Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFG |
Texto Completo: | http://repositorio.bc.ufg.br/tede/handle/tede/8668 |
Resumo: | Background: Some studies relate the use of paracetamol with the exacerbation of asthma symptoms and other respiratory problems. Other studies are inconclusive or deny this correlation. This makes the association between paracetamol and airway hypersensitivity very controversial and still under debate. Objectives: To investigate the effect of chronic treatment with paracetamol on rats on the contraction and relaxation of isolated airways. Methods: Wistar rats were divided into 2 groups (n = 5-8). One group was treated for 2 weeks with paracetamol (400 mg / kg, v.o.) in drinking water and another control group (pure water). The animals were euthanized after two weeks, blood was collected for biochemical analyzes (ALT, AST, TBARs reaction) and tracheal rings were isolated and prepared in an organ bath to measure the isometric tension against contractile stimuli (concentration- effect for carbachol and KCl, concentration- 2+ effect curve for Ca stimulated with carbachol or KCl) and relaxants (isoprenaline, sodium nitroprusside and verapamil). Results: Liver enzymes ALT, AST and lipid peroxidation (TBARs) were significantly increased after paracetamol treatment. Acupuncture of the airway tracheal smooth muscle response does not present any alteration, either to the contractile or relaxing stimulus, for example: cholinergic agonist, membrane 2+ 2+ 2+ depolarization, Ca influx by the sarcolemma, internal release of Ca from the sarcoplasmic reticulum, Ca , β-receptor agonist or NO donor-induced relaxation. Conclusion: Chronic treatment with paracetamol does not induce hyper or hyporeativity of the airways isolated from rats. |
id |
UFG-2_34ddc2d1e734a3ba21e30738ca97ef9f |
---|---|
oai_identifier_str |
oai:repositorio.bc.ufg.br:tede/8668 |
network_acronym_str |
UFG-2 |
network_name_str |
Repositório Institucional da UFG |
repository_id_str |
|
spelling |
Rocha, Matheus Lavorentihttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4779402Y9Castro, Patrícia Ferreira da Silvahttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4217585J1Rocha, Matheus LavorentiSilva, Vinícius Barreto daOliveira, Gisele Augusto Rodrigues deSantos, Luciano da Ressurreiçãohttp://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K8160397P6Ribeiro, Marco Túlio Lacerda2018-07-09T11:27:43Z2018-06-19RIBEIRO, M. T. L. Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos. 2018. 56 f. Dissertação (Mestrado em Ciências Farmacêuticas) - Universidade Federal de Goiás, Goiânia, 2018.http://repositorio.bc.ufg.br/tede/handle/tede/8668Background: Some studies relate the use of paracetamol with the exacerbation of asthma symptoms and other respiratory problems. Other studies are inconclusive or deny this correlation. This makes the association between paracetamol and airway hypersensitivity very controversial and still under debate. Objectives: To investigate the effect of chronic treatment with paracetamol on rats on the contraction and relaxation of isolated airways. Methods: Wistar rats were divided into 2 groups (n = 5-8). One group was treated for 2 weeks with paracetamol (400 mg / kg, v.o.) in drinking water and another control group (pure water). The animals were euthanized after two weeks, blood was collected for biochemical analyzes (ALT, AST, TBARs reaction) and tracheal rings were isolated and prepared in an organ bath to measure the isometric tension against contractile stimuli (concentration- effect for carbachol and KCl, concentration- 2+ effect curve for Ca stimulated with carbachol or KCl) and relaxants (isoprenaline, sodium nitroprusside and verapamil). Results: Liver enzymes ALT, AST and lipid peroxidation (TBARs) were significantly increased after paracetamol