidade Federal do Ceará (UFC)instacron:UFCinfo:eu-repo/semantics/openAccess2019-01-30T18:48:41Zoai:repositorio.ufc.br:riufc/21930Repositório InstitucionalPUBhttp://www.repositorio.ufc.br/ri-oai/requestbu@ufc.br || repositorio@ufc.bropendoar:2019-01-30T18:48:41Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC)false |
dc.title.none.fl_str_mv |
Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report |
title |
Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report |
spellingShingle |
Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report Nogueira, Renato Luiz Maia Reabilitação oral Cirurgia Ortognática |
title_short |
Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report |
title_full |
Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report |
title_fullStr |
Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report |
title_full_unstemmed |
Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report |
title_sort |
Surgical treatment, oral rehabilitation, and orthognathic surgery after failure of pharmacologic treatment of central giant cell lesion : a case report |
author |
Nogueira, Renato Luiz Maia |
author_facet |
Nogueira, Renato Luiz Maia Osterne, Rafael Lima Verde Cavalcante, Roberta Barroso Abreu, Ricardo Teixeira |
author_role |
author |
author2 |
Osterne, Rafael Lima Verde Cavalcante, Roberta Barroso Abreu, Ricardo Teixeira |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Nogueira, Renato Luiz Maia Osterne, Rafael Lima Verde Cavalcante, Roberta Barroso Abreu, Ricardo Teixeira |
dc.subject.por.fl_str_mv |
Reabilitação oral Cirurgia Ortognática |
topic |
Reabilitação oral Cirurgia Ortognática |
description |
Although pharmacologic treatments for central giant cell lesions have gained much emphasis, these treatment modalities do not always have successful outcomes, and surgical treatment may be necessary. The purpose of the present study was to report a case of aggressive central giant cell lesion initially treated by nonsurgical methods without satisfactory results, necessitating segmental mandibular resection for definitive treatment and oral rehabilitation. A 20-year-old woman was diagnosed with an aggressive central giant cell lesion in the mandible. The patient was first treated with intralesional corticosteroid injections. Subsequently, the lesion increased in size. Therefore, a second pharmacologic treatment was proposed with salmon calcitonin nasal spray, but no signs of a treatment response were noted. Because of the lack of response, surgical excision was performed, and a mandibular reconstruction plate was installed. At 12 months after surgical resection, the patient underwent mandibular reconstruction with bone grafts. After 6 months, 7 dental implants were installed, and fixed prostheses were made. After installation of the prostheses, the patient experienced persistent mandibular laterognathism, and a mandibular orthognathic surgery was performed to correct the laterognathia. The follow-up examination 4 years after orthognathic surgery showed no signs of recurrence and good facial symmetry. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-12 2017-02-09T12:52:55Z 2017-02-09T12:52:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
NOGUEIRA, R. L. M. et al. Surgical Treatment, Oral Rehabilitation, and Orthognathic Surgery. After failure of pharmacologic treatment of central giant cell lesion : a case report. Journal of Oral and Maxillofacial Surgery, Philadelphia, v. 74, n. 12, p. 2567.e1–2567.e10, dec. 2016. 0278-2391 http://www.repositorio.ufc.br/handle/riufc/21930 |
identifier_str_mv |
NOGUEIRA, R. L. M. et al. Surgical Treatment, Oral Rehabilitation, and Orthognathic Surgery. After failure of pharmacologic treatment of central giant cell lesion : a case report. Journal of Oral and Maxillofacial Surgery, Philadelphia, v. 74, n. 12, p. 2567.e1–2567.e10, dec. 2016. 0278-2391 |
url |
http://www.repositorio.ufc.br/handle/riufc/21930 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Journal of Oral and Maxillofacial Surgery |
publisher.none.fl_str_mv |
Journal of Oral and Maxillofacial Surgery |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da Universidade Federal do Ceará (UFC) instname:Universidade Federal do Ceará (UFC) instacron:UFC |
instname_str |
Universidade Federal do Ceará (UFC) |
instacron_str |
UFC |
institution |
UFC |
reponame_str |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
collection |
Repositório Institucional da Universidade Federal do Ceará (UFC) |
repository.name.fl_str_mv |
Repositório Institucional da Universidade Federal do Ceará (UFC) - Universidade Federal do Ceará (UFC) |
repository.mail.fl_str_mv |
bu@ufc.br || repositorio@ufc.br |
_version_ |
1809935802670514176 |