Exercise-induced bronchospasm in children

• Autor(a) principal: C. Marostica, Paulo José
• Data de Publicação: 2022
• Outros Autores: R. Silva, Alexandre, S. Souza, André Henrique, Traiber, Cristiane, O. Fonseca, Deisi Letícia, Werner, Juliana, A.P. Machado, Maria Mônica
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Clinical and Biomedical Research
• Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/125267
• topic: Asma; hiperatividade brônquica; crianças; broncoconstrição; atividade física; Asthma; bronchial hyperreactivity; children; airway constriction; physical activity

We review the concept, pathophysiology, clinical diagnosis, pulmonary function tests, and treatment of exercise-induced bronchospasm in children. Exercise-induced bronchospasm is the acute narrowing of the airway that is triggered by vigorous physical activity in individuals with airway hyperreactivity. It is characterized by several degrees of obstruction occurring some minutes after the end of exercise. A late responsemay also occur, usually in children. Exercise-induced bronchospasm in children affects up to 15% of general population, and it is more prevalent in asthmatics. Diagnosis is suggested by typical history, and confirmed by specific tests. The clinical presentation is variable. Its diagnosis is confirmed by a recorded fall in the peak expiratory flow (PEF) or forced expiratory volume in 1 second (FEV1 ) of 15% or higher after exercise, or by a decrease in the forced expiratory flow at 25-75% (FEF25-75) of 20% in relation to baseline measurements. Many theories try to explain the pathophysiology of this condition. Beta-2 agonists are the most common drugs used in the treatment of exerciseinduced bronchospasm and in prophylaxis. Mast cell stabilizing agents and leukotriene antagonists can also be used. Exercise-induced bronchospasm should be remembered in asthmatic patients that present symptoms on exercising. Although there is a large amount of informationavailable about therapeutic options, there is still much to be explored in this field of study