Increase in Hippocampal Theta Oscillations during Spatial Decision Making
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/jspui/handle/1/11785 |
Resumo: | The processing of spatial and mnemonic information is believed to depend on hippocampal theta oscillations (5–12 Hz). However, in rats both the power and the frequency of the theta rhythm are modulated by locomotor activity, which is a major confounding factor when estimating its cognitive correlates. Previous studies have suggested that hippocampal theta oscillations support decision-making processes. In this study, we investigated to what extent spatial decision making modulates hippocampal theta oscillations when controlling for variations in locomotion speed. We recorded local field potentials from the CA1 region of rats while animals had to choose one arm to enter for reward (goal) in a four-arm radial maze. We observed prominent theta oscillations during the decision-making period of the task, which occurred in the center of the maze before animals deliberately ran through an arm toward goal location. In speed-controlled analyses, theta power and frequency were higher during the decision period when compared to either an intertrial delay period (also at the maze center), or to the period of running toward goal location. In addition, theta activity was higher during decision periods preceding correct choices than during decision periods preceding incorrect choices. Altogether, our data support a cognitive function for the hippocampal theta rhythm in spatial decision making |
id |
UFRN_0fd45b870a654cb7286a14d1edd3a0cd |
---|---|
oai_identifier_str |
oai:https://repositorio.ufrn.br:1/11785 |
network_acronym_str |
UFRN |
network_name_str |
Repositório Institucional da UFRN |
repository_id_str |
|
spelling |
Belchior, HindiaelLopes-dos-Santos, VitorTort, Adriano Bretanha LopesRibeiro, Sidarta Tollendal Gomes2014-03-13T16:16:48Z2014-03-13T16:16:48Z2014-02BELCHIOR, Hindiael et. al. Increase in Hippocampal Theta Oscillations during Spatial Decision Making. Hippocampus, fev., 2014.1050-9631https://repositorio.ufrn.br/jspui/handle/1/11785The processing of spatial and mnemonic information is believed to depend on hippocampal theta oscillations (5–12 Hz). However, in rats both the power and the frequency of the theta rhythm are modulated by locomotor activity, which is a major confounding factor when estimating its cognitive correlates. Previous studies have suggested that hippocampal theta oscillations support decision-making processes. In this study, we investigated to what extent spatial decision making modulates hippocampal theta oscillations when controlling for variations in locomotion speed. We recorded local field potentials from the CA1 region of rats while animals had to choose one arm to enter for reward (goal) in a four-arm radial maze. We observed prominent theta oscillations during the decision-making period of the task, which occurred in the center of the maze before animals deliberately ran through an arm toward goal location. In speed-controlled analyses, theta power and frequency were higher during the decision period when compared to either an intertrial delay period (also at the maze center), or to the period of running toward goal location. In addition, theta activity was higher during decision periods preceding correct choices than during decision periods preceding incorrect choices. Altogether, our data support a cognitive function for the hippocampal theta rhythm in spatial decision makingengLFPoscillationsspatial choicelocomotionradial mazeIncrease in Hippocampal Theta Oscillations during Spatial Decision Makinginfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALRibeiro_Increase_in_hippocampal_theta.pdfRibeiro_Increase_in_hippocampal_theta.pdfapplication/pdf879516https://repositorio.ufrn.br/bitstream/1/11785/1/Ribeiro_Increase_in_hippocampal_theta.pdf87e5057d139c9d67d8905c5da27ae4efMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://repositorio.ufrn.br/bitstream/1/11785/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTRibeiro_Increase_in_hippocampal_theta.pdf.txtRibeiro_Increase_in_hippocampal_theta.pdf.txtExtracted texttext/plain46233https://repositorio.ufrn.br/bitstream/1/11785/7/Ribeiro_Increase_in_hippocampal_theta.pdf.txt6d0812b2668e698fb589116eecc06205MD57THUMBNAILRibeiro_Increase_in_hippocampal_theta.pdf.jpgRibeiro_Increase_in_hippocampal_theta.pdf.jpgIM Thumbnailimage/jpeg9552https://repositorio.ufrn.br/bitstream/1/11785/8/Ribeiro_Increase_in_hippocampal_theta.pdf.jpg7c0bc82b67e8fc19b23c3b41841faef3MD581/117852021-07-10 19:06:05.754oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-07-10T22:06:05Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Increase in Hippocampal Theta Oscillations during Spatial Decision Making |
