PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Clinical and Biomedical Research |
Texto Completo: | https://seer.ufrgs.br/index.php/hcpa/article/view/126194 |
Resumo: | Background: Type 2 diabetes (DM2) has been related to development of macroangiopatic [coronary heart disease (CHD), peripheral vascular disease (PVD) and stroke] and microangiopatic complications [retinopathy, nefropathy, and distal sensory neuropathy (DSN)]. The aims of this study were to analyze the prevalence of complications in DM2 patients and to estimate their associated risk factors. Methods: Cross-sectional study, including 927 patients with DM2 (42% males, meanage: 59 ± 10 years; mean known duration of DM2: 12 ± 8 years). Retinopathy was identified by direct fundoscopy; CHD by WHO questionnaire and/or abnormal ECG and/or perfusion abnormalities on myocardial scintigraphy; DSN by compatible symptoms and absent sensation on 10 g monofilament and/or tune fork; PVD by the presence of claudication and absent foot pulses, stroke by presence of sequels and history, and nephropathy by urinary albumin excretion rate (³ 20 mg/min). Hypertension was defined by blood pressure (³ 140/90 mmhg) and/or use of antihypertensive drugs. Body mass index (BMI, kg/m2 ) and waist-to-hip ratio (WHR) were calculated. Results: CHD was present in 36% and PVD in 33%. Among microvascular, 37% had nefropathy (12% with macroalbuminuria); 46% retinopathy (15% proliferative retinopathy). DSN was present in 36%. Seventy three percent of the patients presented arterial hypertension. Cholesterol levels were >200 mg/dl in 64% and BMI > 30 kg/m2 in 36%. Twenty two percent of patients were smokers and 21% ex-smokers. Conclusion: Diabetic complications are frequent among out patients attending to general hospitals. Almost all patients presented at least one risk factor for cardiovascular disease, what valid the efforts to their identification and adequate control. |
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Clinical and Biomedical Research |
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PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CAREPREVALÊNCIA DE COMPLICAÇÕES MICRO- E MACROVASCULARES E DE SEUS FATORES DE RISCO EM PACIENTES COM DIABETES MELITO DO TIPO 2 EM ATENDIMENTO AMBULATORIALdiabetes melitocomplicações crônicasfatores de risco: diabetes mellituschronic complicationsrisk factorsBackground: Type 2 diabetes (DM2) has been related to development of macroangiopatic [coronary heart disease (CHD), peripheral vascular disease (PVD) and stroke] and microangiopatic complications [retinopathy, nefropathy, and distal sensory neuropathy (DSN)]. The aims of this study were to analyze the prevalence of complications in DM2 patients and to estimate their associated risk factors. Methods: Cross-sectional study, including 927 patients with DM2 (42% males, meanage: 59 ± 10 years; mean known duration of DM2: 12 ± 8 years). Retinopathy was identified by direct fundoscopy; CHD by WHO questionnaire and/or abnormal ECG and/or perfusion abnormalities on myocardial scintigraphy; DSN by compatible symptoms and absent sensation on 10 g monofilament and/or tune fork; PVD by the presence of claudication and absent foot pulses, stroke by presence of sequels and history, and nephropathy by urinary albumin excretion rate (³ 20 mg/min). Hypertension was defined by blood pressure (³ 140/90 mmhg) and/or use of antihypertensive drugs. Body mass index (BMI, kg/m2 ) and waist-to-hip ratio (WHR) were calculated. Results: CHD was present in 36% and PVD in 33%. Among microvascular, 37% had nefropathy (12% with macroalbuminuria); 46% retinopathy (15% proliferative retinopathy). DSN was present in 36%. Seventy three percent of the patients presented arterial hypertension. Cholesterol levels were >200 mg/dl in 64% and BMI > 30 kg/m2 in 36%. Twenty two percent of patients were smokers and 21% ex-smokers. Conclusion: Diabetic complications are frequent among out patients attending to general hospitals. Almost all patients presented