Ácido guanidinoacético para leitões

Detalhes bibliográficos
Autor(a) principal: Teixeira, Karla Andrade
Data de Publicação: 2016
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFG
Texto Completo: http://repositorio.bc.ufg.br/tede/handle/tede/6078
Resumo: In the search for improved animal performance, has been testing new substances and new products to be used as additives in feed. Creatine and their precursors are examples of such compounds used for improvement of animal productivity. The guanidinoacetic acid is a natural precursor of creatine that has been studied in order to verify their effects on animal performance. With the objective of verify whether supplementation of guanidinoacetic acid in diets could help save the arginine used for the synthesis of creatine, which can be diverted to protein synthesis, growth and development of the animal. 90 piglets weaned at 21 days of age were used. The animals were distributed in a randomized block design based on the initial weight of the animals, with five treatments (0.00, 0.05, 0.10, 0.15 and 0.20% of inclusion of guanidinoacetic acid) six replicates and three animals per experimental unit. The experimental diets and water were fed ad libitum in the pre-initial I phase (21 -32 days old) and pre-initial II (33-42 days old), and the initial phase (43-63 days old). At 42 and 63 days old blood was collected from an animal for experimental unit to analyze creatinine and creatine kinase. They were analyzed daily weight gain, daily feed intake and feed conversion in phases pre-initial (21-42 days old), initial (43-63 days old) and the total duration of the experiment (21-63 days old). All variables were subjected to analysis of variance and regression analysis. It was adopted α = 0.05 and considered trend between α 0,05 and 0,10. In the pre-initial phase (21-42 days), there was a tendency to parameter gain weight daily (P= 0,069), however daily feed intake and feed conversion were not affected significantly by the addition of different levels of guanidinoacetic acid in the diet. As for the blood variables, creatinine levels both at 42 as at 63 days were not significantly affected. For creatine kinase levels at 42 days there was a tendency (P = 0.077), but after 63 days there were significant influences. In the initial phase (43-63 days) and total experimental period (21-63 days) were no significant effects of the inclusion of guanidinoacetic acid, both for performance variables as for creatinine and creatine kinase.
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spelling Mascarenhas, Alessandra Gimenezhttp://lattes.cnpq.br/9082632592936909Mello, Heloisa Helena de Carvalhohttp://lattes.cnpq.br/5510965166352073Arnhold, Emmanuelhttp://lattes.cnpq.br/7156945506134934Mascarenhas, Alessandra GimenezCarvalho, Thony de AssisCampos, Melissa Selaysin Dihttp://lattes.cnpq.br/2156894812263058Teixeira, Karla Andrade2016-09-01T12:17:22Z2016-03-15TEIXEIRA, K. A. Ácido guanidinoacético para leitões. 2016. 46 f. Dissertação (Mestrado em Zootecnia) - Universidade Federal de Goiás, Goiânia, 2016.http://repositorio.bc.ufg.br/tede/handle/tede/6078In the search for improved animal performance, has been testing new substances and new products to be used as additives in feed. Creatine and their precursors are examples of such compounds used for improvement of animal productivity. The guanidinoacetic acid is a natural precursor of creatine that has been studied in order to verify their effects on animal performance. With the objective of verify whether supplementation of guanidinoacetic acid in diets could help save the arginine used for the synthesis of creatine, which can be diverted to protein synthesis, growth and development of the animal. 90 piglets weaned at 21 days of age were used. The animals were distributed in a randomized block design based on the initial weight of the animals, with five treatments (0.00, 0.05, 0.10, 0.15 and 0.20% of inclusion of guanidinoacetic acid) six replicates and three animals per experimental unit. The experimental diets and water were fed ad libitum in the pre-initial I phase (21 -32 days old) and pre-initial II (33-42 days old), and the initial phase (43-63 days old). At 42 and 63 days old blood was collected from an animal for experimental unit to analyze creatinine and creatine kinase. They were analyzed daily weight gain, daily feed intake and feed conversion in phases pre-initial (21-42 days old), initial (43-63 days old) and the total duration of the