Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio

Detalhes bibliográficos
Autor(a) principal: Oliveira, Thiago Costa de
Data de Publicação: 2013
Tipo de documento: Trabalho de conclusão de curso
Idioma: por
Título da fonte: Repositório Institucional da UFS
Texto Completo: http://ri.ufs.br/jspui/handle/riufs/8389
Resumo: OBJECTIVE: To evaluate parathyroid function and mineral metabolism in psychiatric patients users of lithium salts. METHODS: We measured the serum levels of calcium, ionized calcium, inorganic phosphorus, alkaline phosphatase, albumin, parathyroid hormone (PTH), urea, creatinine, 25-hydroxy-vitamin D and lithium of 35 patients diagnosed with bipolar disorder in use of lithium carbonate (LC) for at least one year (Lithium Group – LG) and 35 healthy subjects (Control Group – CG). RESULTS: The LG and CG were matched by sex and age. There was only statistic difference in relation to the levels of PTH and ionized calcium, with p < 0,004 and p < 0,03, respectively. Normocalcemic hyperparathyroidism (HPT) was found in eight (22,8%) LG patients and in none of the CG. There was no correlation between litemia, usage time and dosage of LC. CONCLUSION: Our data demonstrate that lithium may create an imbalance in the parathyroid axis, characterized in normocalcemic HPT
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spelling Oliveira, Thiago Costa dePereira, Francisco de Assis2018-06-19T18:02:04Z2018-06-19T18:02:04Z2013-08-31OLIVEIRA, Thiago Costa de. Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio. Aracaju, SE, 2013. TCC (Graduação em Medicina) - Departamento de Medicina, Aracaju, 2013.http://ri.ufs.br/jspui/handle/riufs/8389OBJECTIVE: To evaluate parathyroid function and mineral metabolism in psychiatric patients users of lithium salts. METHODS: We measured the serum levels of calcium, ionized calcium, inorganic phosphorus, alkaline phosphatase, albumin, parathyroid hormone (PTH), urea, creatinine, 25-hydroxy-vitamin D and lithium of 35 patients diagnosed with bipolar disorder in use of lithium carbonate (LC) for at least one year (Lithium Group – LG) and 35 healthy subjects (Control Group – CG). RESULTS: The LG and CG were matched by sex and age. There was only statistic difference in relation to the levels of PTH and ionized calcium, with p < 0,004 and p < 0,03, respectively. Normocalcemic hyperparathyroidism (HPT) was found in eight (22,8%) LG patients and in none of the CG. There was no correlation between litemia, usage time and dosage of LC. CONCLUSION: Our data demonstrate that lithium may create an imbalance in the parathyroid axis, characterized in normocalcemic HPTOBJETIVO: Avaliar a função paratireoideana e o metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio. MÉTODOS: Foram avaliados os níveis séricos de cálcio total, cálcio iônico, fósforo inorgânico, fosfatase alcalina, albumina, paratormônio (PTH), ureia, creatinina, 25-hidroxi-vitamina D e lítio de 35 pacientes diagnosticados com transtorno afetivo bipolar usuários de carbonato de lítio (CL) há pelo menos um ano (Grupo Lítio – GL) e 35 indivíduos saudáveis (Grupo Controle – GC). RESULTADOS: O GL e o GC foram pareados por sexo e idade. Somente observou-se diferença estatística em relação aos níveis de PTH e cálcio iônico, com p < 0,004 e p < 0,03, respectivamente. Hiperparatireoidismo (HPT) normocalcêmico foi encontrado em oito (22,8%) pacientes do GL e em nenhum do GC. No GL, não houve correlação entre litemia, tempo de uso e posologia do CL. CONCLUSÃO: Nossos dados demonstram que o lítio pode suscitar um desequilíbrio no eixo paratireoideano, caracterizado pelo HPT normocalcêmico.Aracaju-(SE)porMedicinaSaúdeLítioMetabolismohiperparatireoidismoGlândulas paratireóidesMedicineLithiumMetabolismhyperparathyroidismParathyroid glandsCIENCIAS DA SAUDE::MEDICINAAvaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítioEvaluation of parathyroid function and mineral metabolism in psychiatric patients using lithium saltsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal de SergipeDME - Departamento de Medicina – Aracaju - Presencialreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/8389/1/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD51ORIGINALThiago_Costa_Oliveira.pdfThiago_Costa_Oliveira.pdfapplication/pdf345472https://ri.ufs.br/jspui/bitstream/riufs/8389/2/Thiago_Costa_Oliveira.pdf509312459a5e8c68e955f0cde9340ce7MD52TEXTThiago_Costa_Oliveira.pdf.txtThiago_Costa_Oliveira.pdf.txtExtracted