Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tde/843 |
Resumo: | Abdominal wall defects may occur in fairly all animal species, and frequently demand corrective surgical treatment including implants of meshes, such as polypropylene. However, this biomaterial is not free from complications, what stimulates constant researches for new biomaterials that present certain advantages. Due to its well known biocompatibility, poliHEMA hydrogel was the chosen biomaterial for experimental abdominal wall implant associated to polypropylene mesh. This essay compared tissue responses to the employment of polypropylene mesh alone (group PP) and polyHEMA Hydrogel film associated to polypropylene mesh (group PH) on the correction of induced abdominal wall defects on bitches. Twelve mongrel adult female dogs, weighting from 10 to 20 kg, were divided in two equal groups. The animals from group PP received the polypropylene mesh implant whilst those from group PH received polyHEMA hydrogel coated polypropylene mesh to replace the abdominal transverse muscle. Six animals from each group were submitted to surgical procedure to remove the meshes at 30 and 60 days of the postoperative period. Tissue repairing phenomena such as: chronic inflammatory reaction, giant cell presence (foreign body chronic granulomatous inflammatory reaction) and connective tissue proliferation were microscopically evaluated. It may be concluded that polyHEMA hydrogel as a coating agent on polypropylene mesh implanted onto abdominal wall of female dogs triggers greater deposition of type I collagen, than polypropylene mesh alone. |
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PAULO, Neusa Margaridahttp://lattes.cnpq.br/7949273598509043MOURA, Veridiana Maria Brianezi Dignani dehttp://lattes.cnpq.br/8773201078957745http://lattes.cnpq.br/2632303926331980SILVA, Daniel Barbosa da2014-07-29T15:07:31Z2011-01-212010-10-24SILVA, Daniel Barbosa da. Intraperitoneal implantation of polypropylene mesh coated hydrogel poly (2-hydroxyethyl methacrylate) in dogs - histological findings. 2010. 53 f. Dissertação (Mestrado em Ciências Agrárias - Veterinaria) - Universidade Federal de Goiás, Goiânia, 2010.http://repositorio.bc.ufg.br/tede/handle/tde/843Abdominal wall defects may occur in fairly all animal species, and frequently demand corrective surgical treatment including implants of meshes, such as polypropylene. However, this biomaterial is not free from complications, what stimulates constant researches for new biomaterials that present certain advantages. Due to its well known biocompatibility, poliHEMA hydrogel was the chosen biomaterial for experimental abdominal wall implant associated to polypropylene mesh. This essay compared tissue responses to the employment of polypropylene mesh alone (group PP) and polyHEMA Hydrogel film associated to polypropylene mesh (group PH) on the correction of induced abdominal wall defects on bitches. Twelve mongrel adult female dogs, weighting from 10 to 20 kg, were divided in two equal groups. The animals from group PP received the polypropylene mesh implant whilst those from group PH received polyHEMA hydrogel coated polypropylene mesh to replace the abdominal transverse muscle. Six animals from each group were submitted to surgical procedure to remove the meshes at 30 and 60 days of the postoperative period. Tissue repairing phenomena such as: chronic inflammatory reaction, giant cell presence (foreign body chronic granulomatous inflammatory reaction) and connective tissue proliferation were microscopically evaluated. It may be concluded that polyHEMA hydrogel as a coating agent on polypropylene mesh implanted onto abdominal wall of female dogs triggers greater deposition of type I collagen, than polypropylene mesh alone.Os defeitos na parede abdominal estão presentes em praticamente todas as espécies animais e não raro demandam tratamento cirúrgico corretivo com implantação de telas como a de polipropileno. Contudo esse biomaterial não é livre de complicações, o que impulsiona a constante pesquisa na busca de novos biomateriais que apresentem vantagens. O hidrogel de poliHEMA por ser reconhecidamente biocompatível foi o biomaterial de escolha para a implantação