Application of Partial Directed Coherence to the Analysis of Resting-State EEG-fMRI Data

• Autor(a) principal: Biazoli Jr., Claudinei E.
• Data de Publicação: 2013
• Outros Autores: Sturzbecher, Marcio, White, Thomas P., Onias, Heloisa Helena dos Santos, Andrade, Katia Cristine, Araújo, Dráulio Barros de, Sato, João R.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRN
• Texto Completo: https://repositorio.ufrn.br/jspui/handle/123456789/23293
• topic: default mode network; directed coherence; Granger causality; resting-state networks; simultaneous data acquisition

The simultaneous acquisition of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) data potentially allows measurement of brain signals with both high spatial and temporal resolution. Partial directed coherence (PDC) is a Granger causality measure in the frequency domain, which is often used to infer the intensity of information flow over the brain from EEG data. In the current study, we propose a new approach to investigate functional connectivity in resting-state (RS) EEG-fMRI data by combining time-varying PDC with the analysis of blood oxygenation level-dependent (BOLD) signal fluctuations. Basically, we aim to identify brain circuits that are more active when the information flow is increased between distinct remote neuronal modules. The usefulness of the proposed method is illustrated by application to simultaneously recorded EEG-fMRI data from healthy subjects at rest. Using this approach, we decomposed the nodes of RS networks in fMRI data according to the frequency band and directed flow of information provided from EEG. This approach therefore has the potential to inform our understanding of the regional characteristics of oscillatory processes in the human brain.