Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da Universidade Federal do Espírito Santo (riUfes) |
Texto Completo: | http://repositorio.ufes.br/handle/10/10106 |
Resumo: | The harmful effects of high consumption of alcohol are associated with the elevation of blood pressure. On the other hand, high blood pressure is the main risk factor for cardiovascular morbidity and mortality. The objective of this work is to evaluate the relationship between alcohol consumption and high blood pressure in participants of the baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Out of the 15,105 baseline participants, those with use of anti-hypertension drugs, report of bariatric surgery, body mass index lower than 18.5 and higher or equal to 40Kg/m2 , and a percentile of alcohol consumption higher than 99 were excluded. The final sample was composed of 7,655 participants, between 35 and 74 years of age, and of both genders. Socioeconomic, hemodynamic, anthropometric, health and biochemical data was collected in a standardized way in six research and education institutions. Three blood pressure measures were done, with an interval of 1 minute resting, following protocol. The casual measure was considered as the average of those two blood pressure measurements. High blood pressure was defined by ≥140 mm systolic Hg and/or ≥90 mm Hg diastolic. Alcohol consumption was investigated by applying a specific questionnaire to evaluate the type of drink, the average weekly dosage, the quantity ingested at one occasion, and the consumption with meals. Alcohol consumption was estimated in grams per week and was categorized as abstainer, excessive and moderate, and by the pattern of ingestion as excessive, episodic and with meals. For analysis, statistical tests were done; and confusion factors were identified. The linear regression and logistics models were tested, with and without co-variable adjustments, and the significance level of 5% was adopted. The average consumption of beer, wine and distilled liquor was respectively of 1.906±2.239, 462±432, and 157±174mL/week. Arond 14% presented excessive alcohol consumption, and 25.3% excessive episodic consumption. Alcohol consumption was associated to high blood pressure in men that reported moderate (OR=1.69; IC95% 1.35-2.11) and excessive (OR=2.70; IC95% 2.04-3.59) consumption. In women, this association was significant only in the excessive consumption group (OR=2.86; IC95% 1.77-4.63). A higher chance for a raise in blood pressure was found among episodic excessive drinkers with a ≥2-3x/month (OR=1.69, IC95% 1.23-2.32), 1-2x/week (OR=1.49, IC95% 1.14-.94) and nearly daily/>1x/day (OR=2.15, IC95% 1.27-3.64), and who maintained after adjustment to alcohol consumption with meals. It is therefore concluded that the consumption of alcohol beverages raises the chance of high blood pressure, especially among excessive drinkers. |
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Molina, Maria del Carmen BisiSantana, Nathália Miguel TeixeiraVelasquez Melendez, Jorge GustavoMill, José Geraldo2018-08-23T21:52:22Z2018-08-232018-08-23T21:52:22Z2017-03-24The harmful effects of high consumption of alcohol are associated with the elevation of blood pressure. On the other hand, high blood pressure is the main risk factor for cardiovascular morbidity and mortality. The objective of this work is to evaluate the relationship between alcohol consumption and high blood pressure in participants of the baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Out of the 15,105 baseline participants, those with use of anti-hypertension drugs, report of bariatric surgery, body mass index lower than 18.5 and higher or equal to 40Kg/m2 , and a percentile of alcohol consumption higher than 99 were excluded. The final sample was composed of 7,655 participants, between 35 and 74 years of age, and of both genders. Socioeconomic, hemodynamic, anthropometric, health and biochemical data was collected in a standardized way in six research and education institutions. Three blood pressure measures were done, with an interval of 1 minute resting, following protocol. The casual measure was considered as the average of those two blood pressure measurements. High blood pressure was defined by ≥140 mm systolic Hg and/or ≥90 mm Hg diastolic. Alcohol consumption was investigated by applying a specific questionnaire to evaluate the type of drink, the average weekly dosage, the quantity ingested at one occasion, and the consumption with meals. Alcohol consumption was estimated in grams per week and was categorized as abstainer, excessive and moderate, and by the pattern of ingestion as excessive, episodic and with meals. For analysis, statistical tests were done; and confusion factors were identified. The linear regression and logistics models were tested, with and without co-variable adjustments, and the significance level of 5% was adopted. The average consumption of beer, wine and distilled liquor was respectively of 1.906±2.239, 462±432, and 157±174mL/week. Arond 14% presented excessive alcohol consumption, and 25.3% excessive episodic consumption. Alcohol consumption was associated to high blood pressure in men that