Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil

Detalhes bibliográficos
Autor(a) principal: Popiolski, Tatiane M.
Data de Publicação: 2016
Outros Autores: Otsuka, Issei, Halila, Sami, Muniz, Edvani C., Soldi, Valdir, Borsali, Redouane
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFLA
Texto Completo: http://repositorio.ufla.br/jspui/handle/1/36708
Resumo: Nanoparticles comprised of the poly(ethylene oxide)-b-poly (lactic acid) diblock copolymer (PEO-b-PLA) with and without the incorporation of lavender oil were prepared by nanoprecipitation. Diblock copolymers based on a fixed PEO block (5KDa) and two different PLA segments (4.5 or 10KDa) were used. The morphology, encapsulation efficiency, essential oil-polymer interaction and the release kinetics of the active agent in the nanoparticles, were evaluated. The hydrodynamic radius of the nanoparticles determined by light scattering was affected by the size of the poly(lactic acid) (PLA) block. The lavender essential oil encapsulation efficiency (at a concentration of 0.4 µL mL-1) determined by UV-VIS spectroscopy was in the range of 70-75%. The in vitro release suggests that the polymeric barrier is able to control the oil release.
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spelling Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender OilBlock copolymerNanoparticlesLavender oilCopolímero em blocoNanopartículasÓleo de lavandaNanoparticles comprised of the poly(ethylene oxide)-b-poly (lactic acid) diblock copolymer (PEO-b-PLA) with and without the incorporation of lavender oil were prepared by nanoprecipitation. Diblock copolymers based on a fixed PEO block (5KDa) and two different PLA segments (4.5 or 10KDa) were used. The morphology, encapsulation efficiency, essential oil-polymer interaction and the release kinetics of the active agent in the nanoparticles, were evaluated. The hydrodynamic radius of the nanoparticles determined by light scattering was affected by the size of the poly(lactic acid) (PLA) block. The lavender essential oil encapsulation efficiency (at a concentration of 0.4 µL mL-1) determined by UV-VIS spectroscopy was in the range of 70-75%. The in vitro release suggests that the polymeric barrier is able to control the oil release.Associação Brasileira de Polímeros2019-09-06T13:02:17Z2019-09-06T13:02:17Z2016info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfPROPIOLSKI, T. M. et al. Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil. Materials Research, São Carlos, v. 19, n. 6, p. 1356-1365, 2016.http://repositorio.ufla.br/jspui/handle/1/36708Materials Researchreponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessPopiolski, Tatiane M.Otsuka, IsseiHalila, SamiMuniz, Edvani C.Soldi, ValdirBorsali, Redouaneeng2019-09-06T13:02:17Zoai:localhost:1/36708Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2019-09-06T13:02:17Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false
dc.title.none.fl_str_mv Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
title Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
spellingShingle Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
Popiolski, Tatiane M.
Block copolymer
Nanoparticles
Lavender oil
Copolímero em bloco
Nanopartículas
Óleo de lavanda
title_short Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
title_full Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
title_fullStr Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
title_full_unstemmed Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
title_sort Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil
author Popiolski, Tatiane M.
author_facet Popiolski, Tatiane M.
Otsuka, Issei
Halila, Sami
Muniz, Edvani C.
Soldi, Valdir
Borsali, Redouane
author_role author
author2 Otsuka, Issei
Halila, Sami
Muniz, Edvani C.
Soldi, Valdir
Borsali, Redouane
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Popiolski, Tatiane M.
Otsuka, Issei
Halila, Sami
Muniz, Edvani C.
Soldi, Valdir
Borsali, Redouane
dc.subject.por.fl_str_mv Block copolymer
Nanoparticles
Lavender oil
Copolímero em bloco
Nanopartículas
Óleo de lavanda
topic Block copolymer
Nanoparticles
Lavender oil
Copolímero em bloco
Nanopartículas
Óleo de lavanda
description Nanoparticles comprised of the poly(ethylene oxide)-b-poly (lactic acid) diblock copolymer (PEO-b-PLA) with and without the incorporation of lavender oil were prepared by nanoprecipitation. Diblock copolymers based on a fixed PEO block (5KDa) and two different PLA segments (4.5 or 10KDa) were used. The morphology, encapsulation efficiency, essential oil-polymer interaction and the release kinetics of the active agent in the nanoparticles, were evaluated. The hydrodynamic radius of the nanoparticles determined by light scattering was affected by the size of the poly(lactic acid) (PLA) block. The lavender essential oil encapsulation efficiency (at a concentration of 0.4 µL mL-1) determined by UV-VIS spectroscopy was in the range of 70-75%. The in vitro release suggests that the polymeric barrier is able to control the oil release.
publishDate 2016
dc.date.none.fl_str_mv 2016
2019-09-06T13:02:17Z
2019-09-06T13:02:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv PROPIOLSKI, T. M. et al. Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil. Materials Research, São Carlos, v. 19, n. 6, p. 1356-1365, 2016.
http://repositorio.ufla.br/jspui/handle/1/36708
identifier_str_mv PROPIOLSKI, T. M. et al. Preparation of Polymeric Micelles of Poly (Ethylene Oxide-b-Lactic Acid) and their Encapsulation With Lavender Oil. Materials Research, São Carlos, v. 19, n. 6, p. 1356-1365, 2016.
url http://repositorio.ufla.br/jspui/handle/1/36708
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Polímeros
publisher.none.fl_str_mv Associação Brasileira de Polímeros
dc.source.none.fl_str_mv Materials Research
reponame:Repositório Institucional da UFLA
instname:Universidade Federal de Lavras (UFLA)
instacron:UFLA
instname_str Universidade Federal de Lavras (UFLA)
instacron_str UFLA
institution UFLA
reponame_str Repositório Institucional da UFLA
collection Repositório Institucional da UFLA
repository.name.fl_str_mv Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)
repository.mail.fl_str_mv nivaldo@ufla.br || repositorio.biblioteca@ufla.br
_version_ 1807835051182784512

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