title |
Increase in Hippocampal Theta Oscillations during Spatial Decision Making |
spellingShingle |
Increase in Hippocampal Theta Oscillations during Spatial Decision Making Belchior, Hindiael LFP oscillations spatial choice locomotion radial maze |
title_short |
Increase in Hippocampal Theta Oscillations during Spatial Decision Making |
title_full |
Increase in Hippocampal Theta Oscillations during Spatial Decision Making |
title_fullStr |
Increase in Hippocampal Theta Oscillations during Spatial Decision Making |
title_full_unstemmed |
Increase in Hippocampal Theta Oscillations during Spatial Decision Making |
title_sort |
Increase in Hippocampal Theta Oscillations during Spatial Decision Making |
author |
Belchior, Hindiael |
author_facet |
Belchior, Hindiael Lopes-dos-Santos, Vitor Tort, Adriano Bretanha Lopes Ribeiro, Sidarta Tollendal Gomes |
author_role |
author |
author2 |
Lopes-dos-Santos, Vitor Tort, Adriano Bretanha Lopes Ribeiro, Sidarta Tollendal Gomes |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Belchior, Hindiael Lopes-dos-Santos, Vitor Tort, Adriano Bretanha Lopes Ribeiro, Sidarta Tollendal Gomes |
dc.subject.por.fl_str_mv |
LFP oscillations spatial choice locomotion radial maze |
topic |
LFP oscillations spatial choice locomotion radial maze |
description |
The processing of spatial and mnemonic information is believed to depend on hippocampal theta oscillations (5–12 Hz). However, in rats both the power and the frequency of the theta rhythm are modulated by locomotor activity, which is a major confounding factor when estimating its cognitive correlates. Previous studies have suggested that hippocampal theta oscillations support decision-making processes. In this study, we investigated to what extent spatial decision making modulates hippocampal theta oscillations when controlling for variations in locomotion speed. We recorded local field potentials from the CA1 region of rats while animals had to choose one arm to enter for reward (goal) in a four-arm radial maze. We observed prominent theta oscillations during the decision-making period of the task, which occurred in the center of the maze before animals deliberately ran through an arm toward goal location. In speed-controlled analyses, theta power and frequency were higher during the decision period when compared to either an intertrial delay period (also at the maze center), or to the period of running toward goal location. In addition, theta activity was higher during decision periods preceding correct choices than during decision periods preceding incorrect choices. Altogether, our data support a cognitive function for the hippocampal theta rhythm in spatial decision making |
publishDate |
2014 |
dc.date.accessioned.fl_str_mv |
2014-03-13T16:16:48Z |
dc.date.available.fl_str_mv |
2014-03-13T16:16:48Z |
dc.date.issued.fl_str_mv |
2014-02 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BELCHIOR, Hindiael et. al. Increase in Hippocampal Theta Oscillations during Spatial Decision Making. Hippocampus, fev., 2014. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/jspui/handle/1/11785 |
dc.identifier.issn.none.fl_str_mv |
1050-9631 |
identifier_str_mv |
BELCHIOR, Hindiael et. al. Increase in Hippocampal Theta Oscillations during Spatial Decision Making. Hippocampus, fev., 2014. 1050-9631 |
url |
https://repositorio.ufrn.br/jspui/handle/1/11785 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFRN instname:Universidade Federal do Rio Grande do Norte (UFRN) instacron:UFRN |
instname_str |
Universidade Federal do Rio Grande do Norte (UFRN) |
instacron_str |
UFRN |
institution |
UFRN |
reponame_str |
Repositório Institucional da UFRN |
collection |
Repositório Institucional da UFRN |
bitstream.url.fl_str_mv |
https://repositorio.ufrn.br/bitstream/1/11785/1/Ribeiro_Increase_in_hippocampal_theta.pdf https://repositorio.ufrn.br/bitstream/1/11785/2/license.txt https://repositorio.ufrn.br/bitstream/1/11785/7/Ribeiro_Increase_in_hippocampal_theta.pdf.txt https://repositorio.ufrn.br/bitstream/1/11785/8/Ribeiro_Increase_in_hippocampal_theta.pdf.jpg |
bitstream.checksum.fl_str_mv |
87e5057d139c9d67d8905c5da27ae4ef 8a4605be74aa9ea9d79846c1fba20a33 6d0812b2668e698fb589116eecc06205 7c0bc82b67e8fc19b23c3b41841faef3 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN) |
repository.mail.fl_str_mv |
|
_version_ |
1802117496487018496 |