treatment. Acupuncture of the airway tracheal smooth muscle response does not present any alteration, either to the contractile or relaxing stimulus, for example: cholinergic agonist, membrane 2+ 2+ 2+ depolarization, Ca influx by the sarcolemma, internal release of Ca from the sarcoplasmic reticulum, Ca , β-receptor agonist or NO donor-induced relaxation. Conclusion: Chronic treatment with paracetamol does not induce hyper or hyporeativity of the airways isolated from rats.Introdução: Alguns estudos relacionam o uso de paracetamol com a exacerbação dos sintomas da asma e outros problemas respiratórios. Outros estudos não são conclusivos ou negam essa correlação. Isso torna a associação entre o paracetamol e a hipersensibilidade das vias aéreas muito controversa e ainda em debate. Objetivos: Investigar o efeito do tratamento crônico com paracetamol em ratos sobre a contração e relaxamento de vias aéreas isoladas. Métodos: Ratos Wistar foram divididos em 2 grupos (n=5-8). Um grupo foi tratado por 2 semanas com paracetamol (400 mg/Kg, v.o.) na água de beber e outro, o grupo controle, foi tratado apenas com água potável. Os animais foram eutanasiados após duas semanas, o sangue foi coletado para análises bioquímicas (ALT, AST, reação de TBARs) e os aneis de traqueias foram isolados e preparados em banho de órgãos para medir a tensão isométrica mediante estímulos contráteis 2+ (curva concentração-efeito para carbacol e KCl; curva concentração-efeito para Ca estimulados com carbacol ou KCl) e relaxantes (isoprenalina, nitroprussiato de sódio e verapamil). Resultados: As enzimas hepáticas ALT, AST e a peroxidação lipídica (TBARs) foram significativamente aumentadas após o tratamento com paracetamol. A capacidade de resposta do músculo liso traqueal das vias aéreas não apresentam qualquer alteração, seja ao estímulo contrátil ou relaxante, como exemplo: agonista 2+ 2+ colinérgico, despolarização da membrana, influxo de Ca pelo sarcolema, liberação interna de Ca do 2+ retículo sarcoplásmico, bloqueio do canal Ca , agonista de receptores β ou relaxamento induzido por doador de NO. Conclusão: O tratamento crônico com paracetamol não induz a hiper ou hiporreatividade das vias aéreas isoladas de ratos.Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2018-07-09T11:18:39Z No. of bitstreams: 2 Dissertação - Marco Túlio Lacerda Ribeiro - 2018.pdf: 1380967 bytes, checksum: 194ed48e2af9c60ef94be3f60db75ef7 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2018-07-09T11:27:43Z (GMT) No. of bitstreams: 2 Dissertação - Marco Túlio Lacerda Ribeiro - 2018.pdf: 1380967 bytes, checksum: 194ed48e2af9c60ef94be3f60db75ef7 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2018-07-09T11:27:43Z (GMT). No. of bitstreams: 2 Dissertação - Marco Túlio Lacerda Ribeiro - 2018.pdf: 1380967 bytes, checksum: 194ed48e2af9c60ef94be3f60db75ef7 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2018-06-19Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal de GoiásPrograma de Pós-graduação em Ciências Farmacêuticas (FF)UFGBrasilFaculdade Farmácia - FF (RG)http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessParacetamolMúsculo lisoTraqueiaAsmaEstresse oxidativoParacetamolSmooth muscleTracheaAsthmaOxidative stressFARMACOLOGIA::FARMACOLOGIA GERALEfeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratosEffect of chronic treatment with paracetamol on the airway reactivity isolated from ratsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis8249369881961524126006006006006010281161524209375-39594841539407582472075167498588264571reponame:Repositório Institucional da UFGinstname:Universidade Federal de Goiás (UFG)instacron:UFGLICENSElicense.txtlicense.txttext/plain; charset=utf-82165http://repositorio.bc.ufg.br/tede/bitstreams/a8727cdc-425e-44c7-a6f9-237a8cd24703/downloadbd3efa91386c1718a7f26a329fdcb468MD51CC-LICENSElicense_urllicense_urltext/plain; charset=utf-849http://repositorio.bc.ufg.br/tede/bitstreams/8e11391d-41b6-43dd-a90e-084521d63320/download4afdbb8c545fd630ea7db775da747b2fMD52license_textlicense_texttext/html; charset=utf-80http://repositorio.bc.ufg.br/tede/bitstreams/d113f30b-71ef-4727-9893-bb18cb42838b/downloadd41d8cd98f00b204e9800998ecf8427eMD53license_rdflicense_rdfapplication/rdf+xml; charset=utf-80http://repositorio.bc.ufg.br/tede/bitstreams/cf8330a0-e617-43b1-bee5-031362ce0412/downloadd41d8cd98f00b204e9800998ecf8427eMD54ORIGINALDissertação - Marco Túlio Lacerda Ribeiro - 2018.pdfDissertação - Marco Túlio Lacerda Ribeiro - 2018.pdfapplication/pdf1380967http://repositorio.bc.ufg.br/tede/bitstreams/799a769c-645f-48bf-b491-d1f08c435f66/download194ed48e2af9c60ef94be3f60db75ef7MD55tede/86682018-07-09 08:27:43.559http://creativecommons.org/licenses/by-nc-nd/4.0/Acesso Abertoopen.accessoai:repositorio.bc.ufg.br:tede/8668http://repositorio.bc.ufg.br/tedeRepositório InstitucionalPUBhttp://repositorio.bc.ufg.br/oai/requesttasesdissertacoes.bc@ufg.bropendoar:2018-07-09T11:27:43Repositório Institucional da UFG - Universidade Federal de Goiás (UFG)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 |
dc.title.eng.fl_str_mv |
Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos |
dc.title.alternative.eng.fl_str_mv |
Effect of chronic treatment with paracetamol on the airway reactivity isolated from rats |
title |
Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos |
spellingShingle |
Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos Ribeiro, Marco Túlio Lacerda Paracetamol Músculo liso Traqueia Asma Estresse oxidativo Paracetamol Smooth muscle Trachea Asthma Oxidative stress FARMACOLOGIA::FARMACOLOGIA GERAL |
title_short |
Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos |
title_full |
Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos |
title_fullStr |
Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos |
title_full_unstemmed |
Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos |
title_sort |
Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos |
author |
Ribeiro, Marco Túlio Lacerda |
author_facet |
Ribeiro, Marco Túlio Lacerda |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Rocha, Matheus Lavorenti |
dc.contributor.advisor1Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4779402Y9 |
dc.contributor.advisor-co1.fl_str_mv |
Castro, Patrícia Ferreira da Silva |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K4217585J1 |
dc.contributor.referee1.fl_str_mv |
Rocha, Matheus Lavorenti |
dc.contributor.referee2.fl_str_mv |
Silva, Vinícius Barreto da |
dc.contributor.referee3.fl_str_mv |
Oliveira, Gisele Augusto Rodrigues de |
dc.contributor.referee4.fl_str_mv |
Santos, Luciano da Ressurreição |
dc.contributor.authorLattes.fl_str_mv |
http://buscatextual.cnpq.br/buscatextual/visualizacv.do?id=K8160397P6 |
dc.contributor.author.fl_str_mv |
Ribeiro, Marco Túlio Lacerda |
contributor_str_mv |
Rocha, Matheus Lavorenti Castro, Patrícia Ferreira da Silva Rocha, Matheus Lavorenti Silva, Vinícius Barreto da Oliveira, Gisele Augusto Rodrigues de Santos, Luciano da Ressurreição |
dc.subject.por.fl_str_mv |
Paracetamol Músculo liso Traqueia Asma Estresse oxidativo |
topic |
Paracetamol Músculo liso Traqueia Asma Estresse oxidativo Paracetamol Smooth muscle Trachea Asthma Oxidative stress FARMACOLOGIA::FARMACOLOGIA GERAL |
dc.subject.eng.fl_str_mv |
Paracetamol Smooth muscle Trachea Asthma Oxidative stress |
dc.subject.cnpq.fl_str_mv |
FARMACOLOGIA::FARMACOLOGIA GERAL |
description |
