Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Ciência animal brasileira (Online) |
Texto Completo: | https://revistas.ufg.br/vet/article/view/74134 |
Resumo: | Good Laboratory Practice (GLP) is a management quality control system that encompasses the organizational process and conditions under which non-clinical health and environmental studies are carried out. According to the World Health Organization, GLP must contain five topics: resources, characterization, rules, results, and quality control. The aim of this work is to address a review according to WHO standard to the implementation of Good Laboratory Practices in zebrafish (Danio rerio) facility. Considering that the promotion of one health (animal, human, and environmental) associated with an education plan, protocols, and records are fundamental to guarantee the safety and integrity of employees, animals and the environment as well as reliability in the results generated. In a way, Brazil still needs improvements related to the wellfare of aquatic organisms (national laws, international agreements, corporate programs, and others); especially in relation to its use in research and technological development. In this way, the implementation of GLPs provide valuable guidance for improving animal welfare and worker safety, facilitating the standardization of research.Keywords: Danio rerio; standardization; welfare; regulatory guidelines; legislation. |
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Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratoriesBoas práticas na criação e manutenção de zebrafish (Danio rerio) em laboratório no BrasilGood Laboratory Practice (GLP) is a management quality control system that encompasses the organizational process and conditions under which non-clinical health and environmental studies are carried out. According to the World Health Organization, GLP must contain five topics: resources, characterization, rules, results, and quality control. The aim of this work is to address a review according to WHO standard to the implementation of Good Laboratory Practices in zebrafish (Danio rerio) facility. Considering that the promotion of one health (animal, human, and environmental) associated with an education plan, protocols, and records are fundamental to guarantee the safety and integrity of employees, animals and the environment as well as reliability in the results generated. In a way, Brazil still needs improvements related to the wellfare of aquatic organisms (national laws, international agreements, corporate programs, and others); especially in relation to its use in research and technological development. In this way, the implementation of GLPs provide valuable guidance for improving animal welfare and worker safety, facilitating the standardization of research.Keywords: Danio rerio; standardization; welfare; regulatory guidelines; legislation. As Boas Práticas de Laboratório (BPL) são um sistema de controle de qualidade gerencial que abrange o processo organizacional e as condições sob as quais os estudos não clínicos de saúde e meio ambiente são desenvolvidos. Conforme a Organização Mundial da Saúde (OMS) as BPL devem conter cinco tópicos: recursos, caracterização, regras, resultados e controle de qualidade. O objetivo deste trabalho foi apresentar uma revisão conforme o padrão da OMS para a implementação das BPL em biotério de zebrafish. Considerando que a promoção da saúde única (animal, humana e ambiental) associada a um plano de educação, protocolos e registros são fundamentais para garantir a segurança e a integridade dos trabalhadores/pesquisadores, animais e meio ambiente assim como confiabilidade nos resultados gerados. De certa forma o Brasil ainda necessita de melhorias relacionadas ao bem-estar de organismos aquáticos (leis nacionais, acordos internacionais, programas corporativos e outros); especialmente em relação à utilização destes na pesquisa e desenvolvimento tecnológico. Desta forma, a implementação de BPL fornece uma orientação valiosa para a melhoria do bem-estar animal, e segurança do trabalhador vindo a facilitar a padronização da pesquisa.Palavras-chave: Danio rerio; padronização; bem-estar; diretrizes reguladoras; legislação.Universidade Federal de Goiás2023-01-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://revistas.ufg.br/vet/article/view/74134Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 24 (2023): Continuous publicationCiência Animal Brasileira / Brazilian Animal Science; v. 24 (2023): Publicação contínua1809-68911518-2797reponame:Ciência animal brasileira (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporenghttps://revistas.ufg.br/vet/article/view/74134/39351https://revistas.ufg.br/vet/article/view/74134/39605https://revistas.ufg.br/vet/article/view/74134/39352https://revistas.ufg.br/vet/article/view/74134/39606Copyright (c) 2023 Ciência Animal Brasileira / Brazilian Animal Sciencehttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessTavares Kütter, MateusJose Gil Barcellos, LeonardoBoyle, Robert TewMarins, Luis FernandoRezende da Silveira, Tony Leandro2023-08-24T18:50:56Zoai:ojs.revistas.ufg.br:article/74134Revistahttps://revistas.ufg.br/vetPUBhttps://revistas.ufg.br/vet/oai||revistacab@gmail.com1809-68911518-2797opendoar:2024-05-21T19:56:33.324211Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG)true |
dc.title.none.fl_str_mv |
Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories Boas práticas na criação e manutenção de zebrafish (Danio rerio) em laboratório no Brasil |
title |
Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories |
spellingShingle |
Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories Tavares Kütter, Mateus |
title_short |
Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories |
title_full |
Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories |
title_fullStr |
Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories |
title_full_unstemmed |
Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories |
title_sort |
Good practices in the rearing and maintenance of zebrafish (Danio rerio) in Brazilian laboratories |
author |
Tavares Kütter, Mateus |
author_facet |
Tavares Kütter, Mateus Jose Gil Barcellos, Leonardo Boyle, Robert Tew Marins, Luis Fernando Rezende da Silveira, Tony Leandro |
author_role |
author |
author2 |
Jose Gil Barcellos, Leonardo Boyle, Robert Tew Marins, Luis Fernando Rezende da Silveira, Tony Leandro |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Tavares Kütter, Mateus Jose Gil Barcellos, Leonardo Boyle, Robert Tew Marins, Luis Fernando Rezende da Silveira, Tony Leandro |
description |
Good Laboratory Practice (GLP) is a management quality control system that encompasses the organizational process and conditions under which non-clinical health and environmental studies are carried out. According to the World Health Organization, GLP must contain five topics: resources, characterization, rules, results, and quality control. The aim of this work is to address a review according to WHO standard to the implementation of Good Laboratory Practices in zebrafish (Danio rerio) facility. Considering that the promotion of one health (animal, human, and environmental) associated with an education plan, protocols, and records are fundamental to guarantee the safety and integrity of employees, animals and the environment as well as reliability in the results generated. In a way, Brazil still needs improvements related to the wellfare of aquatic organisms (national laws, international agreements, corporate programs, and others); especially in relation to its use in research and technological development. In this way, the implementation of GLPs provide valuable guidance for improving animal welfare and worker safety, facilitating the standardization of research.Keywords: Danio rerio; standardization; welfare; regulatory guidelines; legislation. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-01-09 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revistas.ufg.br/vet/article/view/74134 |
url |
https://revistas.ufg.br/vet/article/view/74134 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
https://revistas.ufg.br/vet/article/view/74134/39351 https://revistas.ufg.br/vet/article/view/74134/39605 https://revistas.ufg.br/vet/article/view/74134/39352 https://revistas.ufg.br/vet/article/view/74134/39606 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2023 Ciência Animal Brasileira / Brazilian Animal Science http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2023 Ciência Animal Brasileira / Brazilian Animal Science http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
Brazilian Animal Science/ Ciência Animal Brasileira; Vol. 24 (2023): Continuous publication Ciência Animal Brasileira / Brazilian Animal Science; v. 24 (2023): Publicação contínua 1809-6891 1518-2797 reponame:Ciência animal brasileira (Online) instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Ciência animal brasileira (Online) |
collection |
Ciência animal brasileira (Online) |
repository.name.fl_str_mv |
Ciência animal brasileira (Online) - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
||revistacab@gmail.com |
_version_ |
1799874791127121920 |