CXCL-16, IL-17, and bone morphogenetic protein 2 (BMP-2) are associated with overweight and obesity conditions in middle-aged and elderly women.

• Autor(a) principal: Ribeiro, Silvana Mara Luz Turbino
• Data de Publicação: 2017
• Outros Autores: Lopes, Laís Roquete, Costa, Guilherme de Paula, Figueiredo, Vivian Paulino, Bajracharya, Deena Shrestha, Batista, Aline Priscila, Nicolato, Roney Luiz de Carvalho, Oliveira, Fernando Luiz Pereira de, Estanislau, Juliana de Assis Silva Gomes, Silva, André Talvani Pedrosa da
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFOP
• Texto Completo: http://www.repositorio.ufop.br/handle/123456789/9387; https://doi.org/10.1186/s12979-017-0089-0
• topic: Inflammation; Elderly; Overweight; Obesity

The current concept of overweight/obesity is most likely related to a combination of increased caloric intake and decreased energy expenditure. Widespread inflammation, associated with both conditions, appears to contribute to the development of some obesity-related comorbidities. Interventions that directly or indirectly target individuals at high risk of developing obesity have been largely proposed because of the increasing number of overweight/obese cases worldwide. The aim of the present study was to assess CXCL16, IL-17, and BMP-2 plasma factors in middle-aged and elderly women and relate them to an overweight or obese status. In total, 117 women were selected and grouped as eutrophic, overweight, and obese, according to anthropometric parameters. Analyses of anthropometric and circulating biochemical parameters were followed by plasma immunoassays for CXCL-16, IL- 17, and BMP-2.