Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | https://ri.ufs.br/handle/riufs/3843 |
Resumo: | Background: In view of the high mortality due to Cardiovascular Diseases in the world, a stratification of the main risk factors and correct choice of the diagnostic modality is necessary. Several studies have shown that the calcium score (CS) has a low risk of cardiovascular events. However, the frequency of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized medical literature. Objective: To evaluate the frequency of coronary atherosclerotic plaques and associated factors in patients with CS. Methods: This was a prospective, cross-sectional study with 367 volunteers with zero CS through the realization CS test and coronary computed tomography angiography (CCTA), from 2011 to 2016, in four imaging centers. The sample was obtained for convenience and consecutively. Results: The frequency of atherosclerotic plaque in the coronary arteries of the 367 patients with zero CS was 9.3% (34 individuals); in this subgroup the mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), some in more than one segment. The frequency of non-obese individuals (90.6% vs 9.4%, p = 0.037) and those of alcoholics (55.9% vs 44.1%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, Variable, odds ratio of 3.4 for the development of these plaques. Conclusions: The frequency of atherosclerotic plaque with zero CS was considerable, evidencing that the absence of calcification, through the CCTA, does not exclude plaque and nor obstructive lesion, mainly in the non-obese and the alcoholic. |
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Gabriel, Fabíola SantosOliveira, Joselina Luzia Menezeshttp://lattes.cnpq.br/55898827382094772017-09-26T12:17:58Z2017-09-26T12:17:58Z2017-06-02GABRIEL, Fabíola Santos. Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero. 2017. 76 f. Dissertação (Pós-Graduação em Ciências da Saúde) - Universidade Federal de Sergipe, Aracaju, 2017.https://ri.ufs.br/handle/riufs/3843Background: In view of the high mortality due to Cardiovascular Diseases in the world, a stratification of the main risk factors and correct choice of the diagnostic modality is necessary. Several studies have shown that the calcium score (CS) has a low risk of cardiovascular events. However, the frequency of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized medical literature. Objective: To evaluate the frequency of coronary atherosclerotic plaques and associated factors in patients with CS. Methods: This was a prospective, cross-sectional study with 367 volunteers with zero CS through the realization CS test and coronary computed tomography angiography (CCTA), from 2011 to 2016, in four imaging centers. The sample was obtained for convenience and consecutively. Results: The frequency of atherosclerotic plaque in the coronary arteries of the 367 patients with zero CS was 9.3% (34 individuals); in this subgroup the mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), some in more than one segment. The frequency of non-obese individuals (90.6% vs 9.4%, p = 0.037) and those of alcoholics (55.9% vs 44.1%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, Variable, odds ratio of 3.4 for the development of these plaques. Conclusions: The frequency of atherosclerotic plaque with zero CS was considerable, evidencing that the absence of calcification, through the CCTA, does not exclude plaque and nor obstructive lesion, mainly in the non-obese and the alcoholic.Fundamento: Diante da alta mortalidade por Doenças Cardiovasculares no mundo fazse necessário a estratificação dos principais fatores de riscos e escolha correta da modalidade diagnóstica. Diversos estudos demonstraram que escore de cálcio (EC) zero caracteriza baixo risco de eventos cardiovasculares. No entanto, a frequência de indivíduos portadores de placa aterosclerótica coronária com EC zero é conflitante na literatura médica especializada. Objetivo: Avaliar a frequência de placa aterosclerótica coronária e fatores associados em portadores de EC zero, assim como determinar o grau de obstrução das mesmas. Métodos: Trata-se de estudo transversal, prospectivo e com 367 voluntários portadores de EC zero mediante a realização de EC e angiotomografia computadorizada de coronárias (ATCC), no período de 2011 a 2016, em quatro centro de imagens. A amostra foi obtida por conveniência e de forma consecutiva. Resultados: A frequência de placa aterosclerótica nas artérias coronárias dos 367 pacientes com EC zero foi de 9,3% (34 indivíduos); neste subgrupo a média de idade foi de 52±10 anos, 18 (52,9%) eram mulheres e 16 (47%) exibiam obstruções coronarianas significativas (> 50%), alguns em mais de um segmento. A frequência de não obesos (90,6% vs 9,4%; p=0,037) e de etilistas (55,9% vs 44,1%; p=0,015) foi significativamente maior nos portadores de placa aterosclerótica, apresentando, cada variável, odds ratio de 3,4 para o desenvolvimento das referidas placas. Conclusões: A frequência de placa aterosclerótica com EC zero foi considerável, evidenciando que a ausência de calcificação, mediante a ATCC, não exclui placa e nem lesão obstrutiva principalmente nos não obesos e etilistas.application/pdfporUniversidade Federal de SergipePós-Graduação em Ciências da SaúdeUFSBrasilDoença das coronáriasPlaca ateroscleróticaTomografia computadorizada multidetectoresAtherosclerotic plaqueCoronary artery diseaseMultidetector computed tomographyCIENCIAS DA SAUDEPlaca aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zeroAtherosclerotic