reported moderate (OR=1.69; IC95% 1.35-2.11) and excessive (OR=2.70; IC95% 2.04-3.59) consumption. In women, this association was significant only in the excessive consumption group (OR=2.86; IC95% 1.77-4.63). A higher chance for a raise in blood pressure was found among episodic excessive drinkers with a ≥2-3x/month (OR=1.69, IC95% 1.23-2.32), 1-2x/week (OR=1.49, IC95% 1.14-.94) and nearly daily/>1x/day (OR=2.15, IC95% 1.27-3.64), and who maintained after adjustment to alcohol consumption with meals. It is therefore concluded that the consumption of alcohol beverages raises the chance of high blood pressure, especially among excessive drinkers.Os efeitos nocivos do alto consumo de álcool associam-se com a elevação da pressão arterial. Por sua vez, a hipertensão arterial (HA) é o principal fator de risco para a morbimortalidade cardiovascular. O objetivo deste trabalho foi avaliar a relação entre o consumo de álcool e a pressão arterial em participantes da linha de base do Estudo Longitudinal de Saúde do Adulto - ELSA-Brasil. Dos 15.105 participantes da linha de base, foram excluídos aqueles com uso de medicamento anti-hipertensivo, com relato de cirurgia bariátrica, índice de massa corporal menor que 18,5 e maior ou igual a 40 kg/m2 e consumo de álcool acima do percentil 99. A amostra final foi composta por 7.655 participantes, entre 35 e 74 anos, de ambos os sexos. Dados socioeconômicos, hemodinâmicos, antropométricos, de saúde e bioquímicos foram coletados de forma padronizada em seis instituições de ensino ou pesquisa. Três medições da pressão arterial foram realizadas, com intervalo de 1 minuto e após, repouso, seguindo protocolo padrão. Foi considerada a média das duas últimas como a medida casual. A pressão arterial elevada foi definida por sistólica ≥140 mm Hg e/ou diastólica ≥90 mm Hg. O consumo de álcool foi investigado por aplicação de questionário específico avaliando o tipo de bebida, a dose média semanal, a quantidade ingerida numa mesma ocasião e o consumo junto às refeições. O consumo de álcool foi estimado em gramas por semana de álcool puro e categorizado em abstêmio, excessivo e moderado e, quanto ao padrão de ingestão, em excessivo episódico e junto às refeições. Para análise foram realizados testes estatísticos e identificados fatores de confusão. Os modelos de regressão linear e logística foram testados, com e sem ajuste por covariáveis e foi adotado nível de significância de 5%. O consumo médio de cerveja, vinho e destilado foi de 1.906±2.239, 462±432 e 157±174mL/semana, respectivamente. Cerca de 14% apresentavam consumo de álcool habitual excessivo e 25,3% excessivo episódico. O álcool associou-se à pressão arterial elevada em homens que relataram consumo moderado (OR=1,69; IC95% 1,35-2,11) e excessivo (OR=2,70; IC95% 2,04-3,59). Em mulheres, essa associação foi significativa apenas no grupo de consumo excessivo (OR=2,86; IC95% 1,77-4,63). Maiores chances de aumento da pressão arterial foram encontradas entre bebedores excessivos episódicos com consumo ≥2-3x/mês (OR=1,69, IC95% 1,23-2,32), 1-2x/semana (OR=1,49, IC95% 1,14-,94) e quase diariamente/>1x/dia (OR=2,15, IC95% 1,27-3,64), que se mantiveram após ajuste pelo consumo de bebidas junto às refeições. Dessa forma, conclui-se que o consumo de bebidas alcóolicas aumenta a chance de pressão arterial elevada, sobretudo entre os bebedores excessivos.Texthttp://repositorio.ufes.br/handle/10/10106porUniversidade Federal do Espírito SantoMestrado em Saúde ColetivaPrograma de Pós-Graduação em Saúde ColetivaUFESBRCentro de Ciências da SaúdeEthanolBlood pressureHypertensionAlcoholic beverages and drinkingBebidas alcoólicas e bebedeiraEtanolELSA BrasilÁlcoolPressão arterial - BrasilHipertensãoBebidas alcoólicasAlcoolismoSaúde Coletiva614Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da Universidade Federal do Espírito Santo (riUfes)instname:Universidade Federal do Espírito Santo (UFES)instacron:UFESORIGINALtese_10861_2015_Nathália Miguel T Santana - FAPES.pdfapplication/pdf2791772http://repositorio.ufes.br/bitstreams/a427646d-2abd-4f5b-bf0a-56dbccdd384a/download5c484a40743ed666b6a76c590d030fcfMD5110/101062024-06-27 10:59:04.082oai:repositorio.ufes.br:10/10106http://repositorio.ufes.brRepositório InstitucionalPUBhttp://repositorio.ufes.br/oai/requestopendoar:21082024-06-27T10:59:04Repositório Institucional da Universidade Federal do Espírito Santo (riUfes) - Universidade Federal do Espírito Santo (UFES)false |
dc.title.none.fl_str_mv |
Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil |
title |
Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil |
spellingShingle |
Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil Santana, Nathália Miguel Teixeira Ethanol Blood pressure Hypertension Alcoholic beverages and drinking Bebidas alcoólicas e bebedeira Etanol Saúde Coletiva ELSA Brasil Álcool Pressão arterial - Brasil Hipertensão Bebidas alcoólicas Alcoolismo 614 |
title_short |
Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil |
title_full |
Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil |
title_fullStr |
Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil |
title_full_unstemmed |
Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil |
title_sort |
Consumo de álcool e pressão arterial: resultados da linha de base do ELSA-Brasil |
author |
Santana, Nathália Miguel Teixeira |
author_facet |
Santana, Nathália Miguel Teixeira |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Molina, Maria del Carmen Bisi |
dc.contributor.author.fl_str_mv |
Santana, Nathália Miguel Teixeira |
dc.contributor.referee1.fl_str_mv |
Velasquez Melendez, Jorge Gustavo |
dc.contributor.referee2.fl_str_mv |
Mill, José Geraldo |
contributor_str_mv |
Molina, Maria del Carmen Bisi Velasquez Melendez, Jorge Gustavo Mill, José Geraldo |
dc.subject.eng.fl_str_mv |
Ethanol Blood pressure Hypertension Alcoholic beverages and drinking |
topic |
Ethanol Blood pressure Hypertension Alcoholic beverages and drinking Bebidas alcoólicas e bebedeira Etanol Saúde Coletiva ELSA Brasil Álcool Pressão arterial - Brasil Hipertensão Bebidas alcoólicas Alcoolismo 614 |
dc.subject.por.fl_str_mv |
Bebidas alcoólicas e bebedeira Etanol |
dc.subject.cnpq.fl_str_mv |
Saúde Coletiva |
dc.subject.br-rjbn.none.fl_str_mv |
ELSA Brasil Álcool Pressão arterial - Brasil Hipertensão Bebidas alcoólicas Alcoolismo |
dc.subject.udc.none.fl_str_mv |
614 |
description |
The harmful effects of high consumption of alcohol are associated with the elevation of blood pressure. On the other hand, high blood pressure is the main risk factor for cardiovascular morbidity and mortality. The objective of this work is to evaluate the relationship between alcohol consumption and high blood pressure in participants of the baseline of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Out of the 15,105 baseline participants, those with use of anti-hypertension drugs, report of bariatric surgery, body mass index lower than 18.5 and higher or equal to 40Kg/m2 , and a percentile of alcohol consumption higher than 99 were excluded. The final sample was composed of 7,655 participants, between 35 and 74 years of age, and of both genders. Socioeconomic, hemodynamic, anthropometric, health and biochemical data was collected in a standardized way in six research and education institutions. Three blood pressure measures were done, with an interval of 1 minute resting, following protocol. The casual measure was considered as the average of those two blood pressure measurements. High blood pressure was defined by ≥140 mm systolic Hg and/or ≥90 mm Hg diastolic. Alcohol consumption was investigated by applying a specific questionnaire to evaluate the type of drink, the average weekly dosage, the quantity ingested at one occasion, and the consumption with meals. Alcohol consumption was estimated in grams per week and was categorized as abstainer, excessive and moderate, and by the pattern of ingestion as excessive, episodic and with meals. For analysis, statistical tests were done; and confusion factors were identified. The linear regression and logistics models were tested, with and without co-variable adjustments, and the significance level of 5% was adopted. The average consumption of beer, wine and distilled liquor was respectively of 1.906±2.239, 462±432, and 157±174mL/week. Arond 14% presented excessive alcohol consumption, and 25.3% excessive episodic consumption. Alcohol consumption was associated to high blood pressure in men that reported moderate (OR=1.69; IC95% 1.35-2.11) and excessive (OR=2.70; IC95% 2.04-3.59) consumption. In women, this association was significant only in the excessive consumption group (OR=2.86; IC95% 1.77-4.63). A higher chance for a raise in blood pressure was found among episodic excessive drinkers with a ≥2-3x/month (OR=1.69, IC95% 1.23-2.32), 1-2x/week (OR=1.49, IC95% 1.14-.94) and nearly daily/>1x/day (OR=2.15, IC95% 1.27-3.64), and who maintained after adjustment to alcohol consumption with meals. It is therefore concluded that the consumption of alcohol beverages raises the chance of high blood pressure, especially among excessive drinkers. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017-03-24 |
dc.date.accessioned.fl_str_mv |
2018-08-23T21:52:22Z |
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2018-08-23 2018-08-23T21:52:22Z |
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masterThesis |
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http://repositorio.ufes.br/handle/10/10106 |
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http://repositorio.ufes.br/handle/10/10106 |
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por |
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openAccess |
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Text |
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Universidade Federal do Espírito Santo Mestrado em Saúde Coletiva |
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Programa de Pós-Graduação em Saúde Coletiva |
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UFES |
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BR |
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Centro de Ciências da Saúde |
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Universidade Federal do Espírito Santo Mestrado em Saúde Coletiva |
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