experiment (21-63 days old). All variables were subjected to analysis of variance and regression analysis. It was adopted α = 0.05 and considered trend between α 0,05 and 0,10. In the pre-initial phase (21-42 days), there was a tendency to parameter gain weight daily (P= 0,069), however daily feed intake and feed conversion were not affected significantly by the addition of different levels of guanidinoacetic acid in the diet. As for the blood variables, creatinine levels both at 42 as at 63 days were not significantly affected. For creatine kinase levels at 42 days there was a tendency (P = 0.077), but after 63 days there were significant influences. In the initial phase (43-63 days) and total experimental period (21-63 days) were no significant effects of the inclusion of guanidinoacetic acid, both for performance variables as for creatinine and creatine kinase.Na busca por um melhor desempenho dos animais, vem se testando novas substâncias e novos produtos a serem utilizados como aditivos nas rações. A creatina e seus precursores são exemplos destes compostos utilizados para melhora da produtividade dos animais. O ácido guanidinoacético é um precursor natural da creatina que tem sido estudado no intuito de verificar seus efeitos sobre o desempenho do animal. Foi realizado um experimento com o objetivo de verificar se a suplementação de ácido guanidinoacético nas rações pré-iniciais de leitões poderia ajudar a poupar a arginina utilizada para a síntese de creatina, podendo ser desviada para síntese proteica, crescimento e desenvolvimento do animal. Foram utilizados 90 leitões machos castrados, desmamados aos 21 dias de idade. Os animais foram distribuídos em delineamento em blocos casualizados com base no peso inicial dos animais, com cinco tratamentos (0; 0,05; 0,10, 0,15 e 0,20% de inclusão do ácido guanidinoacético), seis repetições e três animais por unidade experimental. As rações experimentais e água foram fornecidas à vontade nas fases pré-inicial I (21 a 32 dias de idade) e pré-inicial II (33 a 42 dias de idade), e na fase inicial (43 a 63 dias de idade). Aos 42 e aos 63 dias de idade foi coletado sangue de um animal por unidade experimental para análise de creatinina e creatina quinase. Foram analisadas ganho de peso diário, consumo de ração diário e conversão alimentar nas fases pré-inicial (21-42 dias), inicial (43-63 dias) e no período total do experimento (21-63 dias). Todas as variáveis foram submetidas à análise de variância e à análise de regressão. Foi adotado α = 0,05 e considerado tendência α entre 0,05 e 0,10. Na fase pré-inicial (21-42 dias), ocorreu tendência para o parâmetro de ganho de peso diário (P= 0,069), porem consumo de ração diário e conversão alimentar não foram influenciados significativamente pela adição de diferentes níveis de ácido guanidinoacético na dieta. Já para as variáveis sanguíneas, os níveis de creatinina tanto aos 42 quanto aos 63 dias não foram influenciados significativamente. Para os níveis de creatina quinase aos 42 dias houve tendência (P=0,077), mas aos 63 dias houve influencia significativa. Na fase inicial (43-63 dias) e período total do experimento (21-63 dias), não foram observados efeitos significativos da inclusão de ácido guanidinoacético, tanto para as variáveis de desempenho quanto para creatinina e creatina quinase.Submitted by Cássia Santos (cassia.bcufg@gmail.com) on 2016-09-01T10:34:42Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertação - Karla Andrade Teixeira - 2016.pdf: 1020358 bytes, checksum: 6fcc37b871d6e8bb948ad3df803def3c (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-09-01T12:17:22Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertação - Karla Andrade Teixeira - 2016.pdf: 1020358 bytes, checksum: 6fcc37b871d6e8bb948ad3df803def3c (MD5)Made available in DSpace on 2016-09-01T12:17:22Z (GMT). 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dc.title.por.fl_str_mv Ácido guanidinoacético para leitões
dc.title.alternative.eng.fl_str_mv Guanidinoacetic acid piglets
title Ácido guanidinoacético para leitões
spellingShingle Ácido guanidinoacético para leitões
Teixeira, Karla Andrade
Arginina
Creatina
Desempenho
Suínos
Suplementação
Arginine
Creatine
Performance
Pigs
Supplementation
ZOOTECNIA::PRODUCAO ANIMAL
title_short Ácido guanidinoacético para leitões
title_full Ácido guanidinoacético para leitões
title_fullStr Ácido guanidinoacético para leitões
title_full_unstemmed Ácido guanidinoacético para leitões
title_sort Ácido guanidinoacético para leitões
