Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl.
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFLA |
Texto Completo: | http://repositorio.ufla.br/jspui/handle/1/48802 |
Resumo: | Protium Burm. f. (Burseraceae) is well known in the Brazilian Amazon for its diversity of species, though some of them are difficult to identify based on only morphological characteristics. We investigated the species Protium puncticulatum J.F. Macbr. and Protium tenuifolium (Engl.) Engl. in relation to their chemical constituents and some biological aspects. The phytochemical study of the hexane extract from the trunk of P. puncticulatum led to the identification of a mixture of triterpenes: α, β-amyrin (1 and 2), and lupeol (3); the methanolic extract gave the lignans 7-oxo-parabenzolactone (4) and 7’-hydroxy-9α-methylcubebin (5); this last lignan showed a MIC of 320 μg/mL for Candida albicans and 160 μg/mL for Cryptococcus neoformans and C. gattii. The hexane extract from the branches of P. tenuifolium also provided a mixture of α and β-amyrin (1, 2); the methanolic extract gave dimeric alkylresorcinols named integracin B (6) and integracin A (7). Analyses of anatomical characteristics confirmed the identity of the species Protium tenuifolium (Engl.) Engl. Essential oils obtained via hydrodistillation from the fresh bark of the trunk of P. tenuifolium showed a predominance of the monoterpenes limonene (56.17%), α-phellandrene (16.22%) and ρ-cymene (10.52%). This study is important since it increases knowledge on the volatile and non-volatile chemical constituents of the woody parts of two species of Protium from the Amazon. |
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Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl.TriterpenesLignansAlkylresorcinols derivativesEssential oilMonoterpenesProtium Burm. f. (Burseraceae) is well known in the Brazilian Amazon for its diversity of species, though some of them are difficult to identify based on only morphological characteristics. We investigated the species Protium puncticulatum J.F. Macbr. and Protium tenuifolium (Engl.) Engl. in relation to their chemical constituents and some biological aspects. The phytochemical study of the hexane extract from the trunk of P. puncticulatum led to the identification of a mixture of triterpenes: α, β-amyrin (1 and 2), and lupeol (3); the methanolic extract gave the lignans 7-oxo-parabenzolactone (4) and 7’-hydroxy-9α-methylcubebin (5); this last lignan showed a MIC of 320 μg/mL for Candida albicans and 160 μg/mL for Cryptococcus neoformans and C. gattii. The hexane extract from the branches of P. tenuifolium also provided a mixture of α and β-amyrin (1, 2); the methanolic extract gave dimeric alkylresorcinols named integracin B (6) and integracin A (7). Analyses of anatomical characteristics confirmed the identity of the species Protium tenuifolium (Engl.) Engl. Essential oils obtained via hydrodistillation from the fresh bark of the trunk of P. tenuifolium showed a predominance of the monoterpenes limonene (56.17%), α-phellandrene (16.22%) and ρ-cymene (10.52%). This study is important since it increases knowledge on the volatile and non-volatile chemical constituents of the woody parts of two species of Protium from the Amazon.International Educative Research Foundation Publisher (IERFP)2022-01-07T15:29:44Z2022-01-07T15:29:44Z2021-05-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfSANTOS, H. C. dos et al. Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. International Journal for Innovation Education and Research, [S.l.], v. 9, n. 5, p. 798-811, May 2021. DOI: 10.31686/ijier.vol9.iss5.3098.http://repositorio.ufla.br/jspui/handle/1/48802International Journal for Innovation Education and Research (IJIER)reponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAAttribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessSantos, Henrique Cativo dosSilva, Samirimi JanuarioNascimento, Claudete CatanhededoFreitas, Jorge Alves deSouza, João Vicente Braga deCortez, Ana Claúdia AlvesFerreira, Antonio GilbertoThomasi, Sérgio ScherrerMarques, Marcia Ortiz MayoFacanali, RoselaineLima, Maria da Pazeng2022-01-07T15:29:44Zoai:localhost:1/48802Repositório InstitucionalPUBhttp://repositorio.ufla.br/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2022-01-07T15:29:44Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)false |
dc.title.none.fl_str_mv |
Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. |
title |
Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. |
spellingShingle |
Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. Santos, Henrique Cativo dos Triterpenes Lignans Alkylresorcinols derivatives Essential oil Monoterpenes |
title_short |
Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. |
