Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes

Detalhes bibliográficos
Autor(a) principal: Lívia Pereira Horta
Data de Publicação: 2016
Outros Autores: Yane Campolina Cachuite Mota, Gisele Maria Barbosa, Taniris Cafiero Braga, Ivanildo Evódio Marriel, Ângelo de Fátima, Luzia Valentina Modolo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFMG
Texto Completo: https://doi.org/10.21577/0103-5053.20160208
http://hdl.handle.net/1843/62178
https://orcid.org/0000-0002-2853-2215
https://orcid.org/0000-0002-4032-0100
https://orcid.org/0000-0002-1670-0285
https://orcid.org/0000-0003-2344-5590
https://orcid.org/0000-0002-8033-0434
Resumo: CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
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spelling 2023-12-26T18:16:05Z2023-12-26T18:16:05Z201627815121519https://doi.org/10.21577/0103-5053.201602081678-4790http://hdl.handle.net/1843/62178https://orcid.org/0000-0002-2853-2215https://orcid.org/0000-0002-4032-0100https://orcid.org/0000-0002-1670-0285https://orcid.org/0000-0003-2344-5590https://orcid.org/0000-0002-8033-0434CNPq - Conselho Nacional de Desenvolvimento Científico e TecnológicoFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas GeraisCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorOutra AgênciaThe plant phenolic natural products (PNPs) protocatechuic aldehyde, syringaldehyde and vanillin were used as platforms for obtaining four urease inhibitors. Urea (urease substrate) or thiourea (urease inhibitor) core was added to the structure of newly synthesized compounds to provide inhibitors up to 230-fold more active than the PNPs they originated from. The PNP derivatives are mixed inhibitors with higher affinity to urease active site. Two compounds were as efficient as N-(butyl)thiophosphoric triamide (NBPT) toward soil. Overall, PNPs derivatives are promising urease inhibitors for use as additive in urea-based fertilizers formulations.engUniversidade Federal de Minas GeraisUFMGBrasilICB - DEPARTAMENTO DE BOTÂNICAICX - DEPARTAMENTO DE QUÍMICAJournal of the Brazilian Chemical SocietyUreia como fertilizanteQuímicaProdutos naturaisFenóisInibidores - UreaseAldeídosUreaUrease inhibitorsNatural productsPhenolic aldehydesFertilizer additiveUrease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://www.scielo.br/j/jbchs/a/yjZC8mqjtfrtj7styVFfXnb/Lívia Pereira HortaYane Campolina Cachuite MotaGisele Maria BarbosaTaniris Cafiero BragaIvanildo Evódio MarrielÂngelo de FátimaLuzia Valentina Modoloapplication/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFMGinstname:Universidade Federal de Minas Gerais (UFMG)instacron:UFMGLICENSELicense.txtLicense.txttext/plain; charset=utf-82042https://repositorio.ufmg.br/bitstream/1843/62178/1/License.txtfa505098d172de0bc8864fc1287ffe22MD51ORIGINALUrease Inhibitors of Agricultural Interest Inspired by Structures of.pdfUrease Inhibitors of Agricultural Interest Inspired by Structures of.pdfapplication/pdf217623https://repositorio.ufmg.br/bitstream/1843/62178/2/Urease%20Inhibitors%20of%20Agricultural%20Interest%20Inspired%20by%20Structures%20of.pdf8590c53f2d3d5ffdd38916b9473df4d3MD521843/621782023-12-26 15:16:05.575oai:repositorio.ufmg.br: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Repositório de PublicaçõesPUBhttps://repositorio.ufmg.br/oaiopendoar:2023-12-26T18:16:05Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)false
dc.title.pt_BR.fl_str_mv Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
title Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
spellingShingle Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
Lívia Pereira Horta
Urea
Urease inhibitors
Natural products
Phenolic aldehydes
Fertilizer additive
Ureia como fertilizante
Química
Produtos naturais
Fenóis
Inibidores - Urease
Aldeídos
title_short Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
title_full Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
title_fullStr Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
title_full_unstemmed Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
title_sort Urease inhibitors of agricultural interest inspired by structures of plant phenolic aldehydes
author Lívia Pereira Horta
author_facet Lívia Pereira Horta
Yane Campolina Cachuite Mota
Gisele Maria Barbosa
Taniris Cafiero Braga
Ivanildo Evódio Marriel
Ângelo de Fátima
Luzia Valentina Modolo
author_role author
author2 Yane Campolina Cachuite Mota
Gisele Maria Barbosa
Taniris Cafiero Braga
Ivanildo Evódio Marriel
Ângelo de Fátima
Luzia Valentina Modolo
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lívia Pereira Horta
Yane Campolina Cachuite Mota
Gisele Maria Barbosa
Taniris Cafiero Braga
Ivanildo Evódio Marriel
Ângelo de Fátima
Luzia Valentina Modolo
dc.subject.por.fl_str_mv Urea
Urease inhibitors
Natural products
Phenolic aldehydes
Fertilizer additive
topic Urea
Urease inhibitors
Natural products
Phenolic aldehydes
Fertilizer additive
Ureia como fertilizante
Química
Produtos naturais
Fenóis
Inibidores - Urease
Aldeídos
dc.subject.other.pt_BR.fl_str_mv Ureia como fertilizante
Química
Produtos naturais
Fenóis
Inibidores - Urease
Aldeídos
description CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2023-12-26T18:16:05Z
dc.date.available.fl_str_mv 2023-12-26T18:16:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1843/62178
dc.identifier.doi.pt_BR.fl_str_mv https://doi.org/10.21577/0103-5053.20160208
dc.identifier.issn.pt_BR.fl_str_mv 1678-4790
dc.identifier.orcid.pt_BR.fl_str_mv https://orcid.org/0000-0002-2853-2215
https://orcid.org/0000-0002-4032-0100
https://orcid.org/0000-0002-1670-0285
https://orcid.org/0000-0003-2344-5590
https://orcid.org/0000-0002-8033-0434
url https://doi.org/10.21577/0103-5053.20160208
http://hdl.handle.net/1843/62178
https://orcid.org/0000-0002-2853-2215
https://orcid.org/0000-0002-4032-0100
https://orcid.org/0000-0002-1670-0285
https://orcid.org/0000-0003-2344-5590
https://orcid.org/0000-0002-8033-0434
identifier_str_mv 1678-4790
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Journal of the Brazilian Chemical Society
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.publisher.initials.fl_str_mv UFMG
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv ICB - DEPARTAMENTO DE BOTÂNICA
ICX - DEPARTAMENTO DE QUÍMICA
publisher.none.fl_str_mv Universidade Federal de Minas Gerais
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFMG
instname:Universidade Federal de Minas Gerais (UFMG)
instacron:UFMG
instname_str Universidade Federal de Minas Gerais (UFMG)
instacron_str UFMG
institution UFMG
reponame_str Repositório Institucional da UFMG
collection Repositório Institucional da UFMG
bitstream.url.fl_str_mv https://repositorio.ufmg.br/bitstream/1843/62178/1/License.txt
https://repositorio.ufmg.br/bitstream/1843/62178/2/Urease%20Inhibitors%20of%20Agricultural%20Interest%20Inspired%20by%20Structures%20of.pdf
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repository.name.fl_str_mv Repositório Institucional da UFMG - Universidade Federal de Minas Gerais (UFMG)
repository.mail.fl_str_mv
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