author Teixeira, Karla Andrade
author_facet Teixeira, Karla Andrade
author_role author
dc.contributor.advisor1.fl_str_mv Mascarenhas, Alessandra Gimenez
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9082632592936909
dc.contributor.advisor-co1.fl_str_mv Mello, Heloisa Helena de Carvalho
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/5510965166352073
dc.contributor.advisor-co2.fl_str_mv Arnhold, Emmanuel
dc.contributor.advisor-co2Lattes.fl_str_mv http://lattes.cnpq.br/7156945506134934
dc.contributor.referee1.fl_str_mv Mascarenhas, Alessandra Gimenez
dc.contributor.referee2.fl_str_mv Carvalho, Thony de Assis
dc.contributor.referee3.fl_str_mv Campos, Melissa Selaysin Di
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2156894812263058
dc.contributor.author.fl_str_mv Teixeira, Karla Andrade
contributor_str_mv Mascarenhas, Alessandra Gimenez
Mello, Heloisa Helena de Carvalho
Arnhold, Emmanuel
Mascarenhas, Alessandra Gimenez
Carvalho, Thony de Assis
Campos, Melissa Selaysin Di
dc.subject.por.fl_str_mv Arginina
Creatina
Desempenho
Suínos
Suplementação
topic Arginina
Creatina
Desempenho
Suínos
Suplementação
Arginine
Creatine
Performance
Pigs
Supplementation
ZOOTECNIA::PRODUCAO ANIMAL
dc.subject.eng.fl_str_mv Arginine
Creatine
Performance
Pigs
Supplementation
dc.subject.cnpq.fl_str_mv ZOOTECNIA::PRODUCAO ANIMAL
description In the search for improved animal performance, has been testing new substances and new products to be used as additives in feed. Creatine and their precursors are examples of such compounds used for improvement of animal productivity. The guanidinoacetic acid is a natural precursor of creatine that has been studied in order to verify their effects on animal performance. With the objective of verify whether supplementation of guanidinoacetic acid in diets could help save the arginine used for the synthesis of creatine, which can be diverted to protein synthesis, growth and development of the animal. 90 piglets weaned at 21 days of age were used. The animals were distributed in a randomized block design based on the initial weight of the animals, with five treatments (0.00, 0.05, 0.10, 0.15 and 0.20% of inclusion of guanidinoacetic acid) six replicates and three animals per experimental unit. The experimental diets and water were fed ad libitum in the pre-initial I phase (21 -32 days old) and pre-initial II (33-42 days old), and the initial phase (43-63 days old). At 42 and 63 days old blood was collected from an animal for experimental unit to analyze creatinine and creatine kinase. They were analyzed daily weight gain, daily feed intake and feed conversion in phases pre-initial (21-42 days old), initial (43-63 days old) and the total duration of the experiment (21-63 days old). All variables were subjected to analysis of variance and regression analysis. It was adopted α = 0.05 and considered trend between α 0,05 and 0,10. In the pre-initial phase (21-42 days), there was a tendency to parameter gain weight daily (P= 0,069), however daily feed intake and feed conversion were not affected significantly by the addition of different levels of guanidinoacetic acid in the diet. As for the blood variables, creatinine levels both at 42 as at 63 days were not significantly affected. For creatine kinase levels at 42 days there was a tendency (P = 0.077), but after 63 days there were significant influences. In the initial phase (43-63 days) and total experimental period (21-63 days) were no significant effects of the inclusion of guanidinoacetic acid, both for performance variables as for creatinine and creatine kinase.
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-09-01T12:17:22Z
dc.date.issued.fl_str_mv 2016-03-15
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.citation.fl_str_mv TEIXEIRA, K. A. Ácido guanidinoacético para leitões. 2016. 46 f. Dissertação (Mestrado em Zootecnia) - Universidade Federal de Goiás, Goiânia, 2016.
dc.identifier.uri.fl_str_mv http://repositorio.bc.ufg.br/tede/handle/tede/6078
identifier_str_mv TEIXEIRA, K. A. Ácido guanidinoacético para leitões. 2016. 46 f. Dissertação (Mestrado em Zootecnia) - Universidade Federal de Goiás, Goiânia, 2016.
url http://repositorio.bc.ufg.br/tede/handle/tede/6078
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dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Escola de Veterinária e Zootecnia - EVZ (RG)
publisher.none.fl_str_mv Universidade Federal de Goiás
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