at least one risk factor for cardiovascular disease, what valid the efforts to their identification and adequate control. Objetivos: O diabetes melito (DM) do tipo 2 está associado ao desenvolvimento de complicações macroangiopáticas [cardiopatia isquêmica (CI), doença vascular periférica (DVP) e acidente vascular cerebral (AVC)] e microangiopáticas [retinopatia diabética (RD), nefropatia diabética (ND) e neuropatia sensitiva distal (NSD)]. Os objetivos deste estudo foram avaliar a prevalência das complicações crônicas em pacientes com DM do tipo 2 e aferir os seus possíveis fatores de risco. Métodos: Estudo transversal, incluindo 927 pacientes com DM do tipo 2 (42% homens, média de idade: 59 ± 10 anos; duração média do DM do tipo 2: 12 ± 8 anos). A RD foi definida por fundoscopia direta; a CI através do questionário da OMS e/ou alterações eletrocardiográficas e/ou anormalidades perfusionais na cintilografia miocárdica; a NSD por sintomas compatíveis e ausência de sensação ao monofilamento de 10g e/ou ao diapasão; a DVP pela claudicação e ausência de pulsos pediosos; o AVC por seqüelas ou história compatível e a ND pela excreção urinária de albumina (≥ 20 µg/min). A hipertensão arterial sistêmica (HAS) foi definidapelos níveis pressóricos (≥ 140/90 mmHg) e/ou uso de drogas anti-hipertensivas. Foram calculados o índice de massa corporal (IMC, kg/m2 ) e a razão cintura-quadril (RCQ). Resultados: A CI estava presente em 36% e a DVP em 33% dos pacientes. Dentre as complicações microvasculares, 37% tinham doença renal (12% macroalbuminúricos) e 46% RD (15% retinopatia proliferativa). A NSD foi encontrada em 36% dos pacientes. HAS estava presente em 73% dos pacientes. O colesterol estava acima de 200 mg/dl em 64%, enquanto o IMC > 30 kg/m2 em 36%. Vinte e dois por cento dos pacientes eram fumantes atuais e 21% ex-tabagistas. Conclusão: As complicações crônicas do DM do 2 têm uma alta prevalência nos pacientes ambulatoriais de hospitais gerais. Praticamente todos os pacientes apresentavam pelo menos um fator de risco para doença cardiovascular, o que justifica o seu rastreamento e controle. Unitermos: diabetes melito, complicações crônicas, fatores de risco.HCPA/FAMED/UFRGS2022-09-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/126194Clinical & Biomedical Research; Vol. 23 No. 1 - 2 (2003): Revista HCPAClinical and Biomedical Research; v. 23 n. 1 - 2 (2003): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/126194/85679Copyright (c) 2022 Rafael Selbach Scheffel, Desirê Bortolanza, Cristiane Seganfredo Weber, Dra. Luciana Abarno da Costa, Dr. Luís Henrique Canani, Kátia Gonçalves dos Santos, Daisy Crispim, Dr. Israel Roisenberg, Dr. Hugo Roberto Kurtz Lisbôa, Dra. Glaucia Sarturi Tres, Dr. Balduíno Tschiedel, Dr. Jorge Luiz Grosshttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSelbach Scheffel, Rafael Bortolanza, Desirê Seganfredo Weber, Cristiane Abarno da Costa, Luciana Canani, Luís HenriqueGonçalves dos Santos, Kátia Crispim, Daisy Roisenberg, IsraelKurtz Lisbôa, Hugo Roberto Sarturi Tres, Glaucia Tschiedel, Balduíno Gross, Jorge Luiz2022-09-27T20:38:15Zoai:seer.ufrgs.br:article/126194Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-09-27T20:38:15Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.none.fl_str_mv |
PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE PREVALÊNCIA DE COMPLICAÇÕES MICRO- E MACROVASCULARES E DE SEUS FATORES DE RISCO EM PACIENTES COM DIABETES MELITO DO TIPO 2 EM ATENDIMENTO AMBULATORIAL |
title |
PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE |
spellingShingle |
PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE Selbach Scheffel, Rafael diabetes melito complicações crônicas fatores de risco : diabetes mellitus chronic complications risk factors |
title_short |
PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE |
title_full |
PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE |
title_fullStr |
PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE |
title_full_unstemmed |
PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE |
title_sort |
PREVALENCE OF MICRO- AND MACROANGIOPATHIC CHRONIC COMPLICATIONS AND THEIR RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS IN AMBULATORY CARE |
author |
Selbach Scheffel, Rafael |
author_facet |
Selbach Scheffel, Rafael Bortolanza, Desirê Seganfredo Weber, Cristiane Abarno da Costa, Luciana Canani, Luís Henrique Gonçalves dos Santos, Kátia Crispim, Daisy Roisenberg, Israel Kurtz Lisbôa, Hugo Roberto Sarturi Tres, Glaucia Tschiedel, Balduíno Gross, Jorge Luiz |
author_role |
author |
author2 |
Bortolanza, Desirê Seganfredo Weber, Cristiane Abarno da Costa, Luciana Canani, Luís Henrique Gonçalves dos Santos, Kátia Crispim, Daisy Roisenberg, Israel Kurtz Lisbôa, Hugo Roberto Sarturi Tres, Glaucia Tschiedel, Balduíno Gross, Jorge Luiz |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Selbach Scheffel, Rafael Bortolanza, Desirê Seganfredo Weber, Cristiane Abarno da Costa, Luciana Canani, Luís Henrique Gonçalves dos Santos, Kátia Crispim, Daisy Roisenberg, Israel Kurtz Lisbôa, Hugo Roberto Sarturi Tres, Glaucia Tschiedel, Balduíno Gross, Jorge Luiz |
dc.subject.por.fl_str_mv |
diabetes melito complicações crônicas fatores de risco : diabetes mellitus chronic complications risk factors |
topic |
diabetes melito complicações crônicas fatores de risco : diabetes mellitus chronic complications risk factors |
description |
Background: Type 2 diabetes (DM2) has been related to development of macroangiopatic [coronary heart disease (CHD), peripheral vascular disease (PVD) and stroke] and microangiopatic complications [retinopathy, nefropathy, and distal sensory neuropathy (DSN)]. The aims of this study were to analyze the prevalence of complications in DM2 patients and to estimate their associated risk factors. Methods: Cross-sectional study, including 927 patients with DM2 (42% males, meanage: 59 ± 10 years; mean known duration of DM2: 12 ± 8 years). Retinopathy was identified by direct fundoscopy; CHD by WHO questionnaire and/or abnormal ECG and/or perfusion abnormalities on myocardial scintigraphy; DSN by compatible symptoms and absent sensation on 10 g monofilament and/or tune fork; PVD by the presence of claudication and absent foot pulses, stroke by presence of sequels and history, and nephropathy by urinary albumin excretion rate (³ 20 mg/min). Hypertension was defined by blood pressure (³ 140/90 mmhg) and/or use of antihypertensive drugs. Body mass index (BMI, kg/m2 ) and waist-to-hip ratio (WHR) were calculated. Results: CHD was present in 36% and PVD in 33%. Among microvascular, 37% had nefropathy (12% with macroalbuminuria); 46% retinopathy (15% proliferative retinopathy). DSN was present in 36%. Seventy three percent of the patients presented arterial hypertension. Cholesterol levels were >200 mg/dl in 64% and BMI > 30 kg/m2 in 36%. Twenty two percent of patients were smokers and 21% ex-smokers. Conclusion: Diabetic complications are frequent among out patients attending to general hospitals. Almost all patients presented at least one risk factor for cardiovascular disease, what valid the efforts to their identification and adequate control. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-09-23 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article Avaliado por Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/126194 |
url |
https://seer.ufrgs.br/index.php/hcpa/article/view/126194 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/126194/85679 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
dc.source.none.fl_str_mv |
Clinical & Biomedical Research; Vol. 23 No. 1 - 2 (2003): Revista HCPA Clinical and Biomedical Research; v. 23 n. 1 - 2 (2003): Revista HCPA 2357-9730 reponame:Clinical and Biomedical Research instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Clinical and Biomedical Research |
collection |
Clinical and Biomedical Research |
repository.name.fl_str_mv |
Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
||cbr@hcpa.edu.br |
_version_ |
1799767057541103616 |