Detalhes bibliográficos
Título da fonte: Repositório Institucional da UFMG
id UFMG_58d9329a0c608aef30dce127a2c969ee
oai_identifier_str oai:repositorio.ufmg.br:1843/52034
network_acronym_str UFMG
network_name_str Repositório Institucional da UFMG
repository_id_str
reponame_str Repositório Institucional da UFMG
instacron_str UFMG
institution Universidade Federal de Minas Gerais (UFMG)
instname_str Universidade Federal de Minas Gerais (UFMG)
spelling 2023-04-14T21:42:41Z2023-04-14T21:42:41Z2020942462512316-5324http://hdl.handle.net/1843/52034https://orcid.org/0000-0003-4713-202Xhttps://orcid.org/0000-0002-9408-2822https://orcid.org/0000-0002-1833-8099https://orcid.org/0000-0003-3193-5469https://orcid.org/0000-0002-3336-9504https://orcid.org/0000-0002-1660-0751Background and objectives: Newborn admitted to neonatal unit are at high risk of acquiring hospital infections and Candida infections are associated with several preventable risk factors. Methods: Paired case-control study was carried out in a neonatal referral unit of a university hospital. Data were collected by trained professionals from the Hospital Infection Control Service. The analysis of risk factors was performed using the Statistical Package for the Social Sciences software. The study was approved by the Ethics Committee. Results: 3,087 admissions and 108 patients were selected (36 cases with Invasive Candidemia and 72 controls). The prevalence of Candidemia was 1.2% and the incidence density was 0.48 per 1000 patients per day. Parenteral nutrition, mechanical ventilation, central venous catheter and use of aminoglycosides showed statistical significance associated with Invasive Candidemia in the univariate analysis. The multivariate analysis showed that newborns who received parenteral nutrition, Odds ratio 3.52 Confidence interval (95%) 1.11-11.16 and urinary catheters Odds ratio 3.91 Confidence interval (95%) 1. 66-9.23 had a higher risk of developing Candidemia. Discussion: Good practices are necessary for the administration of parenteral nutrition and insertion and maintenance of urinary catheters to avoid fungal infections since the risk was greater in neonates who used these devices.Justificativa e objetivos: Recém-nascidos internados em unidade neonatal apresentam alto risco de contrair infecções hospitalares e infecções por Candida estão associadas a vários fatores de risco evitáveis. Métodos: Foi realizado um estudo caso-controle pareado em uma unidade de referência neonatal de um hospital universitário. Os dados foram coletados por profissionais treinados do Serviço de Controle de Infecção Hospitalar. A análise dos fatores de risco foi realizada por meio do software Statistical Package for the Social Sciences. O estudo foi aprovado pelo Comitê de Ética. Resultados: foram selecionados 3.087 internações e 108 pacientes (36 casos com candidemia invasiva e 72 controles). A prevalência de candidemia foi de 1,2% e a densidade de incidência foi de 0,48 por 1000 pacientes por dia. Nutrição parenteral, ventilação mecânica, cateter venoso central e uso de aminoglicosídeos apresentaram significância estatística associada à candidemia invasiva na análise univariada. A análise multivariada mostrou que os recém-nascidos que receberam nutrição parenteral, Odds ratio 3,52 Intervalo de confiança (95%) 1,11-11,16 e odds ratio de cateteres urinários 3,91 Intervalo de confiança (95%) 1,66-9,23 tiveram maior risco de desenvolver Candidemia. Discussão: Boas práticas são necessárias para a administração de nutrição parenteral e a inserção e manutenção de cateter urinário para evitar infecções fúngicas, uma vez que o risco foi maior nos neonatos que utilizaram esses dispositivos.engUniversidade Federal de Minas GeraisUFMGBrasilHCL - HOSPITAL DAS CLINICASMED - DEPARTAMENTO DE PEDIATRIAJournal of Infection ControlInfecções fúngicas invasivasCandidíase invasivaCandidemiaRecém-nascidoFatores de fiscoFungal infectionCandida spp.Invasive candidiasisCandidemiaNeonatesRisk factorsRisk factors for candidemia in newborns in the university reference hospitalFatores de Risco para candidemia em neonatos em um hospital universitário de referênciainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://jic-abih.com.br/index.php/jic/article/view/352Renata Aparecida de SouzaLilian Martins Oliveira DinizLaís Silva CarvalhoLarissa Gonçalves RezendeViviane RosadoJanita FerreiraPaulo Henrique Orlandi MourãoLeni Márcia AnchietaRoberta Maia de Castro Romanelliapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/52034/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALRisk Factors for Candidemia in Newborns in the University Reference Hospital.pdfRisk Factors for Candidemia in Newborns in the University Reference Hospital.pdfapplication/pdf364567https://repositorio.ufmg.br/bitstream/1843/52034/2/Risk%20Factors%20for%20Candidemia%20in%20Newborns%20in%20the%20University%20Reference%20Hospital.pdfe1afc06203200c7b3c4394d4bb9112f8MD521843/520342023-04-14 18:42:41.746oai:repositorio.ufmg.br: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Repositório InstitucionalPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-04-14T21:42:41Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
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