Background: Some studies relate the use of paracetamol with the exacerbation of asthma symptoms and other respiratory problems. Other studies are inconclusive or deny this correlation. This makes the association between paracetamol and airway hypersensitivity very controversial and still under debate. Objectives: To investigate the effect of chronic treatment with paracetamol on rats on the contraction and relaxation of isolated airways. Methods: Wistar rats were divided into 2 groups (n = 5-8). One group was treated for 2 weeks with paracetamol (400 mg / kg, v.o.) in drinking water and another control group (pure water). The animals were euthanized after two weeks, blood was collected for biochemical analyzes (ALT, AST, TBARs reaction) and tracheal rings were isolated and prepared in an organ bath to measure the isometric tension against contractile stimuli (concentration- effect for carbachol and KCl, concentration- 2+ effect curve for Ca stimulated with carbachol or KCl) and relaxants (isoprenaline, sodium nitroprusside and verapamil). Results: Liver enzymes ALT, AST and lipid peroxidation (TBARs) were significantly increased after paracetamol treatment. Acupuncture of the airway tracheal smooth muscle response does not present any alteration, either to the contractile or relaxing stimulus, for example: cholinergic agonist, membrane 2+ 2+ 2+ depolarization, Ca influx by the sarcolemma, internal release of Ca from the sarcoplasmic reticulum, Ca , β-receptor agonist or NO donor-induced relaxation. Conclusion: Chronic treatment with paracetamol does not induce hyper or hyporeativity of the airways isolated from rats. |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-07-09T11:27:43Z |
dc.date.issued.fl_str_mv |
2018-06-19 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
RIBEIRO, M. T. L. Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos. 2018. 56 f. Dissertação (Mestrado em Ciências Farmacêuticas) - Universidade Federal de Goiás, Goiânia, 2018. |
dc.identifier.uri.fl_str_mv |
http://repositorio.bc.ufg.br/tede/handle/tede/8668 |
identifier_str_mv |
RIBEIRO, M. T. L. Efeito do tratamento crônico com paracetamol sobre a reatividade das vias aéreas isoladas de ratos. 2018. 56 f. Dissertação (Mestrado em Ciências Farmacêuticas) - Universidade Federal de Goiás, Goiânia, 2018. |
url |
http://repositorio.bc.ufg.br/tede/handle/tede/8668 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
824936988196152412 |
dc.relation.confidence.fl_str_mv |
600 600 600 600 |
dc.relation.department.fl_str_mv |
6010281161524209375 |
dc.relation.cnpq.fl_str_mv |
-3959484153940758247 |
dc.relation.sponsorship.fl_str_mv |
2075167498588264571 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.publisher.program.fl_str_mv |
Programa de Pós-graduação em Ciências Farmacêuticas (FF) |
dc.publisher.initials.fl_str_mv |
UFG |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Faculdade Farmácia - FF (RG) |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFG instname:Universidade Federal de Goiás (UFG) instacron:UFG |
instname_str |
Universidade Federal de Goiás (UFG) |
instacron_str |
UFG |
institution |
UFG |
reponame_str |
Repositório Institucional da UFG |
collection |
Repositório Institucional da UFG |
bitstream.url.fl_str_mv |
http://repositorio.bc.ufg.br/tede/bitstreams/a8727cdc-425e-44c7-a6f9-237a8cd24703/download http://repositorio.bc.ufg.br/tede/bitstreams/8e11391d-41b6-43dd-a90e-084521d63320/download http://repositorio.bc.ufg.br/tede/bitstreams/d113f30b-71ef-4727-9893-bb18cb42838b/download http://repositorio.bc.ufg.br/tede/bitstreams/cf8330a0-e617-43b1-bee5-031362ce0412/download http://repositorio.bc.ufg.br/tede/bitstreams/799a769c-645f-48bf-b491-d1f08c435f66/download |
bitstream.checksum.fl_str_mv |
bd3efa91386c1718a7f26a329fdcb468 4afdbb8c545fd630ea7db775da747b2f d41d8cd98f00b204e9800998ecf8427e d41d8cd98f00b204e9800998ecf8427e 194ed48e2af9c60ef94be3f60db75ef7 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFG - Universidade Federal de Goiás (UFG) |
repository.mail.fl_str_mv |
tasesdissertacoes.bc@ufg.br |
_version_ |
1793965491587383296 |