experimental em associação à tela de polipropileno na parede abdominal. Este estudo comparou as respostas teciduais do uso da tela de polipropileno isolada (grupo PP) e o filme de hidrogel de poliHEMA associado à tela de polipropileno (grupo PH) quando utilizados na correção de defeitos criados na parede abdominal de cadelas. Foram utilizadas 12 cadelas sem raça definida, adultas, pesando entre 10 e 20 kg, divididas em dois grupos de seis. Os animais do grupo PP receberam o implante da tela de polipropileno e os animais do grupo PH receberam a tela de polipropileno revestida de hidrogel de poliHEMA em substituição ao músculo transverso do abdome. Seis animais de cada grupo foram submetidos ao procedimento cirúrgico para a retirada das telas aos 30 e 60 dias do pós-operatório. Foram avaliados microscopicamente os fenômenos de reparo tecidual como: reação inflamatória crônica, presença de células gigantes (reação inflamatória crônica granulomatosa tipo corpo estranho), e proliferação conjuntiva. Conclui-se que o hidrogel de poliHEMA como agente de revestimento da tela de polipropileno quando implantado na parede abdominal de cadelas desencadeia maior deposição de colágeno tipo I quando comparado a tela de polipropileno isolada.Made available in DSpace on 2014-07-29T15:07:31Z (GMT). No. of bitstreams: 1 Daniel Barbosa.pdf: 1143657 bytes, checksum: d56a1f0787d16e510afed007895c5973 (MD5) Previous issue date: 2010-10-24application/pdfhttp://repositorio.bc.ufg.br/TEDE/retrieve/3630/Daniel%20Barbosa.pdf.jpgporUniversidade Federal de GoiásMestrado em Ciência AnimalUFGBRCiências Agrárias - Veterinariabiocompatibilidadebiomaterial sintéticocãoparede abdominalperitônio1. Implante intraperitonial em cães aspecto histológico 2. Cirurgia em animaisabdominal wallbiocompatibilitydogperitoneumsynthetic biomaterialCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMALImplante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológicoIntraperitoneal implantation of polypropylene mesh coated hydrogel poly (2-hydroxyethyl methacrylate) in dogs - histological findingsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGORIGINALDaniel Barbosa.pdfapplication/pdf1143657http://repositorio.bc.ufg.br/tede/bitstreams/337e6314-5e81-4a07-80b9-91e61c544aa5/downloadd56a1f0787d16e510afed007895c5973MD51TEXTDaniel Barbosa.pdf.txtDaniel Barbosa.pdf.txtExtracted Texttext/plain86380http://repositorio.bc.ufg.br/tede/bitstreams/8e0eb858-f61c-4ce2-be43-19d270203abc/download3252f33d2e54b5c3b7ab83ba1ad30c0cMD52THUMBNAILDaniel Barbosa.pdf.jpgDaniel Barbosa.pdf.jpgGenerated Thumbnailimage/jpeg1950http://repositorio.bc.ufg.br/tede/bitstreams/cb623668-fc68-4ee6-99ee-21aeaed10b95/download59b831d80f43529fb923d8802af7e34fMD53tde/8432014-07-30 03:07:02.587open.accessoai:repositorio.bc.ufg.br:tde/843http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2014-07-30T06:07:02Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)false |
dc.title.por.fl_str_mv |
Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico |
dc.title.alternative.eng.fl_str_mv |
Intraperitoneal implantation of polypropylene mesh coated hydrogel poly (2-hydroxyethyl methacrylate) in dogs - histological findings |
title |
Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico |
spellingShingle |
Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico SILVA, Daniel Barbosa da biocompatibilidade biomaterial sintético cão parede abdominal peritônio 1. Implante intraperitonial em cães aspecto histológico 2. Cirurgia em animais abdominal wall biocompatibility dog peritoneum synthetic biomaterial CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL |
title_short |
Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico |
title_full |
Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico |
title_fullStr |
Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico |
title_full_unstemmed |
Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico |
title_sort |
Implante intraperitonial de tela de polipropileno revestida de hidrogel de poli (2-hidroxietil metacrilato) em cães aspecto histológico |
author |
SILVA, Daniel Barbosa da |
author_facet |
SILVA, Daniel Barbosa da |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