title_full |
Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. |
title_fullStr |
Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. |
title_full_unstemmed |
Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. |
title_sort |
Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. |
author |
Santos, Henrique Cativo dos |
author_facet |
Santos, Henrique Cativo dos Silva, Samirimi Januario Nascimento, Claudete Catanhededo Freitas, Jorge Alves de Souza, João Vicente Braga de Cortez, Ana Claúdia Alves Ferreira, Antonio Gilberto Thomasi, Sérgio Scherrer Marques, Marcia Ortiz Mayo Facanali, Roselaine Lima, Maria da Paz |
author_role |
author |
author2 |
Silva, Samirimi Januario Nascimento, Claudete Catanhededo Freitas, Jorge Alves de Souza, João Vicente Braga de Cortez, Ana Claúdia Alves Ferreira, Antonio Gilberto Thomasi, Sérgio Scherrer Marques, Marcia Ortiz Mayo Facanali, Roselaine Lima, Maria da Paz |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Santos, Henrique Cativo dos Silva, Samirimi Januario Nascimento, Claudete Catanhededo Freitas, Jorge Alves de Souza, João Vicente Braga de Cortez, Ana Claúdia Alves Ferreira, Antonio Gilberto Thomasi, Sérgio Scherrer Marques, Marcia Ortiz Mayo Facanali, Roselaine Lima, Maria da Paz |
dc.subject.por.fl_str_mv |
Triterpenes Lignans Alkylresorcinols derivatives Essential oil Monoterpenes |
topic |
Triterpenes Lignans Alkylresorcinols derivatives Essential oil Monoterpenes |
description |
Protium Burm. f. (Burseraceae) is well known in the Brazilian Amazon for its diversity of species, though some of them are difficult to identify based on only morphological characteristics. We investigated the species Protium puncticulatum J.F. Macbr. and Protium tenuifolium (Engl.) Engl. in relation to their chemical constituents and some biological aspects. The phytochemical study of the hexane extract from the trunk of P. puncticulatum led to the identification of a mixture of triterpenes: α, β-amyrin (1 and 2), and lupeol (3); the methanolic extract gave the lignans 7-oxo-parabenzolactone (4) and 7’-hydroxy-9α-methylcubebin (5); this last lignan showed a MIC of 320 μg/mL for Candida albicans and 160 μg/mL for Cryptococcus neoformans and C. gattii. The hexane extract from the branches of P. tenuifolium also provided a mixture of α and β-amyrin (1, 2); the methanolic extract gave dimeric alkylresorcinols named integracin B (6) and integracin A (7). Analyses of anatomical characteristics confirmed the identity of the species Protium tenuifolium (Engl.) Engl. Essential oils obtained via hydrodistillation from the fresh bark of the trunk of P. tenuifolium showed a predominance of the monoterpenes limonene (56.17%), α-phellandrene (16.22%) and ρ-cymene (10.52%). This study is important since it increases knowledge on the volatile and non-volatile chemical constituents of the woody parts of two species of Protium from the Amazon. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-05-01 2022-01-07T15:29:44Z 2022-01-07T15:29:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
SANTOS, H. C. dos et al. Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. International Journal for Innovation Education and Research, [S.l.], v. 9, n. 5, p. 798-811, May 2021. DOI: 10.31686/ijier.vol9.iss5.3098. http://repositorio.ufla.br/jspui/handle/1/48802 |
identifier_str_mv |
SANTOS, H. C. dos et al. Chemical investigation, antifungal activity and anatomical aspects of Protium puncticulatum J.F Macbr. and Protium tenuifolium (Engl.) Engl. International Journal for Innovation Education and Research, [S.l.], v. 9, n. 5, p. 798-811, May 2021. DOI: 10.31686/ijier.vol9.iss5.3098. |
url |
http://repositorio.ufla.br/jspui/handle/1/48802 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial 4.0 International http://creativecommons.org/licenses/by-nc/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
International Educative Research Foundation Publisher (IERFP) |
publisher.none.fl_str_mv |
International Educative Research Foundation Publisher (IERFP) |
dc.source.none.fl_str_mv |
International Journal for Innovation Education and Research (IJIER) reponame:Repositório Institucional da UFLA instname:Universidade Federal de Lavras (UFLA) instacron:UFLA |
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Universidade Federal de Lavras (UFLA) |
instacron_str |
UFLA |
institution |
UFLA |
reponame_str |
Repositório Institucional da UFLA |
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Repositório Institucional da UFLA |
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Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA) |
repository.mail.fl_str_mv |
nivaldo@ufla.br || repositorio.biblioteca@ufla.br |
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1807835202591916032 |