Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/112031 |
Resumo: | The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer’s recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1 , respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating, pregnancy and lactation. The total number of spermatozoa, their daily production sperm morphology, histopathology and weight of sexual organs were evaluated. The results showed the interference of the phytotherapic formulations A and B in the total number of spermatozoa and in the sperm morphology in a dose-dependent manner. |
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Hollenbach, Clarissa BoemlerBortolini, Carlos EduardoRodrigues, Juliano MattosHirtz, LucasMello, Fernanda Bastos deMello, Joao Roberto Braga de2015-03-13T01:59:00Z20122224-4700http://hdl.handle.net/10183/112031000930764The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer’s recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1 , respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating, pregnancy and lactation. The total number of spermatozoa, their daily production sperm morphology, histopathology and weight of sexual organs were evaluated. The results showed the interference of the phytotherapic formulations A and B in the total number of spermatozoa and in the sperm morphology in a dose-dependent manner.El presente estudio evalúa los efectos de dos formulaciones comerciales que contienen fitoterapéuticos Glycine max (L.) Merr. (Soja) (fitoterapéutico A y fitoterapéutico B) sobre la fertilidad de ratas Wistar. Las dosis se basaron en las recomendaciones del fabricante y el aumento en una escala logarítmica. Los animales se dividieron en seis grupos experimentales y un grupo control, que recibió agua destilada. Tres grupos fueron tratados con un fitoterapéutico y tres grupos fueron tratados con fitoterapéutico B. Las dosis fueron: 4.3mg.kg-1.day-1, 21,5 mg.kg-1.day-1 y 43 mg.kg-1.day-1 , respectivamente, para GPA1, GPA2, GPA3 y GPB1, GPB2, GPB3. Los machos fueron tratados durante noventa y un días, antes y durante el apareamiento. Las Hembras Wistar fueron tratadas antes y durante el apareamiento, el embarazo y la lactancia. Número total de espermatozoides, la producción diaria de espermatozoides, la morfología del esperma, la histopatología y el peso de los órganos sexuales fueron evaluados. Los resultados mostraron la interferencia de las formulaciones fitoterapéuticos A y B en el número total de espermatozoides y en la morfología de los espermatozoides de una manera dosis-dependiente.application/pdfengRevista de salud animal. Mayabeque, Cuba. Vol. 31, no. 1 (ene./abr. 2012), p. 31-39Feijão de sojaFertilidadeMedicamentos fitoterápicos : ToxicidadeRatosSoyGlycine maxPhytotherapicMale ratsFertilityToxicitySojaFitoterapéuticosRatas machosFertilidadToxicidadEffects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertilityEfectos de dos formulaciones fitoterapéuticas que contienen Glycine max (L.) Merr sobre la fertilidad de ratas machos Estrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000930764.pdf000930764.pdfTexto completo (inglês)application/pdf138757http://www.lume.ufrgs.br/bitstream/10183/112031/1/000930764.pdf04a9f8a42c7875ec6da064d9c98772f6MD51TEXT000930764.pdf.txt000930764.pdf.txtExtracted Texttext/plain29997http://www.lume.ufrgs.br/bitstream/10183/112031/2/000930764.pdf.txt333a4007db2a7e975b7db08c2166f1beMD52THUMBNAIL000930764.pdf.jpg000930764.pdf.jpgGenerated Thumbnailimage/jpeg2129http://www.lume.ufrgs.br/bitstream/10183/112031/3/000930764.pdf.jpg981a74c47a2725be2c945b61032a7653MD5310183/1120312021-03-09 04:28:45.04545oai:www.lume.ufrgs.br:10183/112031Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-03-09T07:28:45Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility |
dc.title.alternative.es.fl_str_mv |
Efectos de dos formulaciones fitoterapéuticas que contienen Glycine max (L.) Merr sobre la fertilidad de ratas machos |
title |
Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility |
spellingShingle |
Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility Hollenbach, Clarissa Boemler Feijão de soja Fertilidade Medicamentos fitoterápicos : Toxicidade Ratos Soy Glycine max Phytotherapic Male rats Fertility Toxicity Soja Fitoterapéuticos Ratas machos Fertilidad Toxicidad |
title_short |
Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility |
title_full |
Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility |
title_fullStr |
Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility |
title_full_unstemmed |
Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility |
title_sort |
Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility |
author |
Hollenbach, Clarissa Boemler |
author_facet |
Hollenbach, Clarissa Boemler Bortolini, Carlos Eduardo Rodrigues, Juliano Mattos Hirtz, Lucas Mello, Fernanda Bastos de Mello, Joao Roberto Braga de |
author_role |
author |
author2 |
Bortolini, Carlos Eduardo Rodrigues, Juliano Mattos Hirtz, Lucas Mello, Fernanda Bastos de Mello, Joao Roberto Braga de |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Hollenbach, Clarissa Boemler Bortolini, Carlos Eduardo Rodrigues, Juliano Mattos Hirtz, Lucas Mello, Fernanda Bastos de Mello, Joao Roberto Braga de |
dc.subject.por.fl_str_mv |
Feijão de soja Fertilidade Medicamentos fitoterápicos : Toxicidade Ratos |
topic |
Feijão de soja Fertilidade Medicamentos fitoterápicos : Toxicidade Ratos Soy Glycine max Phytotherapic Male rats Fertility Toxicity Soja Fitoterapéuticos Ratas machos Fertilidad Toxicidad |
dc.subject.eng.fl_str_mv |
Soy Glycine max Phytotherapic Male rats Fertility Toxicity |
dc.subject.spa.fl_str_mv |
Soja Fitoterapéuticos Ratas machos Fertilidad Toxicidad |
description |
The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer’s recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1 , respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating, pregnancy and lactation. The total number of spermatozoa, their daily production sperm morphology, histopathology and weight of sexual organs were evaluated. The results showed the interference of the phytotherapic formulations A and B in the total number of spermatozoa and in the sperm morphology in a dose-dependent manner. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2015-03-13T01:59:00Z |
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Estrangeiro info:eu-repo/semantics/article |
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http://hdl.handle.net/10183/112031 |
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2224-4700 |
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000930764 |
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http://hdl.handle.net/10183/112031 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Revista de salud animal. Mayabeque, Cuba. Vol. 31, no. 1 (ene./abr. 2012), p. 31-39 |
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openAccess |
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