PAULO, Neusa Margarida |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/7949273598509043 |
dc.contributor.advisor-co1.fl_str_mv |
MOURA, Veridiana Maria Brianezi Dignani de |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/8773201078957745 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/2632303926331980 |
dc.contributor.author.fl_str_mv |
SILVA, Daniel Barbosa da |
contributor_str_mv |
PAULO, Neusa Margarida MOURA, Veridiana Maria Brianezi Dignani de |
dc.subject.por.fl_str_mv |
biocompatibilidade biomaterial sintético cão parede abdominal peritônio 1. Implante intraperitonial em cães aspecto histológico 2. Cirurgia em animais |
topic |
biocompatibilidade biomaterial sintético cão parede abdominal peritônio 1. Implante intraperitonial em cães aspecto histológico 2. Cirurgia em animais abdominal wall biocompatibility dog peritoneum synthetic biomaterial CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL |
dc.subject.eng.fl_str_mv |
abdominal wall biocompatibility dog peritoneum synthetic biomaterial |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL |
description |
Abdominal wall defects may occur in fairly all animal species, and frequently demand corrective surgical treatment including implants of meshes, such as polypropylene. However, this biomaterial is not free from complications, what stimulates constant researches for new biomaterials that present certain advantages. Due to its well known biocompatibility, poliHEMA hydrogel was the chosen biomaterial for experimental abdominal wall implant associated to polypropylene mesh. This essay compared tissue responses to the employment of polypropylene mesh alone (group PP) and polyHEMA Hydrogel film associated to polypropylene mesh (group PH) on the correction of induced abdominal wall defects on bitches. Twelve mongrel adult female dogs, weighting from 10 to 20 kg, were divided in two equal groups. The animals from group PP received the polypropylene mesh implant whilst those from group PH received polyHEMA hydrogel coated polypropylene mesh to replace the abdominal transverse muscle. Six animals from each group were submitted to surgical procedure to remove the meshes at 30 and 60 days of the postoperative period. Tissue repairing phenomena such as: chronic inflammatory reaction, giant cell presence (foreign body chronic granulomatous inflammatory reaction) and connective tissue proliferation were microscopically evaluated. It may be concluded that polyHEMA hydrogel as a coating agent on polypropylene mesh implanted onto abdominal wall of female dogs triggers greater deposition of type I collagen, than polypropylene mesh alone. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010-10-24 |
dc.date.available.fl_str_mv |
2011-01-21 |
dc.date.accessioned.fl_str_mv |
2014-07-29T15:07:31Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
SILVA, Daniel Barbosa da. Intraperitoneal implantation of polypropylene mesh coated hydrogel poly (2-hydroxyethyl methacrylate) in dogs - histological findings. 2010. 53 f. Dissertação (Mestrado em Ciências Agrárias - Veterinaria) - Universidade Federal de Goiás, Goiânia, 2010. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tde/843 |
identifier_str_mv |
SILVA, Daniel Barbosa da. Intraperitoneal implantation of polypropylene mesh coated hydrogel poly (2-hydroxyethyl methacrylate) in dogs - histological findings. 2010. 53 f. Dissertação (Mestrado em Ciências Agrárias - Veterinaria) - Universidade Federal de Goiás, Goiânia, 2010. |
url |
http://repositorio.bc.ufg.br/tede/handle/tde/843 |
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por |
language |
por |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Mestrado em Ciência Animal |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
BR |
dc.publisher.department.fl_str_mv |
Ciências Agrárias - Veterinaria |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
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Universidade Federal de Goiás (UFG) |
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UFG |
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UFG |
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Repositório Institucional da UFG |
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