plaque to coronary angiotomography in patients with a zero calcium scoreinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSTEXTFABIOLA_SANTOS_GABRIEL.pdf.txtFABIOLA_SANTOS_GABRIEL.pdf.txtExtracted texttext/plain97835https://ri.ufs.br/jspui/bitstream/riufs/3843/2/FABIOLA_SANTOS_GABRIEL.pdf.txtfeac5fb3f7af692ba1c2e253531fce20MD52THUMBNAILFABIOLA_SANTOS_GABRIEL.pdf.jpgFABIOLA_SANTOS_GABRIEL.pdf.jpgGenerated Thumbnailimage/jpeg1280https://ri.ufs.br/jspui/bitstream/riufs/3843/3/FABIOLA_SANTOS_GABRIEL.pdf.jpgb923949d85e8c8194048591e1be006edMD53ORIGINALFABIOLA_SANTOS_GABRIEL.pdfapplication/pdf2088192https://ri.ufs.br/jspui/bitstream/riufs/3843/1/FABIOLA_SANTOS_GABRIEL.pdfc5ff574cd89a9ccae058ade0df154b4dMD51riufs/38432017-11-28 16:59:21.942oai:ufs.br:riufs/3843Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-11-28T19:59:21Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.por.fl_str_mv |
Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero |
dc.title.alternative.eng.fl_str_mv |
Atherosclerotic plaque to coronary angiotomography in patients with a zero calcium score |
title |
Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero |
spellingShingle |
Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero Gabriel, Fabíola Santos Doença das coronárias Placa aterosclerótica Tomografia computadorizada multidetectores Atherosclerotic plaque Coronary artery disease Multidetector computed tomography CIENCIAS DA SAUDE |
title_short |
Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero |
title_full |
Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero |
title_fullStr |
Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero |
title_full_unstemmed |
Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero |
title_sort |
Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero |
author |
Gabriel, Fabíola Santos |
author_facet |
Gabriel, Fabíola Santos |
author_role |
author |
dc.contributor.author.fl_str_mv |
Gabriel, Fabíola Santos |
dc.contributor.advisor1.fl_str_mv |
Oliveira, Joselina Luzia Menezes |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/5589882738209477 |
contributor_str_mv |
Oliveira, Joselina Luzia Menezes |
dc.subject.por.fl_str_mv |
Doença das coronárias Placa aterosclerótica Tomografia computadorizada multidetectores |
topic |
Doença das coronárias Placa aterosclerótica Tomografia computadorizada multidetectores Atherosclerotic plaque Coronary artery disease Multidetector computed tomography CIENCIAS DA SAUDE |
dc.subject.eng.fl_str_mv |
Atherosclerotic plaque Coronary artery disease Multidetector computed tomography |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE |
description |
Background: In view of the high mortality due to Cardiovascular Diseases in the world, a stratification of the main risk factors and correct choice of the diagnostic modality is necessary. Several studies have shown that the calcium score (CS) has a low risk of cardiovascular events. However, the frequency of individuals with coronary atherosclerotic plaques and zero CS is conflicting in the specialized medical literature. Objective: To evaluate the frequency of coronary atherosclerotic plaques and associated factors in patients with CS. Methods: This was a prospective, cross-sectional study with 367 volunteers with zero CS through the realization CS test and coronary computed tomography angiography (CCTA), from 2011 to 2016, in four imaging centers. The sample was obtained for convenience and consecutively. Results: The frequency of atherosclerotic plaque in the coronary arteries of the 367 patients with zero CS was 9.3% (34 individuals); in this subgroup the mean age was 52 ± 10 years, 18 (52.9%) were women and 16 (47%) had significant coronary obstructions (> 50%), some in more than one segment. The frequency of non-obese individuals (90.6% vs 9.4%, p = 0.037) and those of alcoholics (55.9% vs 44.1%, p = 0.015) was significantly higher in patients with atherosclerotic plaques, Variable, odds ratio of 3.4 for the development of these plaques. Conclusions: The frequency of atherosclerotic plaque with zero CS was considerable, evidencing that the absence of calcification, through the CCTA, does not exclude plaque and nor obstructive lesion, mainly in the non-obese and the alcoholic. |
publishDate |
2017 |
dc.date.accessioned.fl_str_mv |
2017-09-26T12:17:58Z |
dc.date.available.fl_str_mv |
2017-09-26T12:17:58Z |
dc.date.issued.fl_str_mv |
2017-06-02 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
GABRIEL, Fabíola Santos. Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero. 2017. 76 f. Dissertação (Pós-Graduação em Ciências da Saúde) - Universidade Federal de Sergipe, Aracaju, 2017. |
dc.identifier.uri.fl_str_mv |
https://ri.ufs.br/handle/riufs/3843 |
identifier_str_mv |
GABRIEL, Fabíola Santos. Placa aterosclerótica à angiotomografia de coronárias em pacientes com escore de cálcio zero. 2017. 76 f. Dissertação (Pós-Graduação em Ciências da Saúde) - Universidade Federal de Sergipe, Aracaju, 2017. |
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https://ri.ufs.br/handle/riufs/3843 |
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Universidade Federal de Sergipe |
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Pós-Graduação em Ciências da Saúde |
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UFS |
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Brasil |
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Universidade Federal de Sergipe |
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