Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner

Detalhes bibliográficos
Autor(a) principal: Giacomini, Ana Cristina Vendrametto Varrone
Data de Publicação: 2016
Outros Autores: Abreu, Murilo Sander de, Zanandrea, Rodrigo, Saibt, Nathália, Friedrich, Maria Tereza, Koakoski, Gessi, Gusso, Darlan, Piato, Angelo Luis Stapassoli, Barcellos, Leonardo Jose Gil
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/225561
Resumo: Here we provide evidence that both pharmacological and environmental manipulations similarly blunt the cortisol release in response to an acute stressor in adult zebrafish. Different groups of fish were maintained isolated or group-housed in barren or enriched tanks, and then exposed or not to diazepam or fluoxetine. Acute stress increased cortisol levels in group-housed zebrafish maintained in barren environment. Single-housed zebrafish displayed a blunted cortisol response to stress. Environmental enrichment also blunted the stress response and this was observed in both isolated and group-housed fish. The same blunting effect was observed in zebrafish exposed to diazepam or fluoxetine. We highlighted environmental enrichment as an alternative and/or complimentary therapeutic for reducing stress and as a promoter of animal welfare.
id UFRGS-2_61b794ac1e521e315025a43e8713981a
oai_identifier_str oai:www.lume.ufrgs.br:10183/225561
network_acronym_str UFRGS-2
network_name_str Repositório Institucional da UFRGS
repository_id_str
spelling Giacomini, Ana Cristina Vendrametto VarroneAbreu, Murilo Sander deZanandrea, RodrigoSaibt, NatháliaFriedrich, Maria TerezaKoakoski, GessiGusso, DarlanPiato, Angelo Luis StapassoliBarcellos, Leonardo Jose Gil2021-08-11T04:48:49Z20162045-2322http://hdl.handle.net/10183/225561001006707Here we provide evidence that both pharmacological and environmental manipulations similarly blunt the cortisol release in response to an acute stressor in adult zebrafish. Different groups of fish were maintained isolated or group-housed in barren or enriched tanks, and then exposed or not to diazepam or fluoxetine. Acute stress increased cortisol levels in group-housed zebrafish maintained in barren environment. Single-housed zebrafish displayed a blunted cortisol response to stress. Environmental enrichment also blunted the stress response and this was observed in both isolated and group-housed fish. The same blunting effect was observed in zebrafish exposed to diazepam or fluoxetine. We highlighted environmental enrichment as an alternative and/or complimentary therapeutic for reducing stress and as a promoter of animal welfare.application/pdfengScientific reports. London. Vol. 6 (2016), article 28986, 6 p.Estresse psicológicoPsicotrópicosPeixe-zebraAnimal physiologyStress and resilienceEnvironmental and pharmacological manipulations blunt the stress response of zebrafish in a similar mannerEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001006707.pdf.txt001006707.pdf.txtExtracted Texttext/plain25673http://www.lume.ufrgs.br/bitstream/10183/225561/2/001006707.pdf.txt3abe571ba93478518336718c92b4db04MD52ORIGINAL001006707.pdfTexto completo (inglês)application/pdf1126503http://www.lume.ufrgs.br/bitstream/10183/225561/1/001006707.pdffb342d5edb64b001aa032b3523ac6864MD5110183/2255612024-05-01 06:51:52.250698oai:www.lume.ufrgs.br:10183/225561Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2024-05-01T09:51:52Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner
title Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner
spellingShingle Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner
Giacomini, Ana Cristina Vendrametto Varrone
Estresse psicológico
Psicotrópicos
Peixe-zebra
Animal physiology
Stress and resilience
title_short Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner
title_full Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner
title_fullStr Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner
title_full_unstemmed Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner
title_sort Environmental and pharmacological manipulations blunt the stress response of zebrafish in a similar manner
author Giacomini, Ana Cristina Vendrametto Varrone
author_facet Giacomini, Ana Cristina Vendrametto Varrone
Abreu, Murilo Sander de
Zanandrea, Rodrigo
Saibt, Nathália
Friedrich, Maria Tereza
Koakoski, Gessi
Gusso, Darlan
Piato, Angelo Luis Stapassoli
Barcellos, Leonardo Jose Gil
author_role author
author2 Abreu, Murilo Sander de
Zanandrea, Rodrigo
Saibt, Nathália
Friedrich, Maria Tereza
Koakoski, Gessi
Gusso, Darlan
Piato, Angelo Luis Stapassoli
Barcellos, Leonardo Jose Gil
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Giacomini, Ana Cristina Vendrametto Varrone
Abreu, Murilo Sander de
Zanandrea, Rodrigo
Saibt, Nathália
Friedrich, Maria Tereza
Koakoski, Gessi
Gusso, Darlan
Piato, Angelo Luis Stapassoli
Barcellos, Leonardo Jose Gil
dc.subject.por.fl_str_mv Estresse psicológico
Psicotrópicos
Peixe-zebra
topic Estresse psicológico
Psicotrópicos
Peixe-zebra
Animal physiology
Stress and resilience
dc.subject.eng.fl_str_mv Animal physiology
Stress and resilience
description Here we provide evidence that both pharmacological and environmental manipulations similarly blunt the cortisol release in response to an acute stressor in adult zebrafish. Different groups of fish were maintained isolated or group-housed in barren or enriched tanks, and then exposed or not to diazepam or fluoxetine. Acute stress increased cortisol levels in group-housed zebrafish maintained in barren environment. Single-housed zebrafish displayed a blunted cortisol response to stress. Environmental enrichment also blunted the stress response and this was observed in both isolated and group-housed fish. The same blunting effect was observed in zebrafish exposed to diazepam or fluoxetine. We highlighted environmental enrichment as an alternative and/or complimentary therapeutic for reducing stress and as a promoter of animal welfare.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2021-08-11T04:48:49Z
dc.type.driver.fl_str_mv Estrangeiro
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/225561
dc.identifier.issn.pt_BR.fl_str_mv 2045-2322
dc.identifier.nrb.pt_BR.fl_str_mv 001006707
identifier_str_mv 2045-2322
001006707
url http://hdl.handle.net/10183/225561
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Scientific reports. London. Vol. 6 (2016), article 28986, 6 p.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
bitstream.url.fl_str_mv http://www.lume.ufrgs.br/bitstream/10183/225561/2/001006707.pdf.txt
http://www.lume.ufrgs.br/bitstream/10183/225561/1/001006707.pdf
bitstream.checksum.fl_str_mv 3abe571ba93478518336718c92b4db04
fb342d5edb64b001aa032b3523ac6864
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv
_version_ 1801225032137965568

Registros relacionados