texttext/plain116960https://ri.ufs.br/jspui/bitstream/riufs/8389/3/Thiago_Costa_Oliveira.pdf.txt2961809063a570924dcd254184460b73MD53THUMBNAILThiago_Costa_Oliveira.pdf.jpgThiago_Costa_Oliveira.pdf.jpgGenerated Thumbnailimage/jpeg1444https://ri.ufs.br/jspui/bitstream/riufs/8389/4/Thiago_Costa_Oliveira.pdf.jpg71d621f514aaba4ffdec7183c4b903e3MD54riufs/83892018-06-19 15:02:05.044oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2018-06-19T18:02:05Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio
dc.title.alternative.eng.fl_str_mv Evaluation of parathyroid function and mineral metabolism in psychiatric patients using lithium salts
title Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio
spellingShingle Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio
Oliveira, Thiago Costa de
Medicina
Saúde
Lítio
Metabolismo
hiperparatireoidismo
Glândulas paratireóides
Medicine
Lithium
Metabolism
hyperparathyroidism
Parathyroid glands
CIENCIAS DA SAUDE::MEDICINA
title_short Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio
title_full Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio
title_fullStr Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio
title_full_unstemmed Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio
title_sort Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio
author Oliveira, Thiago Costa de
author_facet Oliveira, Thiago Costa de
author_role author
dc.contributor.author.fl_str_mv Oliveira, Thiago Costa de
dc.contributor.advisor1.fl_str_mv Pereira, Francisco de Assis
contributor_str_mv Pereira, Francisco de Assis
dc.subject.por.fl_str_mv Medicina
Saúde
Lítio
Metabolismo
hiperparatireoidismo
Glândulas paratireóides
topic Medicina
Saúde
Lítio
Metabolismo
hiperparatireoidismo
Glândulas paratireóides
Medicine
Lithium
Metabolism
hyperparathyroidism
Parathyroid glands
CIENCIAS DA SAUDE::MEDICINA
dc.subject.eng.fl_str_mv Medicine
Lithium
Metabolism
hyperparathyroidism
Parathyroid glands
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::MEDICINA
description OBJECTIVE: To evaluate parathyroid function and mineral metabolism in psychiatric patients users of lithium salts. METHODS: We measured the serum levels of calcium, ionized calcium, inorganic phosphorus, alkaline phosphatase, albumin, parathyroid hormone (PTH), urea, creatinine, 25-hydroxy-vitamin D and lithium of 35 patients diagnosed with bipolar disorder in use of lithium carbonate (LC) for at least one year (Lithium Group – LG) and 35 healthy subjects (Control Group – CG). RESULTS: The LG and CG were matched by sex and age. There was only statistic difference in relation to the levels of PTH and ionized calcium, with p < 0,004 and p < 0,03, respectively. Normocalcemic hyperparathyroidism (HPT) was found in eight (22,8%) LG patients and in none of the CG. There was no correlation between litemia, usage time and dosage of LC. CONCLUSION: Our data demonstrate that lithium may create an imbalance in the parathyroid axis, characterized in normocalcemic HPT
publishDate 2013
dc.date.issued.fl_str_mv 2013-08-31
dc.date.accessioned.fl_str_mv 2018-06-19T18:02:04Z
dc.date.available.fl_str_mv 2018-06-19T18:02:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/bachelorThesis
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dc.identifier.citation.fl_str_mv OLIVEIRA, Thiago Costa de. Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio. Aracaju, SE, 2013. TCC (Graduação em Medicina) - Departamento de Medicina, Aracaju, 2013.
dc.identifier.uri.fl_str_mv http://ri.ufs.br/jspui/handle/riufs/8389
identifier_str_mv OLIVEIRA, Thiago Costa de. Avaliação da função paratireoideana e do metabolismo mineral em pacientes psiquiátricos usuários de sais de lítio. Aracaju, SE, 2013. TCC (Graduação em Medicina) - Departamento de Medicina, Aracaju, 2013.
url http://ri.ufs.br/jspui/handle/riufs/8389
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dc.publisher.initials.fl_str_mv Universidade Federal de Sergipe
dc.publisher.department.fl_str_mv DME - Departamento de Medicina – Aracaju - Presencial
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