Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/handle/123456789/52464 |
Resumo: | Background and purpose: Liquid embolic agents are increasingly used to treat vascular malformations. We sought to assess embolization with these agents by using a dual-lumen balloon catheter in an experimental setting. Materials and methods: Eighteen injections of liquid embolic agents were performed in the rete mirabile of swine. We used 3 methods to control liquid embolic agent reflux: 1) dual-lumen balloon-catheter (group A, n = 8); 2) injection of liquid embolic agent after proximal n-BCA plug formation through a second microcatheter (group B, n = 4); and 3) standard liquid embolic agent injection (group C, controls, n = 6). The following outcomes were graded by using ordinal scales by angiography, macrophotography, and radiography of retia after euthanasia: 1) angiographic and pathologic extent of liquid embolic agent embolization of the rete, 2) reflux of liquid embolic agents in the parent artery, and 3) density of liquid embolic agents in the proximal rete. Technical complications were also recorded. A successful injection was defined as an embolization that reached the contralateral rete without reflux into proximal external branches. Exact logistic regression analyses were performed to compare groups. Results: There were significant differences among groups for reflux (P = .029) and liquid embolic agent density in the proximal rete (P = .014), while extension to the contralateral rete did not reach statistical significance (P = .07). Injections differed among groups (P = .004), with dual-lumen balloon-catheter injections more frequently successful compared with control injections (P = .019). Conclusions: Dual-lumen balloon catheters allowed better liquid embolic agent injections than standard injections. |
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Gentric, Jean-ChristopheRaymond, JeanBatista, André LimaSalazkin, IGevry, G.Darsaut, Tim E.2023-05-17T19:12:04Z2023-05-17T19:12:04Z2015-05BATISTA, André Lima, et al. Dual-Lumen Balloon Catheters May Improve Liquid Embolization of Vascular Malformations: an experimental study in swine. American Journal Of Neuroradiology, [S.L.], v. 36, n. 5, p. 977-981, 15 jan. 2015. American Society of Neuroradiology (ASNR). http://dx.doi.org/10.3174/ajnr.a4211https://repositorio.ufrn.br/handle/123456789/5246410.3174/ajnr.A4211American Society of NeuroradiologyLEA = liquid embolic agentPHIL = Precipitating Hydrophobic Injectable LiquidDual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBackground and purpose: Liquid embolic agents are increasingly used to treat vascular malformations. We sought to assess embolization with these agents by using a dual-lumen balloon catheter in an experimental setting. Materials and methods: Eighteen injections of liquid embolic agents were performed in the rete mirabile of swine. We used 3 methods to control liquid embolic agent reflux: 1) dual-lumen balloon-catheter (group A, n = 8); 2) injection of liquid embolic agent after proximal n-BCA plug formation through a second microcatheter (group B, n = 4); and 3) standard liquid embolic agent injection (group C, controls, n = 6). The following outcomes were graded by using ordinal scales by angiography, macrophotography, and radiography of retia after euthanasia: 1) angiographic and pathologic extent of liquid embolic agent embolization of the rete, 2) reflux of liquid embolic agents in the parent artery, and 3) density of liquid embolic agents in the proximal rete. Technical complications were also recorded. A successful injection was defined as an embolization that reached the contralateral rete without reflux into proximal external branches. Exact logistic regression analyses were performed to compare groups. Results: There were significant differences among groups for reflux (P = .029) and liquid embolic agent density in the proximal rete (P = .014), while extension to the contralateral rete did not reach statistical significance (P = .07). Injections differed among groups (P = .004), with dual-lumen balloon-catheter injections more frequently successful compared with control injections (P = .019). Conclusions: Dual-lumen balloon catheters allowed better liquid embolic agent injections than standard injections.porreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNinfo:eu-repo/semantics/openAccessORIGINALDualLumenBalloonCatheters_Batista_etal_2015.pdfDualLumenBalloonCatheters_Batista_etal_2015.pdfapplication/pdf1300004https://repositorio.ufrn.br/bitstream/123456789/52464/1/DualLumenBalloonCatheters_Batista_etal_2015.pdf902d63b89b5421265459a34e36669660MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/52464/2/license.txte9597aa2854d128fd968be5edc8a28d9MD52123456789/524642023-05-17 16:12:37.594oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2023-05-17T19:12:37Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine |
title |
Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine |
spellingShingle |
Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine Gentric, Jean-Christophe LEA = liquid embolic agent PHIL = Precipitating Hydrophobic Injectable Liquid |
title_short |
Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine |
title_full |
Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine |
title_fullStr |
Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine |
title_full_unstemmed |
Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine |
title_sort |
Dual-lumen balloon catheters may improve liquid embolization of vascular malformations: an experimental study in swine |
author |
Gentric, Jean-Christophe |
author_facet |
Gentric, Jean-Christophe Raymond, Jean Batista, André Lima Salazkin, I Gevry, G. Darsaut, Tim E. |
author_role |
author |
author2 |
Raymond, Jean Batista, André Lima Salazkin, I Gevry, G. Darsaut, Tim E. |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Gentric, Jean-Christophe Raymond, Jean Batista, André Lima Salazkin, I Gevry, G. Darsaut, Tim E. |
dc.subject.por.fl_str_mv |
LEA = liquid embolic agent PHIL = Precipitating Hydrophobic Injectable Liquid |
topic |
LEA = liquid embolic agent PHIL = Precipitating Hydrophobic Injectable Liquid |
description |
Background and purpose: Liquid embolic agents are increasingly used to treat vascular malformations. We sought to assess embolization with these agents by using a dual-lumen balloon catheter in an experimental setting. Materials and methods: Eighteen injections of liquid embolic agents were performed in the rete mirabile of swine. We used 3 methods to control liquid embolic agent reflux: 1) dual-lumen balloon-catheter (group A, n = 8); 2) injection of liquid embolic agent after proximal n-BCA plug formation through a second microcatheter (group B, n = 4); and 3) standard liquid embolic agent injection (group C, controls, n = 6). The following outcomes were graded by using ordinal scales by angiography, macrophotography, and radiography of retia after euthanasia: 1) angiographic and pathologic extent of liquid embolic agent embolization of the rete, 2) reflux of liquid embolic agents in the parent artery, and 3) density of liquid embolic agents in the proximal rete. Technical complications were also recorded. A successful injection was defined as an embolization that reached the contralateral rete without reflux into proximal external branches. Exact logistic regression analyses were performed to compare groups. Results: There were significant differences among groups for reflux (P = .029) and liquid embolic agent density in the proximal rete (P = .014), while extension to the contralateral rete did not reach statistical significance (P = .07). Injections differed among groups (P = .004), with dual-lumen balloon-catheter injections more frequently successful compared with control injections (P = .019). Conclusions: Dual-lumen balloon catheters allowed better liquid embolic agent injections than standard injections. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-05 |
dc.date.accessioned.fl_str_mv |
2023-05-17T19:12:04Z |
dc.date.available.fl_str_mv |
2023-05-17T19:12:04Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BATISTA, André Lima, et al. Dual-Lumen Balloon Catheters May Improve Liquid Embolization of Vascular Malformations: an experimental study in swine. American Journal Of Neuroradiology, [S.L.], v. 36, n. 5, p. 977-981, 15 jan. 2015. American Society of Neuroradiology (ASNR). http://dx.doi.org/10.3174/ajnr.a4211 |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/handle/123456789/52464 |
dc.identifier.doi.none.fl_str_mv |
10.3174/ajnr.A4211 |
identifier_str_mv |
BATISTA, André Lima, et al. Dual-Lumen Balloon Catheters May Improve Liquid Embolization of Vascular Malformations: an experimental study in swine. American Journal Of Neuroradiology, [S.L.], v. 36, n. 5, p. 977-981, 15 jan. 2015. American Society of Neuroradiology (ASNR). http://dx.doi.org/10.3174/ajnr.a4211 10.3174/ajnr.A4211 |
url |
https://repositorio.ufrn.br/handle/123456789/52464 |
dc.language.iso.fl_str_mv |
por |
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por |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
American Society of Neuroradiology |
publisher.none.fl_str_mv |
American Society of Neuroradiology |
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reponame:Repositório Institucional da UFRN instname:Universidade Federal do Rio Grande do Norte (UFRN) instacron:UFRN |
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Universidade Federal do Rio Grande do Norte (UFRN) |
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